Further understanding the nature of Ω(2012)\Omega(2012) within a chiral quark model

In our previous works, we have analyzed the two-body strong decays of the low-lying $\Omega$ baryon states within a chiral quark model. The results show that the $\Omega(2012)$ resonance favors the three-quark state with $J^P=3/2^-$ classified in the quark model. With this assignment, in the present work we further study the three-body strong decay $\Omega(2012)\to \Xi^*(1530)\bar{K} \to \Xi\pi\bar{K}$ and coupled-channel effects on $\Omega(2012)$ from nearby channels $\Xi \bar{K}$, $\Omega\eta$ and $\Xi^*(1530)\bar{K}$ within the chiral quark model as well. It is found that the $\Omega(2012)$ resonance has a sizeable decay rate into the three-body final state $\Xi\pi\bar{K}$. The predicted ratio $R_{\Xi\bar{K}}^{\Xi\pi\bar{K}}=\mathcal{B}[\Omega(2012)\to \Xi^*(1530)\bar{K}\to \Xi\pi\bar{K}]/\mathcal{B}[\Omega(2012)\to \Xi\bar{K}]\simeq 12\%$ is close to the up limit $11\%$ measured by the Belle Collaboration in 2019, however, our predicted ratio is too small to be comparable with the recent data $0.97\pm 0.31$. Furthermore, our results show that the coupled-channel effects on the $\Omega(2012)$ is not large, its components should be dominated by the bare three-quark state, while the proportion of the molecular components is only $\sim 16\%$. To clarify the nature of $\Omega(2012)$, the ratio $R_{\Xi\bar{K}}^{\Xi\pi\bar{K}}$ is expected to be tested by other experiments.Comment: 7 pages, 3 figure

5-Methyl 3-(2-methyl­prop-3-yl) 2,6-di­methyl-4-(2-nitro­sophen­yl)pyridine-3,5-dicarboxyl­ate

In the title compound, C20H22N2O5, a photo-degradation product of the hypertension drug nisoldipine, the dihedral angle between the nitro­sophenyl ring and the pyridine ring is 75.7 (3)°. In the crystal structure, weak C—H⋯O hydrogen bonds help to establish the packing

N,N′-Bis(2-quinolylcarbon­yl)hydrazine

The title compound, C20H14N4O2, crystallizes in the ortho­rhom­bic system with a crystallographic twofold axis through the N—N bond. The mol­ecule is non-planar and the dihedral angle between two amide groups is 74.9 (2)°. An intra­molecular N—H⋯N hydrogen bond is present. In the crystal, the mol­ecules are packed in chains running along the c axis through inter­molecular N—H⋯O hydrogen bonds. These chains are further stabilized by inter­molecular C—H⋯O hydrogen bonds and C—H⋯π inter­actions leading to the formation of a three-dimensional network

THE PREDICTION OF FATIGUE-RELATED MUSCLE ADAPTATION IN DIFFERENT WORKLOAD DURING CYCLING ROWING EXERCISE

The purpose of this study was to identify the fatigue-related muscles during the different percentage of the maximal workload. Seven subjects were recruited and, firstly, performed the maximal workload test for 3 minutes. After 24 hours, the different workload tests (60%, 70% and 80% of the maximal workload) were used to reveal the fatigue-related muscle. The result showed that the biceps and triceps had the extreme contribution at the minor and greater workload. However, the neuromuscular fatigue threshold (NFT) is to predict the possibly fatigue muscle condition during the entire exercise. And the most contribution of the EMG expression didn’t stand for the greater value of the EMG number

In vitro anti-tumor activity in SGC-7901 human gastric cancer cells treated with dandelion extract

Purpose: To investigate the mechanisms of cytotoxicity of a dandelion extract against human gastric cancer cell line SGC-7901 cells.Methods: The 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide (MTT) assay, flow cytometry, and transwell assays were used to investigate the effects of a dandelion extract on cell proliferation, levels of apoptosis, and cell migration, respectively. Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) assessed the effects of a dandelion extract on the expression levels of genes regulating proliferation and apoptosis.Results: Dandelion extract exerted strong cytotoxic effects on the cancer cells. After exposure, apoptotic cells increased and cell migration was reduced. RT-qPCR assay revealed that dandelion extract significantly increased anti-proliferative and pro-apoptotic gene expression, including phosphate and tensin homology deleted on chromosome ten (Pten) and Bcl-2 Associated X protein (Bax) mRNA in the gastric cancer cells. The results also indicate that there was decreased pro-proliferative and antiapoptotic gene expression (i.e., extracellular signal-regulated kinase (Erk), Survivin, and B-cell lymphoma 2 (Bcl2) mRNA).Conclusion: The results suggest that dandelion extract is a potent gastric cancer cell proliferation, survival, and migration inhibitor with potential pharmaceutical applications for the prevention of gastric cancer.Keywords: dandelion extract, gastric cancer, cytotoxic effect, migration inhibitio

Complete Genome and Transcriptomes of Streptococcus parasanguinis FW213: Phylogenic Relations and Potential Virulence Mechanisms

Streptococcus parasanguinis, a primary colonizer of the tooth surface, is also an opportunistic pathogen for subacute endocarditis. The complete genome of strain FW213 was determined using the traditional shotgun sequencing approach and further refined by the transcriptomes of cells in early exponential and early stationary growth phases in this study. The transcriptomes also discovered 10 transcripts encoding known hypothetical proteins, one pseudogene, five transcripts matched to the Rfam and additional 87 putative small RNAs within the intergenic regions defined by the GLIMMER analysis. The genome contains five acquired genomic islands (GIs) encoding proteins which potentially contribute to the overall pathogenic capacity and fitness of this microbe. The differential expression of the GIs and various open reading frames outside the GIs at the two growth phases suggested that FW213 possess a range of mechanisms to avoid host immune clearance, to colonize host tissues, to survive within oral biofilms and to overcome various environmental insults. Furthermore, the comparative genome analysis of five S. parasanguinis strains indicates that albeit S. parasanguinis strains are highly conserved, variations in the genome content exist. These variations may reflect differences in pathogenic potential between the strains