BANA-positive plaque samples are associated with oral hygiene practices and not CD4+ T cell counts in HIV-positive patients

Background. The “red complex” microorganisms, namely, Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia are considered as potential pathogens causing HIV-associated periodontal diseases. Moreover, it has been recognized that an association exists between CD4+ T cell counts and periodontal disease progression. Objective. To establish whether CD4+ T cell counts or oral hygiene plays a greater role in producing BANA-positive results in HIV-associated periodontal disease. Materials and Methods. One hundred and twenty HIV-positive patients participated in the study, and their CD4+ T cell counts were obtained from their medical records. The six Ramfjord teeth were used for evaluating periodontal clinical indices and subgingival plaque sampling. BANA test was used for the detection and prevalence of the “red complex” bacteria in plaque samples. Results.Amajority of 69.17% HIV-positive patients were BANA-positive. No significant associations were found between BANA and CD4+ T cell counts. A highly significant association was found between BANA with probing depth and clinical attachment level (P ≤ 0.0001) and between BANA and the use of interdental aids (P = 0.0168). Conclusion. HIV-associated periodontal diseases are strongly related to oral hygiene practices rather than the effect of CD4+ T cell counts, and the use of interdental aids was marked as a significant predictor of BANA-negative plaque samples.National Research Foundation of South Afric

Appropriate Methodologies to Better Measure Consumer Preferences for Postal Services

This report summarises work undertaken testing the use of stated preference discrete choice experiments to measure consumer preferences for postal services. It discusses the importance of understanding and quantifying consumer priorities in the postal sector and presents different methods used for valuing non-market goods. We recommend the use of stated preference discrete choice experiments, and test the use of this approach in three member states. We provide the findings for these member states, as well as a “tool kit” for applying this methodology in other member states in future.Consumer preferences, postal services, discrete choice, two-sided market

Is human Immunodeficiency Virus (HIV) stage an independent risk factor for altering the periodontal status of HIV-positive patients? A South African study

Background: The immunosuppresion in HIV patients makes them highly susceptible to microbial infections. The aim of the study was to establish whether HIV stage (as depicted by CD4+ T lymphocyte counts) could independently be associated with periodontal status (as revealed by the measurement of clinical indices). Methods: One hundred and twenty HIV-infected patients attending an infectious diseases clinic in the Western Cape, South Africa were included in the study. The periodontal clinical indices such as plaque index, gingival index, pocket probing depth and clinical attachment levels were measured on the mesial aspect of the six Ramfjord teeth. The CD4 + T cell counts were taken from the patients’ medical records and patients’ HIV stage determined and grouped according to their CD4+ T cell counts into A (500 cells /mm3). Results: The mean age of 120 HIV-positive patients was 33.25 years and the mean CD4 + T cell count was 293.43 cells/mm3. The probing depth and clinical attachment loss were found to be significantly associated with the total CD4 + T cell counts but not with HIV stage. Significant correlations were found between age and all clinical indices except for clinical attachment loss. No correlation was found between age and HIV stage of the patients. The use of antiretroviral therapy was significantly associated with probing depth and clinical attachment loss, but not with plaque nor gingival index. Significant associations were observed between smoking and all of the clinical indices except for the gingival index. A significant association was observed between the use of interdental aids and all the clinical indices except for probing depth, while brushing was significantly associated with plaque index only. CD4 + T cell counts were significantly associated with brushing frequency (p = 0.0190) and the use of interdental aids (p = 0.0170). Conclusion: The findings of this study conclude that HIV stage, ART and age are not independent risk factors for changes in the periodontal status of HIV-positive subjects but rather that smoking and oral hygiene habits determine their susceptibility to disease.National Research Foundatio

Health worker migration in Canada: Histories, geographies, and ethics (Working paper number 12-02)

This working paper explores issues of health worker migration through examining the history, geography, and ethics of international recruitment and migration of health workers to Canada, focusing on the experiences of registered nurses from the Philippines. During the past few decades the migration of Filipino nurses to Canada has considerably expanded, with nurses from the Philippines making up the largest group of all immigrant nurses in the Canadian workforce. Derived from presentations, discussions, and insights from an interdisciplinary workshop on health worker migration attended by academics, professionals, policymakers and health workers, we underscore the importance of further debate on the issues confronting recent migrant nurses from the Philippines to Canada. The aim of this working paper is to bring the complexity of the experiences of migrating nurses in health care explored during the workshop through various lenses of transnational historical research and biographical reflection, contextual and local geographical studies, evolving ethical norms and policies guidelines around recruitment, national and internationally, to a wider audience. We call for more in-depth academic research engaging the perspectives of policymakers and health professionals and of migrant nurses affected by their decisions. Furthermore, we bring forward recommendations and insights raised during the workshop

