An atypical adenomatoid odontogenic tumour in the mandible: a report of a paediatric case

An adenomatoid odontogenic tumour (AOT) is a rare odontogenic tumour that is often misdiagnosed as an odontogenic cyst. To acquire additional information about AOT, all reports regarding AOT that had been cited in ‘Pub Med’ since 1990 onwards were reviewed. AOT accounts for about 1–9% of all odontogenic tumours. It is predominantly found in young and female patients, is located more often in the maxilla, and in most cases is associated with an unerupted permanent tooth. The differential diagnosis between AOT and other odontogenic tumours such as ameloblastoma should be well made to avoid extensive ablative surgery. However, AOT frequently resembles other odontogenic lesions such as dentigerous cysts or ameloblastoma. Immunohistochemically, AOT is characterized by positive reactions with certain cytokeratins. For illustration a rare case of an AOT in the mandible is presented that had atypical findings such as buccolingual cortical perforation and resorption with displacement of adjoining teeth.Keywords: adenomatoid odontogenic tumor, dentigerous cyst, odontogenic tumor, paediatric cas

Calcific myofibrosis due to pentazocine abuse: a case report

<p>Abstract</p> <p>Introduction</p> <p>Pentazocine, a synthetic narcotic analgesic, is commonly used for the relief of moderate to severe pain secondary to various conditions. It is usually well tolerated; however, adverse effects are not uncommon, especially when higher doses are used and when it is used in a dependent fashion. There have been reports of various complications associated with its use, including skin fibrosis, skin ulceration, abnormal skin pigmentation and symmetrical myopathy with fibrous myopathy. Fibrosis has usually been reported in the muscles at the site of injection of the drug. Being opioid in nature, it has a high abuse potential.</p> <p>Case presentation</p> <p>Here we report a case of pentazocine-induced calcific myofibrosis in a 42-year-old man involving muscles which were not injected with pentazocine.</p> <p>Conclusion</p> <p>This case highlights the care that needs to be taken when prescribing opioid analgesics, such as pentazocine, as routine painkillers. Patients who have history of substance abuse are more likely to abuse other agents, including prescription drugs. Rare consequences such as calcific myofibrosis are devastating and can cause significant lifelong disability.</p