498 research outputs found

    Nodal surface semimetals: Theory and material realization

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    We theoretically study the three-dimensional topological semimetals with nodal surfaces protected by crystalline symmetries. Different from the well-known nodal-point and nodal-line semimetals, in these materials, the conduction and valence bands cross on closed nodal surfaces in the Brillouin zone. We propose different classes of nodal surfaces, both in the absence and in the presence of spin-orbit coupling (SOC). In the absence of SOC, a class of nodal surfaces can be protected by spacetime inversion symmetry and sublattice symmetry and characterized by a Z2\mathbb{Z}_2 index, while another class of nodal surfaces are guaranteed by a combination of nonsymmorphic two-fold screw-rotational symmetry and time-reversal symmetry. We show that the inclusion of SOC will destroy the former class of nodal surfaces but may preserve the latter provided that the inversion symmetry is broken. We further generalize the result to magnetically ordered systems and show that protected nodal surfaces can also exist in magnetic materials without and with SOC, given that certain magnetic group symmetry requirements are satisfied. Several concrete nodal-surface material examples are predicted via the first-principles calculations. The possibility of multi-nodal-surface materials is discussed.Comment: 13 pages, 12 figure

    Interference between distinguishable photons

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    Two-photon interference (TPI) lies at the heart of photonic quantum technologies. TPI is generally regarded as quantum interference stemming from the indistinguishability of identical photons, hence a common intuition prevails that TPI would disappear if photons are distinguishable. Here we disprove this perspective and uncover the essence of TPI. We report the first demonstration of TPI between distinguishable photons with their frequency separation up to 10410^4 times larger than their linewidths. We perform time-resolved TPI between an independent laser and single photons with ultralong coherence time (>10 μ>10\ \mus). We observe a maximum TPI visibility of 72%±2%72\%\pm 2\% well above the 50%50\% classical limit indicating the quantum feature, and simultaneously a broad visibility background and a classical beat visibility of less than 50%50\% reflecting the classical feature. These visibilities are independent of the photon frequency separation and show no difference between distinguishable and indistinguishable photons. Based on a general wave superposition model, we derive the cross-correlation functions which fully reproduce and explain the experiments. Our results reveal that TPI as the fourth-order interference arises from the second-order interference of two photons within the mutual coherence time and TPI is not linked to the photon indistinguishability. This work provides new insights into the nature of TPI with great implications in both quantum optics and photonic quantum technologies.Comment: 7 pages, 5 figures. Comments are welcome. arXiv admin note: substantial text overlap with arXiv:2404.0515

    Expression of the microRNA-143/145 cluster is decreased in hepatitis B virus-associated hepatocellular carcinoma and may serve as a biomarker for tumorigenesis in patients with chronic hepatitis B

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    The aims of the present study were to identify the expression profile of microRNA (miR)‑143/145 in hepatitis B virus (HBV)‑associated hepatocellular carcinoma (HCC), explore its association with prognosis and investigate whether the serum miR‑143/145 expression levels may serve as a diagnostic indicator of HBV‑associated HCC. The microRNA (miRNA) chromatin immunoprecipitation dataset was obtained from The Cancer Genome Atlas (TCGA) and the Gene Expression Omnibus databases, and analyzed using the Wilcoxon signed‑rank test. It was observed that the expression of miR‑143 and miR‑145 was decreased 1.5‑fold in HBV‑associated HCC samples compared with non‑tumor tissue in the TCGA and the GSE22058 datasets (P\u3c0.01). Using the reverse transcription‑quantitative polymerase chain reaction, it was further confirmed that miR‑143/145 and their host gene MIR143HG were downregulated in HBV‑associated HCC tissues compared with corresponding distal non‑tumor tissues. The lower level of miR‑143 and miR‑145 expression was associated with tumor differentiation, and may thus be responsible for a poor prognosis of patients with HBV‑associated HCC. The receiver‑operating characteristic (ROC) curves were used to explore the potential value of miR‑143 and miR‑145 as biomarkers for predicting HBV‑associated HCC tumorigenesis. In serum, miR‑143/145 were identified to be significantly decreased in patients with HBV‑associated HCC compared with negative control patients, and their associated areas under the ROC curves were calculated at 0.813 and 0.852 (P\u3c0.05), with each having a sensitivity and a specificity close to 0.80. These results indicated that the decreased expression of the miR‑143/145 cluster and their host gene MIR143HG in HBV‑associated HCC tissue was associated with prognosis, and each of these miRNAs may serve as a valuable diagnostic biomarker for predicting HBV‑associated HCC tumorigenesis

    Quantum and Classical Two-photon Interference of Single Photons with Ultralong Coherence Time

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    Two-photon interference (TPI) is a fundamental phenomenon in quantum optics and plays a crucial role in quantum information science and technology. TPI is commonly considered as quantum interference with an upper bound of 100%100\% for both the TPI visibility and the beat visibility in contrast to its classical counterpart with a maximum visibility of 50%50\%. However, this is not always the case. Here we report a simultaneous observation of quantum and classical TPI of single photons with ultralong coherence time which is longer than the photon correlation time by five orders of magnitude. We observe a TPI visibility of 94.3%±0.2%94.3\%\pm 0.2\% but a beat visibility of 50%50\%. Besides an anti-bunching central dip due to single-photon statistics, we observe two bunching side peaks in cross-correlation curves for indistinguishable photons. Using either classical wave superposition theory or quantum field approach, we derive the same expressions for the cross-correlation functions which reproduce and explain the experiments well. We conclude that quantum TPI with a stream of single photons is equivalent to classical TPI, both of which are the fourth-order interference arising from the second-order interference occurring on the time scale of photon coherence time.Comment: 7 pages, 4 figures, Comments are welcom

    Recent Advances in Soft Biological Tissue Manipulating Technologies

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    Biological soft tissues manipulation, including conventional (mechanical) and nonconventional (laser, waterjet and ultrasonic) processes, is critically required in most surgical innervations. However, the soft tissues, with their nature of anisotropic and viscoelastic mechanical properties, and high biological and heat sensitivities, are difficult to manipulated. Moreover, the mechanical and thermal induced damage on the surface and surrounding tissue during the surgery can impair the proliferative phase of healing. Thus, understanding the manipulation mechanism and the resulted surface damage is of importance to the community. In recent years, more and more scholars carried out researches on soft biological tissue cutting in order to improve the cutting performance of surgical instruments and reduce the surgery induced tissue damage. However, there is a lack of compressive review that focused on the recent advances in soft biological tissue manipulating technologies. Hence, this review paper attempts to provide an informative literature survey of the state-of-the-art of soft tissue manipulation processes in surgery. This is achieved by exploring and recollecting the different soft tissue manipulation techniques currently used, including mechanical, laser, waterjet and ultrasonic cutting and advanced anastomosis and reconstruction processes, with highlighting their governing removal mechanisms as well as the surface and subsurface damages
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