Alien Registration- Hammond, Charles (Fort Fairfield, Aroostook County)

https://digitalmaine.com/alien_docs/36347/thumbnail.jp

Neuropsychiatric complications of efavirenz in children with HIV-1 infection

Background: Efavirenz is associated with transient neuropsychiatric manifestations but the impact on neurocognition is unknown. Genetically determined black South Africans who are slow metabolizers of efavirenz may be at risk of toxicity. This study describes neuropsychiatric and neurocognitive manifestations of South African children with suspected efavirenz neurotoxicity. Method: This retrospective study describes clinical features of 12 children with suspected efavirenz neurotoxicity (2008 – 2014). Results: Twelve children were referred (aged 3 years 4 months to 12 years, mean 7 years 8 months; 8 indigenous African (black) and 4 mixed ancestry). Six had acute neuropsychiatric manifestations after 2-8 weeks (mean 5 weeks) on efavirenz including drowsiness, seizures, sleep disturbances, behavioural changes, ataxia and slurred speech. Symptoms resolved over a few weeks in four. Two black children were phenotypically slow metabolizers with high plasma efavirenz concentrations above normal range resulting in discontinuation of efavirenz. Nine children had neurocognitive concerns potentially exacerbated by long-term efavirenz (6-72 months therapy; mean 31 months), and showed poor performance in all neurocognitive domains. Conclusion: Efavirenz causes transient neuropsychiatric adverse effects and may contribute to poor longterm neurocognitive outcomes in HIV-infected children. Genetically slow metabolizers are at risk of neurotoxicity. Prospective studies comparing efavirenz-treated and efavirenz-naïve children are needed

Cupid\u27s Wings

One sunny day as Cupid lay, In rosy dreams asleep I stole his fairy wings away, And biding him a fond adieu, I quickly donned the pennons gay, That I might fly to you One sunny day as Cupid lay, In rosy dreams asleep, I stole his fairy wings away, That I might fly. That I might fly. to you

Freeholder Requirements in the Montana Code Annotated: Unconstitutional Restrictions on the Right of Political Participation

Freeholder Requirement

Hypercholesterolemia and Platelet Sensitivity to Thromb IN-Induced Aggregation in Whole Blood

A thesis presented to the faculty of the College of Arts and Sciences at Morehead State University in partial fulfillment of the requirements for the Degree of Master of Sciences in Biology by Charles E. Hammond, II on August 1, 1989

E-cigarette or Vaping Product Use Associated Lung Injury

With the increased popularity of vaping and the recognition of e-cigarette or vaping product use associated lung injury (EVALI), it is important to understand the potential harms and treatment options. A 25 year old female with acute-onset chest pain and shortness of breath. Initial workup reveals tachycardia to 140bpm but she is afebrile. Laboratory and imaging workup reveals leukocytosis and CT scan of the chest reveals a multifocal pneumonia. While in the emergent department, although not hypoxic at rest, she desaturates to 89% on room air with ambulation and is admitted to the general medical unit for CAP. On hospital day 2 she progressively becomes more dyspneic and eventually is saturating only 90% on 6L nasal cannula. At this time, upon speaking further with the patient, it is discovered that she regularly vapes marijuana for anxiety, with the last use being 6 days prior to presentation. On hospital day 3 she is intubated for acute hypoxic respiratory failure. She is paralyzed and due to being asynchronous with the ventilator and is started on steroids for EVALI treatment. She is proned on hospital day 5 to help with her oxygenation, and remains so for approximately 36 hours. On hospital day 8 she is extubated and on hospital day 9 she is transferred to the GPU on 1L nasal cannula. She is discharged home on room air on hospital day 10 and is prescribed a steroid taper for a total of 13 days of treatment. This case illustrates the potential severity and rapid progression of EVALI, as well as an effective therapeutic approach. It is important to identify EVALI early to start appropriate treatment and avoid serious respiratory decompensation.https://scholarlycommons.henryford.com/merf2020caserpt/1045/thumbnail.jp

Vapor phase growth technique of III-V compounds utilizing a preheating step

In the vapor phase epitaxy fabrication of semiconductor devices and in particular semiconductor lasers, the deposition body on which a particular layer of the laser is to be grown is preheated to a temperature about 40.degree. to 60.degree. C. lower than the temperature at which deposition occurs. It has been discovered that by preheating at this lower temperature there is reduced thermal decomposition at the deposition surface, especially for semiconductor materials such as indium gallium phosphide and gallium arsenide phosphide. A reduction in thermal decomposition reduces imperfections in the deposition body in the vicinity of the deposition surface, thereby providing a device with higher efficiency and longer lifetime

