27,124 research outputs found
Mathematical models of avascular cancer
This review will outline a number of illustrative mathematical models describing the growth of avascular tumours. The aim of the review is to provide a relatively comprehensive list of existing models in this area and discuss several representative models in greater detail. In the latter part of the review, some possible future avenues of mathematical modelling of avascular tumour development are outlined together with a list of key questions
Mathematical models of avascular cancer
This review will outline a number of illustrative mathematical models describing the growth of avascular tumours. The aim of the review is to provide a relatively comprehensive list of existing models in this area and discuss several representative models in greater detail. In the latter part of the review, some possible future avenues of mathematical modelling of avascular tumour development are outlined together with a list of key questions
Analysis of Brownian Dynamics Simulations of Reversible Bimolecular Reactions
A class of Brownian dynamics algorithms for stochastic reaction-diffusion
models which include reversible bimolecular reactions is presented and
analyzed. The method is a generalization of the --\newrho model for
irreversible bimolecular reactions which was introduced in [arXiv:0903.1298].
The formulae relating the experimentally measurable quantities (reaction rate
constants and diffusion constants) with the algorithm parameters are derived.
The probability of geminate recombination is also investigated.Comment: 16 pages, 13 figures, submitted to SIAM Appl Mat
Analysis of Brownian dynamics simulations of reversible biomolecular reactions
A class of Brownian dynamics algorithms for stochastic reaction-diffusion models which include reversible bimolecular reactions is presented and analyzed. The method is a generalization of the λ-rho model for irreversible bimolecular reactions which was introduced in [11]. The formulae relating the experimentally measurable quantities (reaction rate constants and diffusion constants) with the algorithm parameters are derived. The probability of geminate recombination is also investigated
Squeezing out the last 1 nanometer of water: A detailed nanomechanical study
In this study, we present a detailed analysis of the squeeze-out dynamics of
nanoconfined water confined between two hydrophilic surfaces measured by
small-amplitude dynamic atomic force microscopy (AFM). Explicitly considering
the instantaneous tip-surface separation during squeezeout, we confirm the
existence of an adsorbed molecular water layer on mica and at least two
hydration layers. We also confirm the previous observation of a sharp
transition in the viscoelastic response of the nanoconfined water as the
compression rate is increased beyond a critical value (previously determined to
be about 0.8 nm/s). We find that below the critical value, the tip passes
smoothly through the molecular layers of the film, while above the critical
speed, the tip encounters "pinning" at separations where the film is able to
temporarily order. Pre-ordering of the film is accompanied by increased force
fluctuations, which lead to increased damping preceding a peak in the film
stiffness once ordering is completed. We analyze the data using both
Kelvin-Voigt and Maxwell viscoelastic models. This provides a complementary
picture of the viscoelastic response of the confined water film
Asymptotic analysis of a secondary bifurcation of the one-dimensional Ginzburg-Landau equations of superconductivity
The bifurcation of asymmetric superconducting solutions from the normal solution is considered for the one-dimensional Ginzburg--Landau equations by the methods of formal asymptotics. The behavior of the bifurcating branch depends on the parameters d, the size of the superconducting slab, and , the Ginzburg--Landau parameter. The secondary bifurcation in which the asymmetric solution branches reconnect with the symmetric solution branch is studied for values of for which it is close to the primary bifurcation from the normal state. These values of form a curve in the -plane, which is determined. At one point on this curve, called the quintuple point, the primary bifurcations switch from being subcritical to supercritical, requiring a separate analysis. The results answer some of the conjectures of [A. Aftalion and W. C. Troy, Phys. D, 132 (1999), pp. 214--232]
Analytical and experimental investigations of low level acceleration measurement techniques
Construction techniques for accelerometer with low level threshold sensitivit
The School Improvement Partnership Programme: Using Collaboration and Enquiry to tackle Educational Inequity
No abstract available
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