5 research outputs found
HGCN
Pytorch implementation of our paper “Learning spatial interaction representation with Heterogeneous Graph Convolution Networks for urban land-use inference”. </p
Enhanced Photodynamic of Carriers and Suppressed Charge Recombination Enable Approaching 18% Efficiency in Nonfullerene Organic Solar Cells
Regulation of the exciton generation, diffusion, and
carrier transport,
as well as optimization of the non-radiative energy loss could further
overcome the power conversion efficiency limitation of organic solar
cells. However, the relationship between exciton properties and non-radiative
energy loss has seldom been investigated. Herein, taking D18-series
devices as the research model, the exciton diffusion length (LD) and hole transfer dynamics can be remarkably
improved by the variation of electron-withdrawing halogen and the
non-radiative energy loss simultaneously can be suppressed. By combining
the analysis results of hole transfer, exciton diffusion, charge separation,
and recombination, this work demonstrates that the photo-induced exciton
in the chlorinated polymer donor can diffuse to a longer distance
within the effective exciton lifetime, suppress the exciton recombination,
and enhance device performance. The results define the relationship
between the exciton behaviors and non-radiative energy loss and further
reveal the significance of controlling the bulk heterojunction with
superior photo-physical properties
Rapid and Accurate Quantification of Viable <i>Lactobacillus</i> Cells in Infant Formula by Flow Cytometry Combined with Propidium Monoazide and Signal-Enhanced Fluorescence In Situ Hybridization
Lactobacillus is an important member
of the probiotic
bacterial family for regulating human intestinal microflora and preserving
its normalcy, and it has been widely used in infant formula. An appropriate
and feasible method to quantify viable Lactobacilli cells is urgently required to evaluate the quality of probiotic-fortified
infant formula. This study presents a rapid and accurate method to
count viable Lactobacilli cells in infant formula
using flow cytometry (FCM). First, Lactobacillus cells
were specifically and rapidly stained by oligonucleotide probes based
on a signal-enhanced fluorescence in situ hybridization (SEFISH) technique.
A DNA-binding fluorescent probe, propidium monoazide (PMA), was then
used to accurately recognize viable Lactobacillus cells. The entire process of this newly developed PMA-SEFISH-FCM
method was accomplished within 2.5 h, which included pretreatment,
dual staining, and FCM analysis; thus, this method showed considerably
shorter time-to-results than other rapid methods. This method also
demonstrated a good linear correlation (R2 = 0.9994) with the traditional plate-based method with a bacterial
recovery rate of 91.24%. To the best of our knowledge, the present
study is the first report of FCM combined with PMA and FISH for the
specific detection of viable bacterial cells
Additional file 1 of Changes in the small noncoding RNA transcriptome in osteosarcoma cells
Additional file 1. Table S1
Nanofibrous Dressing with Nanocomposite Monoporous Microspheres for Chemodynamic Antibacterial Therapy and Wound Healing
The excessive use of antibiotics and consequent bacterial
resistance
have emerged as crucial public safety challenges for humanity. As
a promising antibacterial treatment, using reactive oxygen species
(ROS) can effectively address this problem and has the advantages
of being highly efficient and having low toxicity. Herein, electrospinning
and electrospraying were employed to fabricate magnesium oxide (MgO)-based
nanoparticle composited polycaprolactone (PCL) nanofibrous dressings
for the chemodynamic treatment of bacteria-infected wounds. By utilizing
electrospraying, erythrocyte-like monoporous PCL microspheres incorporating
silver (Ag)- and copper (Cu)-doped MgO nanoparticles were generated,
and the unique microsphere-filament structure enabled efficient anchoring
on nanofibers. The composite dressings produced high levels of ROS,
as confirmed by the 2,7-dichloriflurescin fluorescent probe. The sustained
generation of ROS resulted in efficient glutathione oxidation and
a remarkable bacterial killing rate of approximately 99% against Staphylococcus aureus (S. aureus). These
dressings were found to be effective at treating externally infected
wounds. The unique properties of these composite nanofibrous dressings
suggest great potential for their use in the medical treatment of
bacteria-infected injuries