Recognizing and Responding to the Health Disparities of People with Disabilities

Health status is critically important to experiencing quality of life, self-sufficiency, and full participation in society. For the 54 million Americans with disabilities, maintaining health and wellness is especially important to reduce the impact of impairment on functioning in these critical life areas. Yet, people with disabilities may be the largest underserved subpopulation demonstrating health status disparities that stem from preventable secondary conditions. Healthy People 2010, the nation’s blueprint for improved health, addresses this problem in its objectives. In 2002 and 2005, the U.S. Surgeon General asked for public health efforts to improve the health and wellness of persons with disabilities. This article examines the concepts of health and wellness, summarizes currently available information documenting disparities in health for people with disabilities, and provides a framework for policy recommendations to reduce health disparities among people with disabilities

Partial oxidation of methane to methanol using modified mixed metal oxides

The current steam reforming process for the production of CH3OH is complicated and difficult, and therefore the direct partial oxidation of CH4 to CH3OH would be economically desirable. In previous work a design approach for a selective partial oxidation catalyst has been investigated, which comprises the combination of components with a desired reactivity, producing a successful selective partial oxidation catalyst. In this approach, it is considered a successful partial oxidation catalyst must activate methane, activate oxygen and not destroy the desired product, methanol. All these properties could not be found in a single catalyst, so it was proposed that two synergistic components could be combined, one responsible for methane activation and the other for oxygen activation/insertion. Previous work has studied the CH4/D2 exchange reaction as an indication of the ability of a metal oxide surface to activate CH4. Two metal oxides demonstrated appreciable activity for the activation of CH4, these being Ga2C3 and ZnO. These oxides were then doped with different metals in order to try and increase the activity of the catalyst. The doping of Ga2O3 with Zn or Mg did not improve the methane oxidation properties of Ga2C3, and the doping of ZnO with Ga significantly lowered the light off temperature, the temperature at which CH4 was first detected, and increased its oxidative capacity. The addition of precious metals significantly affected the catalysts ability to activate CH4. The addition of Au to the Ga and Zn catalysts dramatically reduced the light off temperature, and increased its rate of oxidation at lower temperatures, with the optimum loading 2% for both catalysts. For GaO(OH) and ZnO, the addition of 1%Au and l%Pt by coprecipitation produced a synergistic effect, producing lower light offs and higher CH4 conversion than the singly doped catalysts with Au and Pt separately. When the methane activation catalysts were combined with MoO3 in a physical mixture, a number of the mixtures produced higher methanol per pass percentage yields than its constituent parts. It is concluded that the increased methane activation properties beneficially interact with the oxygen activation and insertion properties of MoO3. However, none of the yields reported were significantly higher. A dual bed system, with the lower layer comprising the methane activation catalysts, and the upper layer consisting of MoO 3 was tested. The results for this system were promising, with the low temperature activation of CH4, combined with the oxygen insertion ability of MoO3, producing high selectivities of CH3OH at much lower temperatures. The best results were obtained when the ratio of the two layers was 50:50 with respect to 2%Au ZnO and MoO3. In previous work a design approach for a selective partial oxidation catalyst has been investigated, by combining components with a desired reactivity to produce a successful selective partial oxidation catalyst, which must activate methane and oxygen, and not destroy methanol. All these properties could not be found in a single catalyst, so it was proposed that two synergistic components could be combined, one responsible for methane activation and the other for oxygen activation/insertion. The doping of ZnO with Ga significantly lowered the light off temperature, and increased its oxidative capacity, an effect which was not seen with the doping of Ga2O3 with Zn or Mg. The addition of Au to the Ga and Zn catalysts dramatically reduced the light off temperature, and increased its rate of oxidation at lower temperatures, both with optimum loading of 2%. The addition of l%Au and l%Pt produced a synergistic effect, producing lower light offs and higher CH4 conversion than the singly doped catalysts with Au and Pt separately. When the methane activation catalysts were combined with MoO3 in a physical mixture, a number of the mixtures produced higher methanol per pass percentage yields than its constituent parts. It is concluded that the increased methane activation properties beneficially interact with the oxygen activation and insertion properties of MoO3. The dual bed system, with the lower layer comprising the methane activation catalysts, and the upper layer consisting of MoO 3 produced promising results, with the low temperature activation of CH4, combined with the oxygen insertion ability of MoO3, producing high selectivities of CH3OH at much lower temperatures. The best results were obtained when the ratio of the two layers was 50:50 with respect to 2%Au ZnO and MoO3. (Abstract shortened by UMI.).EThOS - Electronic Theses Online ServiceGBUnited Kingdo