Using Header Session Messages to Filter-out Junk E-mails

Due to the popularity of Internet, e-mail use is the major activity when surfing Internet. However, in recent years, spam has become a major problem that is bothering the use of the e-mail. Many anti-spam filtering techniques have been implemented so far, such as RIPPER rule learning algorithm, Naïve Bayesian classifier, Support Vector Machine, Centroid Based, Decision trees or Memory-base filter. Most existed anti-spamming techniques filter junk emails out according to e-mail subjects and body messages. Nevertheless, subjects and e-mail contents are not the only cues for spamming judgment. In this paper, we present a new idea of filtering junk e-mail by utilizing the header session messages. In message head session, besides sender\u27s mail address, receiver\u27s mail address and time etc, users are not interested in other information. This paper conducted two content analyses. The first content analysis adopted 10,024 Junk e-mails collected by Spam Archive (http://spamarchive.org) in a two-months period. The second content analysis adopted 3,482 emails contributed by three volunteers for a one week period. According to content analysis results, this result shows that at most 92.5% of junk e-mails would be filtered out using message-ID, mail user agent, sender and receiver addresses in the header session as cues. In addition, the idea this study proposed may induce zero over block errors rate. This characteristic of zero over block errors rate is an important advantage for the antispamming approach this study proposed. This proposed idea of using header session messages to filter-out junk e-mails may coexist with other anti-spamming approaches. Therefore, no conflict would be found between the proposed idea and existing anti-spamming approaches

A SMIL-Based Catalog Presentation System in Electronic Commerce

Web-based catalog presentations play the key-enabling role in E-commerce in recent years. Existing catalog systems often acquire proprietary platforms, cannot deal with TV-like media objects, or consume network bandwidth inefficiently. With the emergence of advanced technologies of Web and multimedia, such hurdles can be removed. The Synchronized Multimedia Integration Language (SMIL), proposed by W3C allows Web designers to design complicated and vivid multimedia presentations in a declarative manner. These presentations are then rendered on a general-purpose browser by a SMIL player. Since the SMIL specification is quite new to the Internet and E-commerce societies, the functionality and applications of players is limited. In this paper, we propose a novel architecture based on Java JMF technology for tackling with such constraints. The effectiveness of the proposed system is validated through an experiment on product catalog presentations

Engineering a BCR-ABL–Activated Caspase for the Selective Elimination of Leukemic Cells

Increased understanding of the precise molecular mechanisms involved in cell survival and cell death signaling pathways offers the promise of harnessing these molecules to eliminate cancer cells without damaging normal cells. Tyrosine kinase oncoproteins promote the genesis of leukemias through both increased cell proliferation and inhibition of apoptotic cell death. Although tyrosine kinase inhibitors, such as the BCR-ABL inhibitor imatinib, have demonstrated remarkable efficacy in the clinic, drug-resistant leukemias emerge in some patients because of either the acquisition of point mutations or amplification of the tyrosine kinase, resulting in a poor long-term prognosis. Here, we exploit the molecular mechanisms of caspase activation and tyrosine kinase/adaptor protein signaling to forge a unique approach for selectively killing leukemic cells through the forcible induction of apoptosis. We have engineered caspase variants that can directly be activated in response to BCR-ABL. Because we harness, rather than inhibit, the activity of leukemogenic kinases to kill transformed cells, this approach selectively eliminates leukemic cells regardless of drug-resistant mutations