An in-vitro analysis of the antimicrobial efficacy of herbal toothpastes on selected primary plaque colonizers

Plaque associated oral disease affects a considerable portion of the population and is considered one of the major causes of tooth loss. In most cases toothbrushing only removes a limited amount of dental plaque and other chemical agents are required to reduce the bacterial load. Aims & objectives: The purpose of study was to determine whether there was any significant difference in the antimicrobial activity of 4 herbal toothpastes against cultures of 3 primary plaque colonizers. Methods: A total of 5 toothpastes were tested for their antimicrobial efficacy against Streptococcus mutans (NCTC 10920), Streptococcus sanguinis (NCTC 10904) and a non-specific α-heamolytic streptococcus by agar diffusion method. The data were collected and analysed using one way ANOVA and Tukey’s multiple comparison test significant at p<0.05. Results: Dentazyme® herbal toothpaste showed the greatest ability to inhibit bacterial growth for all the tested organisms (p<0.05). Nature Fresh had the lowest potential for antimicrobial activity. Conclusions: Dentazyme® Herbal toothpaste was the only herbal toothpaste to inhibit the growth of all the bacteria tested and had similar antimicrobial efficacy to a triclosan containing toothpaste (Colgate® Total®)

An in-vitro analysis of the antimicrobial efficacy of herbal toothpastes on selected primary plaque colonizers

Plaque associated oral disease affects a considerable portion of the population and is considered one of the major causes of tooth loss. In most cases toothbrushing only removes a limited amount of dental plaque and other chemical agents are required to reduce the bacterial load. Aims &amp; objectives: The purpose of study was to determine whether there was any significant difference in the antimicrobial activity of 4 herbal toothpastes against cultures of 3 primary plaque colonizers. Methods: A total of 5 toothpastes were tested for their antimicrobial efficacy against Streptococcus mutans (NCTC 10920), Streptococcus sanguinis (NCTC 10904) and a non-specific &alpha;-heamolytic streptococcus by agar diffusion method. The data was collected and analysed using one way ANOVA and Tukey&rsquo;s multiple comparison test significant at p&lt;0.05. Results: Dentazyme&reg; Herbal toothpaste showed the greatest ability to inhibit bacterial growth for all the test organisms (p&lt;0.05). Nature Fresh had the lowest potential for antimicrobial activity. Conclusions: Dentazyme&reg; Herbal toothpaste was the only herbal toothpaste to inhibit the growth of all the bacteria tested and had similar antimicrobial efficacy to a triclosan containing toothpaste (Colgate&reg; Total&reg;)

Systematic Review on the Management of Chronic Constipation in North America

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72642/1/j.1572-0241.2005.50613_2.x.pd

Fatal rodentborne leptospirosis in prison inmates, South Africa, 2015

This work was supported by a Royal Society for Tropical Medicine and Hygiene small grant (grant no. GR000556) and by a Biotechnology and Biological Sciences Research Council EastBIO DTP award (grant no. BB/M010996/1 to M.M.).Peer reviewedPublisher PD

Familial Recurrence of Cerebral Palsy with Multiple Risk Factors

The recurrence of cerebral palsy in the same family is uncommon. We, however, report on two families with two or more affected siblings. In both families, numerous potential risk factors were identified including environmental, obstetric, and possible maternal effects. We hypothesize that multiple risk factors may lead to the increased risk of recurrence of cerebral palsy in families. Intrinsic and maternal risk factors should be investigated in all cases of cerebral palsy to properly counsel families on the risk of recurrence. Recent studies of genetic polymorphisms associated with cerebral palsy are considered with reference to our observations in these two families

Is human immunodeficiency virus (HIV) stage an independent risk factor for altering the periodontal status of HIV-positive patients? A South African study

The immunosuppresion in HIV patients makes them highly susceptible to microbial infections. The aim of the study was to establish whether HIV stage (as depicted by CD4+ T lymphocyte counts) could independently be associated with periodontal status (as revealed by the measurement of clinical indices). One hundred and twenty HIV-infected patients attending an infectious diseases clinic in the Western Cape, South Africa were included in the study. The periodontal clinical indices such as plaque index, gingival index, pocket probing depth and clinical attachment levels were measured on the mesial aspect of the six Ramfjord teeth. The CD4 + T cell counts were taken from the patients’ medical records and patients’ HIV stage determined and grouped according to their CD4+ T cell counts into A (<200 cells /mm3 ), B (200–500 cells /mm3 ) and C (>500 cells /mm3 )