1-Methyl-2-[(E)-2,4,5-trimeth­oxy­styr­yl]pyridinium 4-meth­oxy­benzene­sulfonate monohydrate

In the title compound, C17H20NO3 +·C7H7O4S−·H2O, the cation exists in an E configuration with respect to the C=C bond and is twisted with a dihedral angle of 17.81 (8)° between the pyridinium and benzene rings. The benzene ring of the anion is almost parallel to the pyridinium ring [dihedral angle = 3.45 (9)°], whereas it is inclined to the benzene ring of the cation [dihedral angle = 17.62 (8)°]. The crystal structure is stabilized by O—H⋯O hydrogen bonds and weak C—H⋯O inter­actions which link the cations, anions and water mol­ecules into chains along the a axis. π–π inter­actions with centroid–centroid distances of 3.7751 (9) and 3.7920 (11) Å are also observed

The Use of Dual Energy Computerized Tomography to Detect Residual Viable Hepatocellular Carcinoma after Transarterial Chemoembolization

Objective: To determine the value of the dual energy computerized tomography (DECT) for detection of residual viable hepatocellular carcinoma (HCC) after transarterial chemoembolization (TACE).  Methods: Single-source (ss) DECT of liver was performed in adult patients who were diagnosed as HCC and treated with TACE at Siriraj Hospital during October 1st, 2013- December 31st, 2014. The diagnostic 5-point performance score of conventional liver CT imaging set (CCTI) and iodinated material density imaging set (IMDI) obtained simultaneously by using DECT, were evaluated by two radiologists. The follow up imaging at 6 months was regarded as gold standard. The sensitivity and specificity were calculated by assigned score 4 or 5 lesions as positive for the presence of HCC, assigned score 1 or 2 lesions as negative for viable tumor and assigned score 3 lesions as uncertain diagnosis. McNemar’s test was used to compare the sensitivity and specificity between CCTI and IMDI. The reading time of both technique and radiation dose were recorded and the mean reading time were compared using a paired t-test. Results: Out of total 21 patients with 66 lesions, 81% were male and 19% were female with mean age 61.8 ± 10.2 years old. After monitoring for 6 months, 35 of the total 66 lesions were still viable HCCs and 31 lesions became non-viable HCCs. CCTI had excellent inter-observer agreement while IMDI had moderate agreement (K = 0.931 and 0.534, respectively). The sensitivity of CCTI and IMDI for detection of viable tumor were 88.6% and 100%, respectively (p-value cannot be computed). The specificity of CCTI and IMDI were 96.8% and 93.5%, respectively (p-value = 1.000). The mean reading time of two radiologists for CCTI was 151.2 ± 134.7 seconds and 123.2 ± 126.8 seconds for IMDI (p-value = 0.048). Total radiation dose of dynamic liver CT was 1194.22 ± 179.44 mGy cm. Conclusion: IMDI has higher sensitivity for detection of viable HCCs after TACE and consumes less reading time than CCTI

Memory and related factors in alcohol dependent patients

This objective of this research is to study memory and related factors in alcohol dependent patients by using composite scores, immediate memory, delayed memory and total memory. The subject of this research are 62 alcohol dependent patients undergoing rehabilitation at Thanyarak Institute, Department of medical services, Ministry of Health, Pathumthani, Thailand. The researcher interviewed personal information with individual interview, screen for the depression sign by 2 Question (2Q) and assess memory by The Wechsler Memory Scale Third-Edition Abbreviated (WMS-III Abbreviated). The results revealed that average composite scores including, immediate memory and delayed memory and total memory were found to be in the borderline range. The study of individual factors with primary level education related to memory found in alcohol dependent patients had a significant difference in mean memory scores in all aspects from the other studies (p<0.05). For the age group factor, it was found those 18 - 35 years old had significant difference in mean memory scores than those 36 - 55 years old, in terms of delayed visual memory. For the nutritional factor, calculated by body mass index (BMI), it was found that those with underweight and normal weight had significant difference in mean memory scores than those who were overweight in terms of immediate visual memory (p<0.05). Nevertheless, factors associated with binge drinking, age of first exposure, duration, quantity, frequency and family history of alcohol dependence were not significant. This research showed that levels of educationare related with all modalities and memory composite while ages related to the delayed visual memory and the nutrition status related to the immediate visual memory. The other factors show no correlation between each other. There should be investigated for further study in memory including other cognitiveabilities

The Use of Dual Energy Computerized Tomography to Detect Residual Viable Hepatocellular Carcinoma after Transarterial Chemoembolization

