30 research outputs found

    Expressive writing as a therapeutic intervention for people with advanced disease: A systematic review

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    © The Author(s) 2019. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.Background Expressive writing involves writing about stressful or traumatic experiences. Despite trials in people with advanced disease, no systematic review to date has critiqued the evidence on expressive writing in this population. To synthesise the evidence of the effects of expressive writing on pain, sleep, depression and anxiety in people with advanced disease. Methods A systematic review according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. CINAHL, CENTRAL, PsycINFO and PubMed were searched from January 1986 to March 2018. Other sources included clinical data registers and conference proceedings. Studies were included if they were randomised controlled trials that assessed the impact of an intervention involving expressive writing for adults with advanced disease and/or studies involving linguistic analysis on the expressive writing output. Methodological quality was assessed using the Cochrane risk of bias tool and the Mixed Methods Appraisal Tool. The Grading of Recommendations Assessment, Development and Evaluation tool was used to assess the level of evidence for the outcomes of interest. The protocol of this systematic review has been registered on PROSPERO (CRD42017058193). Results Six eligible studies with a total of 288 participants were identified, including four randomised controlled trials. All of the trials were in cancer and recruited predominantly women. None of the interventions were tailored to the population. Studies had methodological shortcomings and evidence was generally of low quality. Combined analysis of the four trials, involving 214 participants in total, showed no clear difference in the effect of expressive writing on sleep, anxiety or depression compared to an active control. Pain was not evaluated in the trials. In contrast, analysis of the four studies that included linguistic analysis alluded to linguistic mechanisms for potential effects. Conclusion Although the trial results suggest there is no benefit in expressive writing for people with advanced disease, the current evidence is limited. There is a need for more rigorous trials. It would be of benefit first to undertake exploratory research in trial design including how best to measure impact and in tailoring of the intervention to address the specific needs of people with advanced disease.Peer reviewedFinal Published versio

    A systematic review on the effectiveness of physical and rehabilitation interventions for chronic non-specific low back pain

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    Low back pain (LBP) is a common and disabling disorder in western society. The management of LBP comprises a range of different intervention strategies including surgery, drug therapy, and non-medical interventions. The objective of the present study is to determine the effectiveness of physical and rehabilitation interventions (i.e. exercise therapy, back school, transcutaneous electrical nerve stimulation (TENS), low level laser therapy, education, massage, behavioural treatment, traction, multidisciplinary treatment, lumbar supports, and heat/cold therapy) for chronic LBP. The primary search was conducted in MEDLINE, EMBASE, CINAHL, CENTRAL, and PEDro up to 22 December 2008. Existing Cochrane reviews for the individual interventions were screened for studies fulfilling the inclusion criteria. The search strategy outlined by the Cochrane Back Review Groups (CBRG) was followed. The following were included for selection criteria: (1) randomized controlled trials, (2) adult (≥18 years) population with chronic (≥12 weeks) non-specific LBP, and (3) evaluation of at least one of the main clinically relevant outcome measures (pain, functional status, perceived recovery, or return to work). Two reviewers independently selected studies and extracted data on study characteristics, risk of bias, and outcomes at short, intermediate, and long-term follow-up. The GRADE approach was used to determine the quality of evidence. In total 83 randomized controlled trials met the inclusion criteria: exercise therapy (n = 37), back school (n = 5), TENS (n = 6), low level laser therapy (n = 3), behavioural treatment (n = 21), patient education (n = 1), traction (n = 1), and multidisciplinary treatment (n = 6). Compared to usual care, exercise therapy improved post-treatment pain intensity and disability, and long-term function. Behavioural treatment was found to be effective in reducing pain intensity at short-term follow-up compared to no treatment/waiting list controls. Finally, multidisciplinary treatment was found to reduce pain intensity and disability at short-term follow-up compared to no treatment/waiting list controls. Overall, the level of evidence was low. Evidence from randomized controlled trials demonstrates that there is low quality evidence for the effectiveness of exercise therapy compared to usual care, there is low evidence for the effectiveness of behavioural therapy compared to no treatment and there is moderate evidence for the effectiveness of a multidisciplinary treatment compared to no treatment and other active treatments at reducing pain at short-term in the treatment of chronic low back pain. Based on the heterogeneity of the populations, interventions, and comparison groups, we conclude that there are insufficient data to draw firm conclusion on the clinical effect of back schools, low-level laser therapy, patient education, massage, traction, superficial heat/cold, and lumbar supports for chronic LBP

    Modified carbon-containing electrodes in stripping voltammetry of metals

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    Low temperature chemical preparation of semiconducting transition metal chalcogenide films for energy conversion and storage, lubrication and surface protection

