Pityriasis lichenoid-like mycosis fungoides in a 9-year-old boy: A case report

No abstract availabl

Lichen Simplex Chronicus Associated With Erectile Dysfunction: A Population-Based Retrospective Cohort Study.

An association between lichen simplex chronicus (LSC) and sexual dysfunction was explored. However, no data are available from investigations into the relationship between erectile dysfunction (ED) and LSC.This retrospective population-based cohort study aimed to clarify the risk of ED associated with LSC.By using the Taiwan National Health Insurance Research dataset, we identified 5611 male patients who had been newly diagnosed with LSC from 2000 to 2004. The date of diagnosis was identified as the index date. LSC patients with incomplete demographic information or with a history of ED before the index date were excluded. In total, 22444 age-matched patients without LSC were randomly selected as the non-LSC group based on a 1:4 ratio. Subsequence occurrence of ED was measured until 2011. The association between LSC and the risk of developing ED was estimated using Cox proportional hazard regression model.After adjusting for age and comorbidities, patients with LSC had a 1.74-fold greater risk of developing ED compared with those without LSC (95% confidence interval=1.44-2.10). LSC patients with comorbidities including diabetes, hyperlipidemia, hypertension, cardiovascular disease, peripheral arterial disease, chronic obstructive pulmonary disease, chronic kidney disease, depression, and anxiety were at a higher risk of ED compared with the non-LSC patients without comorbidities.LSC confers a greater risk in the development of ED. Physicians should be aware of the potential of ED occurrence in LSC patients

Incidence rates and hazard ratio for erectile dysfunction risk stratified by the severity of lichen simplex chronicus.

<p>Abbreviation: LSC, lichen simplex chronicus; IR, incidence rates, per 1,000 person-years; HR, hazard ratio; CI, confidence interval.</p><p>^† Adjusted for age and comorbidity in Cox proportional hazards regression.</p><p>*** p<0.001.</p><p>Incidence rates and hazard ratio for erectile dysfunction risk stratified by the severity of lichen simplex chronicus.</p

Cox Proportional Hazard Regression Analysis for the risk of erectile dysfunction-associated lichen simplex chronicus with joint effect of comorbidity.

<p>Abbreviation: LSC, lichen simplex chronicus; IR, incidence rate, per 1,000 person-years; HR, hazard ratio; CI, confidence interval; DM, diabetes mellitus; CVD, cardiovascular disease; PAD, peripheral arterial disease; COPD, chronic obstructive pulmonary disease; CKD, chronic kidney disease.</p><p>^† Adjusted for age.</p><p>* p<0.05,</p><p>** p<0.01,</p><p>*** p<0.001</p><p>Cox Proportional Hazard Regression Analysis for the risk of erectile dysfunction-associated lichen simplex chronicus with joint effect of comorbidity.</p

Incidence rates and hazard ratio for erectile dysfunction according to lichen simplex chronicus (LSC) status stratified by age and comorbidity status.

<p>Abbreviation: LSC, lichen simplex chronicus; IR, incidence rate, per 1,000 person-years; HR, hazard ratio; CI, confidence interval; ED, erectile dysfunction.</p><p>^† Mutually adjusted for age and comorbidity in Cox proportional hazards regression</p><p>^‡ Patients with any one of diabetes mellitus, hyperlipidemia, hypertension, cardiovascular disease, stroke, peripheral arterial disease, chronic obstructive pulmonary disease, chronic kidney disease, depression, and anxiety were classified as the comorbidity group</p><p>* p<0.05,</p><p>** p<0.01,</p><p>*** p<0.001</p><p>Incidence rates and hazard ratio for erectile dysfunction according to lichen simplex chronicus (LSC) status stratified by age and comorbidity status.</p

Cumulative incidence curves of ED for LSC and non-LSC groups.

<p>Abbreviation: LSC, lichen simplex chronicus; ED, erectile dysfunction.</p

Association between inflammatory bowel disease and bullous pemphigoid: a population-based case–control study

Abstract The coexistence of inflammatory bowel disease (IBD) and bullous pemphigoid (BP) has been reported. No large-scale study to date has explored the relationship between these diseases. This population-based case-control study examined the association between IBD and BP by using a nationwide database. A total of 5,263 BP patients and 21,052 age- and gender-, hospital visit number-matched controls were identified in the National Health Insurance Research Database of Taiwan (1997–2013). Demographic characteristics and comorbidities including IBD were compared. Logistic regression was conducted to examine the predicting factors for BP. The mean age at diagnosis was 74.88 years and 54.3% of subjects were male. BP patients tended to have more cardiovascular risk factors, autoimmune and neurologic comorbidities, and hematologic cancers than matched controls. There were 20 cases of IBD (0.38%), mostly ulcerative colitis (N = 17, 0.32%) among BP patients, compared to 33 IBD cases (0.16%) among controls (p < 0.001). Ulcerative colitis was found to be significantly associated with BP [adjusted odds ratio (OR) 3.60, 95% confidence interval (CI) 1.91–6.77, p < 0.001] on multivariate analysis. Treatment for IBD was not associated with BP development. Information about diet, lifestyle, alcohol consumption, and smoking habit was not available. We concluded that UC is independently associated with BP