Objective: To determine the value of the dual energy computerized tomography (DECT) for detection of residual viable hepatocellular carcinoma (HCC) after transarterial chemoembolization (TACE). Methods: Single-source (ss) DECT of liver was performed in adult patients who were diagnosed as HCC and treated with TACE at Siriraj Hospital during October 1st, 2013- December 31st, 2014. The diagnostic 5-point performance score of conventional liver CT imaging set (CCTI) and iodinated material density imaging set (IMDI) obtained simultaneously by using DECT, were evaluated by two radiologists. The follow up imaging at 6 months was regarded as gold standard. The sensitivity and specificity were calculated by assigned score 4 or 5 lesions as positive for the presence of HCC, assigned score 1 or 2 lesions as negative for viable tumor and assigned score 3 lesions as uncertain diagnosis. McNemar’s test was used to compare the sensitivity and specificity between CCTI and IMDI. The reading time of both technique and radiation dose were recorded and the mean reading time were compared using a paired t-test. Results: Out of total 21 patients with 66 lesions, 81% were male and 19% were female with mean age 61.8 ± 10.2 years old. After monitoring for 6 months, 35 of the total 66 lesions were still viable HCCs and 31 lesions became non-viable HCCs. CCTI had excellent inter-observer agreement while IMDI had moderate agreement (K = 0.931 and 0.534, respectively). The sensitivity of CCTI and IMDI for detection of viable tumor were 88.6% and 100%, respectively (p-value cannot be computed). The specificity of CCTI and IMDI were 96.8% and 93.5%, respectively (p-value = 1.000). The mean reading time of two radiologists for CCTI was 151.2 ± 134.7 seconds and 123.2 ± 126.8 seconds for IMDI (p-value = 0.048). Total radiation dose of dynamic liver CT was 1194.22 ± 179.44 mGy cm. Conclusion: IMDI has higher sensitivity for detection of viable HCCs after TACE and consumes less reading time than CCTI

Clinical and laboratory findings associated with severe scrub typhus

<p>Abstract</p> <p>Background</p> <p>Scrub typhus is a mite-borne bacterial infection of humans caused by <it>Orientia tsutsugamushi </it>that causes a generalized vasculitis that may involve the tissues of any organ system. The aim of this study was to identify factors associated to severe complications from scrub typhus.</p> <p>Methods</p> <p>We conducted this prospective, case-control study on scrub typhus patients who presented to the Department of Internal Medicine at Chosun University Hospital between September, 2004 and December, 2006. Cases were 89 scrub typhus patients with severe complications and controls were 119 scrub typhus patients without severe complications.</p> <p>Results</p> <p>There were significant differences in the absence of eschar, white blood cell (WBC) counts, hemoglobin, albumin, serum creatinine, fibrinogen, C-reactive protein (CRP), and active partial thromboplastin time (aPTT) between the two groups. Multivariate analysis demonstrated that only the following four factors were significantly associated with the severe complications of scrub typhus: (1) age ≥ 60 years (odd ratio [OR] = 3.13, <it>P </it>= 0.002, confidence interval [CI] = 1.53-6.41), (2) the absence of eschar (OR = 6.62, <it>P </it>= 0.03, CI = 1.22-35.8, (3) WBC counts > 10, 000/mm3 (OR = 3.6, <it>P </it>= 0.001, CI = 1.65-7.89), and (4) albumin ≤ 3.0 g/dL (OR = 5.01, <it>P </it>= 0.004, CI = 1.69-14.86).</p> <p>Conclusions</p> <p>Our results suggest that clinicians should be aware of the potential for complications, when scrub typhus patients are older (≥ 60 years), presents without eschar, or laboratory findings such as WBC counts > 10, 000/mm3, and serum albumin level ≤ 3.0 g/dL. Close observation and intensive care for scrub typhus patients with the potential for complications may prevent serious complications with subsequent reduction in its mortality rate.</p

ความพึงพอใจของนักศึกษาที่มีต่องานบริการการศึกษา วิทยาลัยเทคโนโลยีอุตสาหกรรมสถาบันเทคโนโลยีพระจอมเกล้าพระนครเหนือ

The research objectives aim to investigate satisfaction of students with services of Academic Service Centre, College of Industrial Technology, King Mongkut's Institute of Technology North Bangkok (KMUTNB) as well as to compare their attitudes towards three dimensions, i.e. staff, service quality, and centre facilities. A questionnaire comprising 5-scale likert and open-ended survey was distributed to 381 students enrolling in the 2008 second semester. The respondents included students in high vocational level, 2-3 year, and 4-year undergraduates. Collected data were analyzed for frequency, percentage, mean, and standard deviation. One-way ANOVA and Scheffe post hoc were applied for multiple comparison statistical procedure. As results, an overall satisfaction towards the services was found at a moderate level, similar to respondents' attitudes towards personnel, service and facilities features. Satisfaction assessment on personnel and service quality revealed no difference among student groups. On the other hand, different attitude towards centre facilities was found. In this dimension, the 2-3 year undergraduates disclosed their higher contentment than the 4-year students

คู่มือการใช้งานโฮมเพจเฟสบุ๊ค

คู่มือการใช้งานโฮมเพจเฟสบุ๊

Efficient Realization of Sigma-Delta ( <inline-formula><graphic file="1687-6180-2006-052736-i1.gif"/></inline-formula>- <inline-formula><graphic file="1687-6180-2006-052736-i2.gif"/></inline-formula>) Kalman Lowpass Filter in Hardware Using FPGA

Sigma-delta ( - ) modulation techniques have moved into mainstream applications in signal processing and have found many practical uses in areas such as high-resolution A/D, D/A conversions, voice communication, and software radio. - modulators produce a single, or few bits output resulting in hardware saving and thus making them suitable for implementation in very large scale integration (VLSI) circuits. To reduce quantization noise produced, higher-order modulators such as multiloop and multistage architectures are commonly used. The quantization noise behavior of higher-order - modulators is well understood. Based on these quantization noise characteristics, various demodulator architectures, such as filter, optimal FIR filter, and Laguerre filter are reported in literature. In this paper, theory and design of an efficient Kalman recursive demodulator filter is shown. Hardware implementation of Kalman lowpass filter, using field programmable gate array (FPGA), is explained. The FPGA synthesis results from Kalman filter design are compared with previous designs for sinc filter, optimum FIR filter, and Laguerre filter.</p