4,096 research outputs found
Studies on Utilizing the Three Famous International Index Systems to Evaluate Scientific Research Level of Higher Learning Institutions
Science Citation Index (SCI), The Engineering Index (EI) and Index to Scientific & Technical Proceeding (ISTP) are widely accepted and used to evaluate the scientific research level of higher learning institutions by many country's science and technology field currently. After research, we point out the blemishes in this method and put forward the problems that need to be noticed, and then, under current conditions, bring forward brand-new standard and method to estimate research level, efficiency, fund exploitation and so on. One shouldn't over-emphasize the total amount of papers collected in SCI, EI & ISTP when evaluating the scientific research level of higher learning institutions, whereas using ‘comprehensive factor’ analysis method can make it more scientific and efficient
On the masses of light pseudoscalar mesons
We investigate the masses of light pseudoscalar mesons by the method based on
a new anomaly free condition for axial vector current. By this viewpoint, the
field theories discussed here do not have the problem. We calculate the
masses of nine light pseudoscalar mesons, with theoretical result agrees
reasonably good with experiment.Comment: 22 pages, 9 figure
Bioadhesive drug delivery system of diltiazem hydrochloride for improved bioavailability in cardiac therapy
Purpose: To prepare and evaluate bioadhesive buccal films of diltiazem hydrochloride (a L-type calcium channel blocker) for overcoming the limitations of frequent dosing, low bioavailability and gastrointestinal discomfort of oral delivery.Methods: Buccal films were prepared by solvent casting technique using sodiumcarboxymethylcellulose, polyvinyl pyrrolidone K-30 and polyvinyl alcohol. The films were evaluated for weight, thickness, surface pH, swelling index, in vitro residence time, folding endurance, in vitro release, ex-vivo permeation (across porcine buccal mucosa) and drug content uniformity.Results: The drug content of the formulations was uniform with a range of 18.94 ± 0.066 (F2) to 20.08 ± 0.07 mg per unit film (F1). The films exhibited controlled release ranging from 58.76 ± 1.62 to 91.45 ± 1.02 % over a period > 6 h. The films containing 20 mg diltiazem hydrochloride, polyvinyl alcohol (10 %) and polyvinyl pyrrolidone (1 % w/v) i.e. formulation F5, showed moderate swelling, convenientresidence time and promising drug release, and thus can be selected for further development of a buccal film for potential therapeutic uses.Conclusion: The developed formulation is a potential bioadhesive buccal system for delivering diltiazem directly to systemic circulation, circumventing first-pass metabolism, avoiding gastric discomfort and improving bioavailability at a minimal dose.Keywords: Bioadhesive, Cardiac, Diltiazem, Calcium channel blocker, Buccal film, Bioavailability, Sodium carboxymethylcellulose, Polyvinyl pyrrolidone, Polyvinyl alcoho
Two-component polariton condensate in optical microcavity
We present a scheme for engineering the extended two-component Bose-Hubbard
model using polariton condensate supported by optical microcavity. Compared to
the usual two-component Bose-Hubbard model with only Kerr nonlinearity, our
model includes a nonlinear tunneling term which depends on the number
difference of the particle in the two modes. In the mean field treatment, this
model is an analog to a nonrigid pendulum with a variable pendulum length whose
sign can be also changed. We study the dynamic and ground state properties of
this model and show that there exists a first-order phase transition as the
strength of the nonlinear tunneling rate is varied. Furthermore, we propose a
scheme to obtain the polariton condensate wave function.Comment: 9 pages, 8 figure
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