Additional file 1 of CHRNB2 represses pancreatic cancer migration and invasion via inhibiting β-catenin pathway

Additional file 1: Figure S1. The expression conditions between tumor and paired normal pancreas among 13 genes in pancreatic cancer patients. A-M Compared to the paired normal pancreas, tumor tissue of most pancreatic cancer patients in GSE15471 has lower CHRNB2 expression. (**: P < 0.01; ***: P < 0.001)

Additional file 2 of CHRNB2 represses pancreatic cancer migration and invasion via inhibiting β-catenin pathway

Additional file 2: Figure S2. Flow cytometry showed that CHRNB2 arrested pancreatic cancer cells in the G1 phase. A Cell cycle flow chart of T3M4 with CHRNB2 overexpression. B Cell cycle histogram including G1, S, and G2 stages of T3M4 with CHRNB2 overexpression. (**: P < 0.01; ***: P < 0.001)

Comparison of Nle in different generations and years.

<p>Comparison of Nle in different generations and years.</p

Likelihood profile comparison of single marker analysis with phenotypic data from 2012 and normalized, respectively.

<p>The threshold value of LOD = 2.5 was showed with green line.</p

Statistics of the pepper BY map based on InDel and SSR markers.

<p>^a Physical distance spanned by the BY map.</p><p>Statistics of the pepper BY map based on InDel and SSR markers.</p

Frequency distribution of Nle for different populations in 2012 and 2014.

<p>A: Parental lines (Left: BA3, Right: YNXML), B: F₁ population, the mean of parental lines were shown with black arrows, C and D: F₂ populations in 2012 and 2014, respectively.</p

Polymorphism screening of primers from different sources.

<p>Polymorphism screening of primers from different sources.</p

An interspecific genetic map of pepper based on 224 InDel and SSR markers, and the comparison with its physical map.

<p>A total of 13 LGs (LG1 ~ LG13) were assigned to the corresponding chromosomes (P1 ~ P12) based on anchored markers. P7 was divided into LG7 and LG8 due to insufficient linkage. Green lines indicate the synteny between the genetic and physical maps. Five SDRs on LG1 (= P1), LG7 (= P7), LG9 (= P8) and LG11 (= P10) are filled with a red color.</p

List of 12 important candidate genes for the <i>Nle2.2</i> of pepper and homologs of Arabidopsis.

<p>List of 12 important candidate genes for the <i>Nle2.2</i> of pepper and homologs of Arabidopsis.</p

Comparison of mapped QTLs for Nle among studies.

<p>^a LG1, LG 7 and LG22 from the [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0119389#pone.0119389.ref046" target="_blank">46</a>] were assigned onto the P6, P5 and P2 of the Zunla-1 genome by BLAST tool, respectively.</p><p>^b LG8 from the [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0119389#pone.0119389.ref031" target="_blank">31</a>] were suggestively assigned onto P1 in spite of most of the marker were anchored on P0.</p><p>Comparison of mapped QTLs for Nle among studies.</p