Additional file 1: Figure S1. of Ternary cocktail nanoparticles for sequential chemo-photodynamic therapy

Cumulative MB release of (a) NPsmall, (c) NPbig&thin, and (e) NPbig&thick and hour-by-hour MB release profiles of (b) NPsmall, (d) NPbig&thin, and (f) NPbig&thick, from PBS buffer at 37 °C. Figure S2. Silica content of Panc-1 cells presented in percentages after 6, 18, and 24 hrs incubation with cocktail nanoparticles. Figure S3. IC50 determination of free GM and DTX treatment groups in 4 different cell lines. Figure S4. Cytotoxicity evaluation of NPsmall, NPbig&thin and NPbig&thick in 4 different cells. Figure S5. Cytotoxicity evaluation of Cocktail NPs. Figure S6. The tumor size growth curves during the treatment in (a) AsPC-1 cells, (b) BxPC-3 cells, (c) MIA PaCa-2 cells and (d) Panc-1 cells. Figure S7. The bio-distribution of cocktail NPs presented by Silica percentage in (a) AsPC-1, (b) Panc-1, (c) MIA PaCa-2 and (d) BxPC-3 tumors bearing mice. Table S1-S4. Statistical analysis of tumor weight treated with Cocktail NPs upon different irradiation protocols in AsPC-1, BxPC-3, MIA PaCa-2 and Panc-1 tumor model. (DOCX 1397 kb

Additional file 1: of Negatively charged AuNP modified with monoclonal antibody against novel tumor antigen FAT1 for tumor targeting

Supplementary figures. (DOC 2242 kb