451 research outputs found
水系リチウムイオンおよびカルシウムイオン電池用正極の電気化学特性に関する研究
京都大学新制・課程博士博士(工学)甲第23515号工博第4927号新制||工||1769(附属図書館)京都大学大学院工学研究科物質エネルギー化学専攻(主査)教授 安部 武志, 教授 陰山 洋, 教授 作花 哲夫学位規則第4条第1項該当Doctor of Philosophy (Engineering)Kyoto UniversityDFA
Extracellular signal-regulated kinase (ERK) activation is required for porcine epidemic diarrhea virus replication
AbstractPorcine epidemic diarrhea virus (PEDV) is a highly enteropathogenic coronavirus of swine that causes acute enteritis with high mortality in nursery piglets. To date, the cellular factors involved in PEDV replication have not been well defined. The extracellular signal-regulated kinase (ERK) that serves as a critical component of cellular signal transduction pathways to modulate a variety of cellular functions has been shown to regulate several viral infections. In the present study, we found that PEDV activates ERK1/2 early in infection independently of viral replication. The PEDV-induced ERK1/2 activation resulted in the phosphorylation of its downstream substrate Elk-1 in infected cells. Treatment with ERK inhibitors or ERK1/2 knockdown significantly suppressed viral progeny production. Inhibition of ERK activation also diminished viral protein expression and genomic and subgenomic RNA transcription. These findings indicate that the ERK signaling pathway plays an important role in the PEDV life cycle and beneficially contributes to viral infection
Linear optical response from the odd parity Bardasis-Schrieffer mode in locally non-centrosymmetric superconductors
On the recent report of a magnetic field induced first order transition
between an even-parity superconductivity and an odd-parity superconductivity in
, the microscopic physics is still under
investigation. However, if, in the vicinity of this transition, the coupling
strengths of the even and odd pairing channels are comparable, a
particle-particle excitonic collective mode referred to as the
Bardasis-Schrieffer (BS) mode should generically exist below the pair-breaking
continuum. This BS mode can couple to the light and thus affect the optical
response of the superconductor, as it arises from a pairing channel with the
parity opposite to that of the ground state pairs. Here, by using a generic
bilayer model Hamiltonian for the electronic degree of freedom, which is
globally centrosymmetric despite each layer being locally non-centrosymmetric,
we study the change of the excitation gap of the BS mode with respect to the
out-of-plane magnetic fields and demonstrate that its coupling to the light is
possible even in the linear response regime. The linear coupling is attributed
to the presence of multiple electronic bands, which is a generic feature of a
bilayer system. Our result shows the microwave absorption as the signature of
the BS mode, and hence a smoking gun signature of the parity-switching at the
transition between two superconducting phases.Comment: 17 pages, 7 figures, 1 tabl
Electroluminescence properties of organic light-emitting diodes with a red dye doped into Alq3:rubrene mixed Host
We have studied the electroluminescence (EL) properties of devices with a red fluorescent dye, 4-(dicyanomethylene)-2-t-butyl-6-(1,1,7,7-tetramethyljulolidyl-9-enyl)-4H-pyran (DCJTB), doped into a mixed matrix of tris-(8-hydroxyquinoline)aluminum (Alq) and rubrene. The devices doped with DCJTB in the Alq:rubrene mixed host show an efficient red emission from DCJTB with negligible EL emission from both Alq and rubrene. The QE increases with increasing rubrene concentration and reaches a maximum of about 3.6 % for a DCJTB doping concentration of about 5 % in the Alq:rubrene mixed (50:50 % ratio by weight) host, and then decreases at higher rubrene concentration, due to the concentration quenching effect. At a given bias voltage, the current density increases with increasing rubrene doping concentration, but it decreases with increasing DCJTB doping concentration. The results imply that the injected electrons and holes can transport via hopping through the energy levels of rubrene molecules while DCJTB acts as traps
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