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    A simple technique is presented for the production of films of transition metal disulfides such as MoS2, WS2, FeS2, or RuS2 by the reaction of transition metal carbonyls e.g. Mo CO 6, W CO 6, Fe CO 5, Ru3 CO 12 with a sulfur source e.g. S, H2S in an organic solvent e.g. benzene, toluene, xylene, mesitylene 1,3,5 trimethyl benzene at temperatures ranging between 80 to 165 C. The quality of the materials and films has been investigated and some applications are discussed. They include use of the chemically prepared sulfides as photoactive materials e.g. MoS2, WS2, FeS2 , as lubricating films MoS2 , as electrodes for Li batteries MoS2, FeS2 and for corrosion protection RuS

    A comparative study among landraces of Phaseolus vulgaris L. and P. coccineus L. based on molecular, physicochemical and sensory analysis for authenticity purposes

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    The common and runner beans are the two most widely cultivated species because of their highly nutritive value for humans and animals. This study was undertaken to interpret data from physicochemical, sensory and molecular (DNA) analyses toward evaluating, characterizing and separating 5 common bean (Phaseolus vulgaris) and 5 runner bean (Phaseolus coccineus) landraces, cultivated under organic growing conditions. Furthermore, an attempt was made to determine patterns and interrelationships among the quality traits and sensory characteristics to get a better insight into the most effective discrimination between common and runner bean landraces, by means of multivariate analysis (Principal Component Analysis and Discriminant Analysis). In this study an accurate and effective discrimination of bean cultivars and Phaseolus species was possible using different methodologies. PCA was found to be the most informative either by using exclusively physicochemical data (92% of variability) or in conjunction with sensory data (99.4% of variability). P. vulgaris is characterized by 6 parameters (intensity, juiciness, sweetness, brightness, bitterness and consistency) whereas P. coccineus by odor, tenderness and metallic taste. Molecular analysis (MA) proved to be a fast and informative method only for discrimination of the Phaseolus species whereas (DA) highlighted the most important characteristics per cultivar and species. (C) 2012 Elsevier B.V. All rights reserved

    Genetic diversity among common bean (Phaseolus vulgaris L.) Greek landraces and commercial cultivars: nutritional components, RAPD and morphological markers

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    The genetic diversity among the main local landraces and commercial cultivars of Phaseolus vulgaris L. cultivated in Greece, was estimated by studying the morphological, agronomical and physicochemical traits along with molecular data analysis using random amplified polymorphic DNA (RAPD markers). Cluster analysis was conducted on similarity estimates using the UPGMA algorithm. Application of cluster analysis resulted in a dendrogram representing the genetic relationship among landraces and main bean cultivars grown in Greece. A wide genetic variation was observed among collected local bean landraces in morphological characteristics such as seed color, seed size and growth habit. According to agronomic performance, significant differences were found in number and weight of pods per plant. Variation in protein and fat content among landraces and commercial cultivars was also detected. Moreover, in some landraces like Kastoria and Byzitsa M/M extremely high values for protein content (28.6% and 27.0% respectively) were recorded. Such values were greater than the average protein content previously recorded for other cultivars of this species. Genetic similarity estimated from molecular analysis with RAPDs, seemed not to be related with the seed morphological characteristics and agronomic performance. Only qualitative parameters like growth habit and occasionally geographical origin of landraces were positively correlated with the molecular classification. Local bean landraces were classified in three subgroups whereas the commercial cultivars formed another separate group underlining the narrow genetic base of cultivars

    Landraces versus commercial common bean cultivars under organic growing conditions: A comparative study based on agronomic performance and physicochemical traits

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    This study targeted to assess the yield components and physicochemical traits of eight common bean landraces versus four commercial cultivars widely grown in Greece. The genotypes were cultivated for two growing seasons under organic growing conditions and a preponderance [better agronomic characteristics; number of pods per plant, seed weight, biomass and enhanced physicochemical properties; protein and fat content (%)] of landraces over commercial cultivars was found. It was also observed that organic environment of experimentation allowed for better differentiation of the examined genetic material but displayed a negative impact on the commercial cultivars. These results were obtained by determining the genetic parameters (GCV, H) and orthogonal contrasts between different (landraces versus commercial cultivars) groups according both to growth type and origin. High detectable genetic variation in agronomic performance and physicochemical traits among the examined dry bean cultivars was found. Three high yield landraces of enhanced physicochemical properties (% protein and fat content) were identified as promising material for eventual production of ecotypes endowed with high adaptation to organic cropping system
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