3,203 research outputs found

    Gender equality and economic development : the role for information and communication technologies

    Get PDF
    The author focuses on the role that information and communication technologies (ICTs) can play in improving gender equality, so as to enhance long-term economic growth. Employing OLS and IV panel regressions with country fixed-effects, he shows that increases in the level of ICT infrastructure tend to improve gender equality in education and employment. In addition, the author shows that education among the general population is important for improving gender equality. The results provide evidence indicating that gender equality in education is an important contributor to gender equality in employment. Lastly, the results show that economic development tends to lead to some improvements in gender equality in the labor market. Hence, the use of ICTs to improve gender equality in education and employment may initiate a continuous cycle of positive reinforcing feedback effects between gender equality in employment and economic development, leading to further improvements in both.Housing&Human Habitats,Gender and Development,Agricultural Knowledge&Information Systems,Public Health Promotion,Health Monitoring&Evaluation,Housing&Human Habitats,Gender and Education,Health Monitoring&Evaluation,Agricultural Knowledge&Information Systems,Legal Products

    Linking representative household models with household surveys for poverty analysis : a comparison of alternative methodologies

    Get PDF
    The authors compare three approaches to linking representative-household macro models with micro household income data in terms of their implications for measuring the poverty and distributional effects of policy shocks. These approaches are a simple micro-accounting method, an extension of that method to account for changes in employment structure, and the Beta distribution approach. Even though in the authors simulation exercises the three methods do not lead to fundamentally different results in absolute terms, they show that potential differences in the measurement of distributional and poverty effects of policy shocks can be very large.Economic Theory&Research,Labor Policies,Health Economics&Finance,Services&Transfers to Poor,Environmental Economics&Policies,Inequality,Poverty Assessment,Health Economics&Finance,Environmental Economics&Policies,Economic Theory&Research

    Involvement of lipid rafts in adhesion-induced activation of Met and EGFR

    Get PDF
    <p>Abstract</p> <p>Background</p> <p>Cell adhesion has been shown to induce activation of certain growth factor receptors in a ligand-independent manner. However, the mechanism for such activation remains obscure.</p> <p>Methods</p> <p>Human epidermal carcinoma A431 cells were used as a model to examine the mechanism for adhesion-induced activation of hepatocyte growth factor receptor Met and epidermal growth factor receptor (EGFR). The cells were suspended and replated on culture dishes under various conditions. The phosphorylation of Met at Y1234/1235 and EGFR at Y1173 were used as indicators for their activation. The distribution of the receptors and lipid rafts on the plasma membrane were visualized by confocal fluorescent microscopy and total internal reflection microscopy.</p> <p>Results</p> <p>We demonstrate that Met and EGFR are constitutively activated in A431 cells, which confers proliferative and invasive potentials to the cells. The ligand-independent activation of Met and EGFR in A431 cells relies on cell adhesion to a substratum, but is independent of cell spreading, extracellular matrix proteins, and substratum stiffness. This adhesion-induced activation of Met and EGFR cannot be attributed to Src activation, production of reactive oxygen species, and the integrity of the cytoskeleton. In addition, we demonstrate that Met and EGFR are independently activated upon cell adhesion. However, partial depletion of Met and EGFR prevents their activation upon cell adhesion, suggesting that overexpression of the receptors is a prerequisite for their self-activation upon cell adhesion. Although Met and EGFR are largely distributed in 0.04% Triton-insoluble fractions (<it>i.e</it>. raft fraction), their activated forms are detected mainly in 0.04% Triton-soluble fractions (<it>i.e</it>. non-raft fraction). Upon cell adhesion, lipid rafts are accumulated at the cell surface close to the cell-substratum interface, while Met and EGFR are mostly excluded from the membrane enriched by lipid rafts.</p> <p>Conclusions</p> <p>Our results suggest for the first time that cell adhesion to a substratum may induce a polarized distribution of lipid rafts to the cell-substratum interface, which may allow Met and EGFR to be released from lipid rafts, thus leading to their activation in a ligand-independent manner.</p

    The new modelling method in urban development : case study in Rotterdam

    Get PDF
    Land-use transition, energy consumption, and temperature fluctuation are the three dominant topics we have investigated in this research. In the last century, 38 heat waves occurred in Europe, of which eleven were after 1900 and six after 2000 (IPCC, 2007). Local-climate changes due to urbanization are epitomized by the urban heat island (UHI), which mainly focuses on the interaction of land use and temperature. However, energy is also an important issue when we investigate the sustainable urban development. This research detects correlations between land-use transition, energy consumption, and temperature fluctuation in the Rotterdam area from 1996 till now. We use a series of maps to illustrate the relationship of temperature fluctuation and energy consumption. These two variables are linked via land-use maps. From the data set, the spatial parameters are estimated that have a significant effect on the correlation between temperature fluctuation and energy consumption. Finally we draw conclusions on the Rotterdam 2050 city scenario, taking the found spatial parameters into consideration

    Performance Analysis of Dual Unipolar/Bipolar Spectral Code in Optical CDMA Systems

    Get PDF
    This study analyzes and calculates dual unipolar and bipolar coded configurations of spectral-amplitude-coding opticalcode division multiple access (SAC-OCDMA) systems by using simulation methods. The important feature of theSAC-OCDMA systems is that multiple access interference (MAI) can be eliminated by code sequences of a fixed inphasecross-correlation value. This property can be effectively canceled multiple access interference by using balancedetection schemes. This study uses Walsh-Hadamard codes as signature codes for the unipolar and bipolar schemes.The coder and decoder structures are based on optical filters of fiber Bragg gratings (FBGs). The simulation results ofunipolar/bipolar coding structures are first presented by commercial simulation obtained using OptiSystem software.The simulation results show that the bit error rate (BER) through use of the bipolar coding method is superior to theunipolar scheme, especially when the received effect power is large. When the system needs good performance totransmit multimedia data, we can use bipolar scheme in the network. If the users only transmit voice data, the unipolarmethod can be employed. The eye diagram also shows that the bipolar encoding structure exhibits a wider openingthan the unipolar encoding structure. The flexible implementation of codewords assigns and integratable hardwaredesigns for the scheme with FBGs to realize dual coding OCDMA system is proposed

    Inter-language differences in the McGurk effects for Dutch and Cantonese listeners

    Get PDF
    • …
    corecore