Evaluation sur 24 mois de la pulpotomie à l’oxyde de zinc-eugénol sur des canines temporaires saines ou cariées

Pulpotomy is the most performed and controversial therapeutic in pediatric dentistry. Since formocresol is known to have a toxic effect on living tissues, plus a mutagenic and carcinogenic potential with a systemic uptake of formocresol via pulpotomized teeth, other alternative products have been investigated. Twenty-five decayed primary canines and twenty-five healthy primary canines necessitating disking for orthodontic purposes were pulpotomized using non modified Zinc Oxide Eugenol. The effects of this material were evaluated both clinically and radiographically. Post operative control examinations were performed at 1, 6, 12 and 24 months trying to detect spontaneous or stimulated pain, pathological tooth mobility, abscesses or fistulas, internal or external pathological tooth resorption, periapical bone destruction, or canal obliteration. Pain was absent at 24 months post operatively. Half of the treated canines presented with a mobility, while internal and external resorptions were more frequent in decayed teeth and their number increased with time. On the other hand, abscesses and fistulas were equally found in both treated groups. The observations were compared to others related to formocresol ferric sulfate, MTA, and laser pulpotomies, using the binominal law, or the comparative test of an observed proportion to a reference proportion. In this study, and based on the excessive negative results in both groups, we demonstrated that non fixative pulpotomies on temporary canines were a promising techniqueLa pulpotomie, est la thérapeutique pulpaire la plus couramment réalisée et la plus controversée en médecine dentaire pédiatrique. Les craintes concernant la diffusion systématique et la potentielle toxicité, allergénicité, carcinogénicité, en mutagénicité du formaldéhyde ont conduit à rechercher des alternatives à ce produit. Afin d’évaluer, selon des critères cliniques et radiologiques, l’action de l’oxyde de zinc-eugénol non modifié, l’une des alternatives au formocrésol, 25 canines temporaires cariées et 25 canines temporaires nécesitant un meulage dimensionnel dans le cadre de traitements interceptifs de dysharmonies dento-maxillaires (DDM) mineures du secteur antérieur, ont subi une pulpotomie à l’aide de ce matériau. Les contrôles post-opératoires ont été réalisés à 1, 6, 12 et 24 mois, à la recherche de douleur spontanée ou provoquée, de mobilité dentaire pathologique, d’abcès ou de fistule, de résorption radiculaire interne ou externe pathologique, de destruction osseuse péripicale ou d’oblitération canalaire. La douleur était inexistante à 24 mois. La moitié des canines traitées présentaient une mobilité alors que les résorptions internes et externes ont été rencontrées plus fréquemment dans le groupe « Carie » où le nombre augmentait avec le temps. Par ailleurs, le nombre d’abcès sans fistule s’observait de la même façon dans les deux groupes. Ces observations ont été comparées à celles relatives à la pulpotomie au formocrésol, au sulfate ferrique, au MTA et au laser, en utilisant le test de la loi binomiale ou le test de la comparaison d’une proportion observées à une proportion de référence. L’abondance de résultats négatifs dans les deux groupes démontre fortement que la pulpotomie non fixatrices sur des canines temporaires n’est pas une technique prometteuse

Papillon-Lefèvre Syndrome: Diagnosis, Dental Management, and a Case Report

Aim. This paper revisits Papillon-Lefèvre syndrome (PLS), addresses its diagnostic update and dental management, and reports a case of a 5-year-old Lebanese patient with consanguineously married parents. Background. PLS, also known as “keratoris palmoplantaris with periodontopathia” and “hyperkeratosis palmoplantaris with periodontosis,” is an extremely rare autosomal-recessive trait that combines a diffuse palmoplantar hyperkeratosis and a severe generalized, progressive prepubertal form of a precocious form of juvenile, aggressive periodontitis. Case Description. We are reporting a 5-year-old boy that sustained a spontaneous loss of all his primary teeth. At consultation, he was under treatment for hyperkeratosis of his palms and soles. Detailed family history of the child revealed that the patient’s parents, grandparents, and relatives were consanguineously married and two of his cousins displayed similar clinical signs (palmoplantar hyperkeratosis and premature loss of deciduous and most of the permanent teeth). Conclusion. PLS is an extremely rare disorder that usually becomes apparent from approximately 1-5 years of age. Genetic counseling should always be suggested to parents of affected children, informing them of chances of their offspring having the inherited disease

The Contribution of Various In Vitro Methodologies to Comprehending the Filling Ability of Root Canal Pastes in Primary Teeth

A void-free obturation during root canal treatment on primary teeth is currently very difficult to attain. In this study, the pulpectomy filling abilities of Bio-C Pulpecto (Angelus, Basil, Londrina, Paraná, Brazil) and of zinc oxide eugenol, or "ZOE" (DenPro, Prevest, New York, NY, USA), were compared using several in vitro techniques. Therefore, 30 primary anterior teeth were used in the present in vitro study. Analysis of variance (ANOVA), including a multiple comparison procedure (Holm-Sidak method, Dunn's Method, or Tukey test), was used. On micro-CT, Bio-C Pulpecto exhibited higher void percentages than did ZOE (10.3 ± 3.8%, and 3.5 ± 1.3%), respectively (p < 0.05). With digital microscopy, higher total void percentages were found in the BC (13.2 ± 26.7%) group compared to the ZOE (2.7 ± 2.8%) group (p < 0.05). With the CLSM, mean tubular penetration depths were higher for Bio-C Pulpecto than for ZOE in all canal thirds (p < 0.05). SEM images demonstrated no tags into dentinal tubules in either group throughout the three thirds. Moreover, higher statistically significant flowability was found for Bio-C (2.657 ± 0.06 mm) compared to ZOE (1.8 ± 0.13 mm) (p < 0.05). The findings of this study indicate that neither ZOE nor Bio-C Pulpecto appears to meet the criteria for an ideal root canal filling paste for primary teeth. This study laid the groundwork for future research by determining how micro-CT, digital microscopy, SEM, and CLSM contribute to our understanding of the filling process of primary teeth. More thorough research on the mechanism of root canal obturation on primary teeth is required to achieve a long-term successful root canal therapy in young children

Peptides in Dentistry: A Scoping Review

Currently, it remains unclear which specific peptides could be appropriate for applications in different fields of dentistry. The aim of this scoping review was to scan the contemporary scientific papers related to the types, uses and applications of peptides in dentistry at the moment. Literature database searches were performed in the following databases: PubMed/MEDLINE, Scopus, Web of Science, Embase, and Scielo. A total of 133 articles involving the use of peptides in dentistry-related applications were included. The studies involved experimental designs in animals, microorganisms, or cells; clinical trials were also identified within this review. Most of the applications of peptides included caries management, implant osseointegration, guided tissue regeneration, vital pulp therapy, antimicrobial activity, enamel remineralization, periodontal therapy, the surface modification of tooth implants, and the modification of other restorative materials such as dental adhesives and denture base resins. The in vitro and in vivo studies included in this review suggested that peptides may have beneficial effects for treating early carious lesions, promoting cell adhesion, enhancing the adhesion strength of dental implants, and in tissue engineering as healthy promotors of the periodontium and antimicrobial agents. The lack of clinical trials should be highlighted, leaving a wide space available for the investigation of peptides in dentistry