Synthesis of Cyclen-Functionalized Ethenylene-Based Periodic Mesoporous Organosilica Nanoparticles and Metal-Ion Adsorption Studies

The preparation of two cyclens both possessing two triethoxysilyl groups through click chemistry is described. These two cyclens were incorporated into bis(triethoxysilyl)ethenylene-based periodic mesoporous organosilica nanoparticles (PMO NPs) at different proportions of bis(triethoxysilyl)ethenylene/cyclens (90/10, 75/25). The obtained nanorods were analyzed with different techniques and showed high specific surface areas at low proportion of cyclens. The nanorods containing free amino groups of cyclen were then used for Ni(II) and Co(II) removal from model solutions. The kinetics and isotherms of adsorption of Ni(II) and Co(II) were determined, and the materials showed high uptake of metals (up to 3.9 mmol . g(-1)). They demonstrated pronounced selectivity in separation of rare earth elements from late transition metals, e. g. Ni(II) and Co(II) by adsorption and even more so by controlled desorption

Influence of the synthetic method on the properties of two-photon-sensitive mesoporous organosilica nanoparticles

International audienceHerein we report the modulation of the properties of mesoporous silica nanoparticles (NPs) via various synthetic approaches. Three types of elaborations were compared, one in aqueous media at 25 °C, and the other two at 80 °C in water or in a water–ethanol mixture. For all these methods, an alkoxysilylated two-photon photosensitizer (2PS) was co-condensed with tetraethylorthosilicate (TEOS) in the presence of cetyltrimethylammonium bromide (CTAB), leading to five two-photon-sensitive mesoporous silica (M2PS) NPs. The M2PS NP porous structure could be tuned from radial to worm-like and MCM-41 types of organization. Besides, the 2PS precursor spatial dispersion was found to be highly dependent on both the 2PS initial concentration and the elaboration process. As a result, two-photon properties were modulated by the choice of the synthesis, the best results being found in aqueous media at 25 or 80 °C. Finally, the M2PS NPs were used for in vitro two-photon imaging of cancer cells

Synthèses, caractérisations physico - chimiques et étude du comportement aux interfaces (solution - gaz et silice - solution) de nouveaux tensioactifs géminés cationiques à espaceur hydrophile

MONTPELLIER-BU Sciences (341722106) / SudocSudocFranceF

Synthesis and characterization of a new silica nanoparticles using APG/CTAB as modified agent

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L'or nanométrique: un agent thérapeutique

International audienceLes propriétés exceptionnelles des nanoparticules d’or en font des nanosystèmes particulièrement prometteurs pour des applications en cancérologie. Aujourd’hui, des essais cliniques évaluent d’une part l’AuroLase® pour laphotothermie, et d’autre part l’Aurimune®, des nanoparticules d’or véhiculant un agent bioactif cytotoxique. En parallèle, des recherches précliniques très actives sont conduites pour optimiser l’utilisation des nanoparticules d’or en radiothérapie anticancéreuse

From enabling technologies to medicinal mechanochemistry: an eco-friendly access to hydantoin-based active pharmaceutical ingredients

International audienceThe preparation of hydantoin scaffolds using modern non-conventional activation methods is herein described. Special attention is devoted to the preparation of hydantoin-based Active Pharmaceutical Ingredients (APIs) by mechanochemistry, highlighting its advantages compared to classical solution procedures, opening new perspectives in the sustainable preparation of useful scaffolds for the pharmaceutical industry

New and up-and-coming perspectives for an unconventional chemistry: from molecular synthesis tohybrid materials by mechanochemistry

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Accordion-shaped 10B nanostructures by sonication-assisted direct oxidation pathway for neutron sensors

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New and up-and-coming perspectives for an unconventional chemistry: from molecular synthesis tohybrid materials by mechanochemistry

International audienc

Nonionic polyoxazoline surfactants based on renewable source: Synthesis, surface and bulk properties

Abstract: The synthesis of amphiphilic lipid-polyoxazoline based on copolymers (CO-POxn) with narrow distribution has been achieved via cationic ring-opening polymerization of 2-methyl-2-oxazoline (MOx). Lipid-macroinitiator (COTs) was obtained from commercial castor oil (CO), widely renewable agricultural resource. CO-POxn with various length segments were synthesized from a macroinitiator COTs in order to investigate the effect of the length of the hydrophilic segment on the solution behavior of the nonionic polymer surfactants CO-POxn. The results showed that the critical micelle concentration rised with the increase of POx content and inversely surface tension decreased. The average size of aggregates of these structures suggested the formation of vesicles or nonspherical micelles. Star-shaped morphology of CO-POxn in solid state has also been observed using 1 environmental scanning electron microscopy (ESEM). Addionally energy dispersive X-ray (EDX) analysis demonstrated the presence of POx block in the concentric stripes of the texture