32 research outputs found
Do echo-enhanced needles improve time to cannulate in a model of short-axis ultrasound-guided vascular access for a group of mostly inexperienced ultrasound users?
Tomographic renal cortical scintigraphy: Correlation with intravenous urography, computed tomography, ultrasonography, angiography, and nuclear magnetic resonance imaging
This study evaluates single-photon renal tomoscintigraphy (SPECT) in the evaluation of renal masses and correlates this modality, where indicated, with computed tomography (CT), ultrasonography (US), angiography (ANGIO) and nuclear magnetic resonance imaging (NMR). Eight patients with renal cortical lesions detected on intravenous urography (IVP) were evaluated by SPECT and planar nuclear imaging using Tc-99m glucoheptonate (GH). Three of these patients were felt particularly likely to have renal tumors and were additionally evaluated with US, CT, ANGIO and NMR. The five patients with nodules on IVP that were not particularly suggestive of malignancy had functioning, benign, renal tissue accounting for their IVP lesions. Four of five were found by planar-GH nuclear imaging, five/five by SPECT-GH. In addition, SPECT-GH allowed better “confidence” in the normal renal tissue diagnosis in three/five cases. Of the three renal lesions that were highly suggestive of malignancy, two were hypernephromas and one was hypertrophied functioning cortical tissue. All three were correctly identified prospectively on SPECT-GH; however, one hypernephroma was missed on planar-GH. NMR, CT, and ANGIO detected only one of two hypernephromas prospectively (US detected both); all four modalities incorrectly diagnosed the hypertrophied tissue suggestive of malignancy.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/46822/1/259_2004_Article_BF00279072.pd
Zebrafish hoxd4a Acts Upstream of meis1.1 to Direct Vasculogenesis, Angiogenesis and Hematopoiesis
10.1371/journal.pone.0058857PLoS ONE83
De Novo Renal Tumors Arising in Kidney Transplants: Midterm Outcome after Percutaneous Thermal Ablation
Percutaneous image-guided radiofrequency ablation of painful metastases involving bone: a multicenter study.
Purpose
Few options are available for pain relief in patients with bone metastases who fail standard treatments.
We sought to determine the benefit of radiofrequency ablation (RFA) in providing pain relief for patients
with refractory pain secondary to metastases involving bone.
Patients and Methods
Thirty-one US and 12 European patients with painful osteolytic metastases involving bone were treated
with image-guided RFA using a multitip needle. Treated patients had
4/10 pain and had either failed
or were poor candidates for standard treatments such as radiation or opioid analgesics. Using the Brief
Pain Inventory–Short Form, worst pain intensity was the primary end point, with a 2-unit drop considered
clinically significant.
Results
Forty-three patients were treated (median follow-up, 16 weeks). Before RFA, the mean score for worst
pain was 7.9 (range, 4/10 to 10/10). Four, 12, and 24 weeks following treatment, worst pain decreasedto 4.5 (P0001), 3.0 (P
0001), and 1.4 (ìP.0005), respectively. Ninety-five percent (41 of 43
patients) experienced a decrease in pain that was considered clinically significant. Opioid usage
significantly decreased at weeks 8 and 12. Adverse events were seen in 3 patients and included (1) a
second-degree skin burn at the grounding pad site, (2) transient bowel and bladder incontinence
following treatment of a metastasis involving the sacrum, and (3) a fracture of the acetabulum following
RFA of an acetabular lesion.
Conclusion
RFA of painful osteolytic metastases provides significant pain relief for cancer patients who have failed
standard treatment