Low-complexity iterative frequency domain decision feedback equalization

Single-carrier transmission with frequency domain equalization (SC-FDE) offers a viable design alternative to the classic orthogonal frequency division multiplexing technique. However, SC-FDE using a linear equalizer may suffer from serious performance deterioration for transmission over severely frequency-selective fading channels. An effective method of solving this problem is to introduce non-linear decision feedback equalization (DFE) to SC-FDE. In this contribution, a low complexity iterative decision feedback equalizer operating in the frequency domain of single-carrier systems is proposed. Based on the minimum mean square error criterion, a simplified parameter estimation method is introduced to calculate the coefficients of the feed-forward and feedback filters, which significantly reduces the implementation complexity of the equalizer. Simulation results show that the performance of the proposed simplified design is similar to the traditional iterative block DFE under various multipath fading channels but it imposes a much lower complexity than the latter

Loss of ATF3 exacerbates liver damage through the activation of mTOR/p70S6K/ HIF-1α signaling pathway in liver inflammatory injury.

Activating transcription factor 3 (ATF3) is a stress-induced transcription factor that plays important roles in regulating immune and metabolic homeostasis. Activation of the mechanistic target of rapamycin (mTOR) and hypoxia-inducible factor (HIF) transcription factors are crucial for the regulation of immune cell function. Here, we investigated the mechanism by which the ATF3/mTOR/HIF-1 axis regulates immune responses in a liver ischemia/reperfusion injury (IRI) model. Deletion of ATF3 exacerbated liver damage, as evidenced by increased levels of serum ALT, intrahepatic macrophage/neutrophil trafficking, hepatocellular apoptosis, and the upregulation of pro-inflammatory mediators. ATF3 deficiency promoted mTOR and p70S6K phosphorylation, activated high mobility group box 1 (HMGB1) and TLR4, inhibited prolyl-hydroxylase 1 (PHD1), and increased HIF-1α activity, leading to Foxp3 downregulation and RORγt and IL-17A upregulation in IRI livers. Blocking mTOR or p70S6K in ATF3 knockout (KO) mice or bone marrow-derived macrophages (BMMs) downregulated HMGB1, TLR4, and HIF-1α and upregulated PHD1, increasing Foxp3 and decreasing IL-17A levels in vitro. Silencing of HIF-1α in ATF3 KO mice ameliorated IRI-induced liver damage in parallel with the downregulation of IL-17A in ATF3-deficient mice. These findings demonstrated that ATF3 deficiency activated mTOR/p70S6K/HIF-1α signaling, which was crucial for the modulation of TLR4-driven inflammatory responses and T cell development. The present study provides potential therapeutic targets for the treatment of liver IRI followed by liver transplantation

Dipolar Rydberg-atom gas prepared by adiabatic passage through an avoided crossing

The passage of cold cesium 49S$_{1/2}$ Rydberg atoms through an electric-field-induced multi-level avoided crossing with nearby hydrogen-like Rydberg levels is employed to prepare a cold, dipolar Rydberg atom gas. When the electric field is ramped through the avoided crossing on time scales on the order of 100~ns or slower, the 49S$_{1/2}$ population adiabatically transitions into high-\emph{l} Rydberg Stark states. The adiabatic state transformation results in a cold gas of Rydberg atoms with large electric dipole moments. After a waiting time of about $1~\mu$s and at sufficient atom density, the adiabatically transformed highly dipolar atoms become undetectable, enabling us to discern adiabatic from diabatic passage behavior through the avoided crossing. We attribute the state-selectivity to $m$-mixing collisions between the dipolar atoms. The data interpretation is supported by numerical simulations of the passage dynamics and of binary $m$-mixing collisions.Comment: 9 pages, 6 figure

Coculture of stem cells from apical papilla and human umbilical vein endothelial cell under hypoxia increases the formation of three-dimensional vessel-like structures in vitro

published_or_final_versio

An Efficient Imaging Strategy for Single Pixel Camera in Earth Observation

Single pixel camera is a new imaging device that develops from the “ghost” imaging and compressive sensing theory. For high resolution imaging with large amount of data, the process of measurement and reconstruction is time-consuming, which limits its application to remote sensing area. Based on the analysis of the configuration of the single pixel camera, an efficient imaging strategy through combining different numbers of DMD mirrors and local imaging was proposed which is able to image the interested target in high resolution with low time cost. Simulation experiment was carried out for two different types of targets, i.e., three-line target image and the scene consisting of a ship in the ocean. Three types of images, in low, middle and high resolution, are reconstructed respectively by the control of DMD working area and the strategy to combining DMD mirrors. The reconstructed images reached the application requirements at very low measurement and reconstruction time cost. The effectiveness and practicality of this strategy could be applied to other compressive sensing imaging devices