Genera (relative abundance>1% at genus levels) in the initial inoculum and the samples of the top, middle and bottom layers.

<p>The dominant genera in the different layers are shown in bold.</p

Venn diagram illustrating the overlap of the four bacterial communities from the initial inoculum and the samples of the top, middle and bottom layers.

<p>The shared OTUs (69) were analysed at the phylum level.</p

Microbial Community in a Biofilter for Removal of Low Load Nitrobenzene Waste Gas - Fig 5

<p><b>Principal component analysis (PCA) of bacterial communities from the initial inoculum and samples of the top, middle and bottom layers based on the classified OTUs (a)</b>. <b>Heat map illustrating the abundances of all the major genera (with a relative abundance of more than 1% in at least one sample).</b> The color intensity (log scale) in each panel indicates the relative abundance of the genus in each sample (b).</p

Concentrations of nitrite released.

<p>Concentrations of nitrite released.</p

The packing parameters.

<p>The packing parameters.</p

Abundances and distributions of the different phyla in the four biofilm samples.

<p>Abundances and distributions of the different phyla in the four biofilm samples.</p

Prediction of Adsorption Equilibrium of VOCs onto Hyper-Cross-Linked Polymeric Resin at Environmentally Relevant Temperatures and Concentrations Using Inverse Gas Chromatography

Hyper-cross-linked polymeric resin (HPR) represents a class of predominantly microporous adsorbents and has good adsorption performance toward VOCs. However, adsorption equilibrium of VOCs onto HPR are limited. In this research, a novel method for predicting adsorption capacities of VOCs on HPR at environmentally relevant temperatures and concentrations using inverse gas chromatography data was proposed. Adsorption equilibrium of six VOCs (<i>n</i>-pentane, <i>n</i>-hexane, dichloromethane, acetone, benzene, 1, 2-dichloroethane) onto HPR in the temperature range of 403–443 K were measured by inverse gas chromatography (IGC). Adsorption capacities at environmentally relevant temperatures (293–328 K) and concentrations (<i>P</i>/<i>P</i>_s = 0.1–0.7) were predicted using Dubinin–Radushkevich (DR) equation based on Polany’s theory. Taking consideration of the swelling properties of HPR, the volume swelling ratio (<i>r</i>) was introduced and <i>r</i>·<i>V</i>_micro was used instead of <i>V</i>_micro determined by N₂ adsorption data at 77 K as the parameter <i>q</i>₀ (limiting micropore volume) of the DR equation. The results showed that the adsorption capacities of VOCs at environmentally relevant temperatures and concentrations can be predicted effectively using IGC data, the root-mean-square errors between the predicted and experimental data was below 9.63%. The results are meaningful because they allow accurate prediction of adsorption capacities of adsorbents more quickly and conveniently using IGC data

A Phenotypic Cell-Binding Screen Identifies a Novel Compound Targeting Triple-Negative Breast Cancer

We describe a “phenotypic cell-binding screen” by which therapeutic candidate targeting cancer cells of a particular phenotype can be isolated without knowledge of drug targets. Chemical library beads are incubated with cancer cells of the phenotype of interest in the presence of cancer cells lacking the phenotype of interest, and then the beads bound to only cancer cells of the phenotype of interest are selected as hits. We have applied this screening strategy in discovering a novel compound (LC129-8) targeting triple-negative breast cancer (TNBC). LC129-8 displayed highly specific binding to TNBC in cancer cell lines and patient-derived tumor tissues. LC129-8 exerted anti-TNBC activity by inducing apoptosis, inhibiting proliferation, reversing epithelial-mesenchymal transition, downregulating cancer stem cell activity and blocking in vivo tumor growth

Functionalization of Azacalixaromatics by Cu(II)-Catalyzed Oxidative Cross-Coupling Reaction between the Arene C–H Bond and Boronic Acids

Catalyzed by Cu­(ClO₄)₂·6H₂O under mild aerobic conditions using air as the oxidant, azacalix[1]­arene[3]­pyridines underwent a highly efficient oxidative cross-coupling reaction with a large number of aryl-, alkenyl-, and alkylboronic acids to afford diverse functionalized macrocycles. Stoichiometric reactions of an arylboronic acid with isolated and structurally well-defined high valent organocopper compounds indicated the involvement of arylcopper­(II) rather than arylcopper­(III) species as an organometallic intermediate in catalysis

Schematic representation of the experimental setup.

<p>Schematic representation of the experimental setup.</p