30 research outputs found
Strongly interacting matter from holographic QCD model
We introduce the 5-dimension dynamical holographic QCD model, which is
constructed in the graviton-dilaton-scalar framework with the dilaton
background field and the scalar field responsible for the
gluodynamics and chiral dynamics, respectively. We review our results on the
hadron spectra including the glueball and light meson spectra, QCD phase
transitions and transport properties in the framework of the dynamical
holographic QCD model.Comment: 8 pages, 8 figures, proceedings for QCD@Work2016, June 27-30,2014,
Martina Franca, Italy. arXiv admin note: text overlap with arXiv:1409.843
The electromagnetic form factors in the holographic QCD
In this study, we employ a modified soft-wall holographic model with four
flavors to investigate the meson spectra, decay constants, electromagnetic form
factors, and charge radius of various mesons. We obtain the spectra for vector,
axial vector, and pseudoscalar mesons. Decay constants are calculated and
compared with experimental and lattice QCD data. The pion and kaon
electromagnetic form factors are compared with the experimental data, and a
good agreement is achieved for the kaon at low . For the charmed mesons,
the electromagnetic form factors of the and and electric form
factors of the and are well consistent with the lattice QCD
data. Moreover, the electric, magnetic, and quadrupole form factors are
predicted for the , , , , , and mesons.
Furthermore, the charge radius of the vector, axial vector, and pseudoscalars,
including the strange and charmed mesons, are computed
Spatial metabolomics in head and neck tumors: a review
The joint analysis of single-cell transcriptomics, proteomics, lipidomics, metabolomics and spatial metabolomics is continually transforming our understanding of the mechanisms of metabolic reprogramming in tumor cells. Since head and neck tumor is the sixth most common tumor in the world, the study of the metabolic mechanism of its occurrence, development and prognosis is still undeveloped. In the past decade, this field has witnessed tremendous technological revolutions and considerable development that enables major breakthroughs to be made in the study of human tumor metabolism. In this review, a comprehensive comparison of traditional metabolomics and spatial metabolomics has been concluded, and the recent progress and challenges of the application of spatial metabolomics combined multi-omics in the research of metabolic reprogramming in tumors are reviewed. Furthermore, we also highlight the advances of spatial metabolomics in the study of metabolic mechanisms of head and neck tumors, and provide an outlook of its application prospects
Macrophages: plastic participants in the diagnosis and treatment of head and neck squamous cell carcinoma
Head and neck squamous cell carcinoma (HNSCC) rank among the most prevalent types of head and neck cancer globally. Unfortunately, a significant number of patients receive their diagnoses at advanced stages, limiting the effectiveness of available treatments. The tumor microenvironment (TME) is a pivotal player in HNSCC development, with macrophages holding a central role. Macrophages demonstrate diverse functions within the TME, both inhibiting and facilitating cancer progression. M1 macrophages are characterized by their phagocytic and immune activities, while M2 macrophages tend to promote inflammation and immunosuppression. Striking a balance between these different polarization states is essential for maintaining overall health, yet in the context of tumors, M2 macrophages typically prevail. Recent efforts have been directed at controlling the polarization states of macrophages, paving the way for novel approaches to cancer treatment. Various drugs and immunotherapies, including innovative treatments based on macrophages like engineering macrophages and CAR-M cell therapy, have been developed. This article provides an overview of the roles played by macrophages in HNSCC, explores potential therapeutic targets and strategies, and presents fresh perspectives on the future of HNSCC treatment
Electrical 180o switching of N\'eel vector in spin-splitting antiferromagnet
Antiferromagnetic spintronics have attracted wide attention due to its great
potential in constructing ultra-dense and ultra-fast antiferromagnetic memory
that suits modern high-performance information technology. The electrical 180o
switching of N\'eel vector is a long-term goal for developing
electrical-controllable antiferromagnetic memory with opposite N\'eel vectors
as binary "0" and "1". However, the state-of-art antiferromagnetic switching
mechanisms have long been limited for 90o or 120o switching of N\'eel vector,
which unavoidably require multiple writing channels that contradicts
ultra-dense integration. Here, we propose a deterministic switching mechanism
based on spin-orbit torque with asymmetric energy barrier, and experimentally
achieve electrical 180o switching of spin-splitting antiferromagnet Mn5Si3.
Such a 180o switching is read out by the N\'eel vector-induced anomalous Hall
effect. Based on our writing and readout methods, we fabricate an
antiferromagnet device with electrical-controllable high and low resistance
states that accomplishes robust write and read cycles. Besides fundamental
advance, our work promotes practical spin-splitting antiferromagnetic devices
based on spin-splitting antiferromagnet.Comment: 19 pages, 4 figure
Superconductivity in trilayer nickelate La4Ni3O10 under pressure
Nickelates gained a great deal of attention due to their similar crystal and
electronic structures of cuprates over the past few decades. Recently,
superconductivity with transition temperature exceeding liquid-nitrogen
temperature is discovered in La3Ni2O7, which belong to the Ruddlesden-Popper
(RP) phases Lan+1NinO3n+1 with n = 2. In this work, we go further and find
pressure-induced superconductivity in another RP phase La4Ni3O10 (n = 3) single
crystals. Our angle-resolved photoemission spectroscopy (ARPES) experiment
suggest that the electronic structure of La4Ni3O10 is very similar to that of
La3Ni2O7. We find that the density-wave like anomaly in resistivity is
progressively suppressed with increasing pressure. A typical phase diagram is
obtained with the maximum Tc of 21 Kelvin. Our study sheds light on the
exploration of unconventional superconductivity in nickelates.Comment: 16 pages, 5 figure