Lepton Flavor Violating Decays of Neutral Higgses in Extended Mirror Fermion Model

We perform the one-loop induced charged lepton flavor violating decays of the neutral Higgses in an extended mirror fermion model with non-sterile electroweak-scale right-handed neutrinos and a horizontal $A_4$ symmetry in the lepton sector. We demonstrate that for the 125 GeV scalar $h$ there is tension between the recent LHC result ${\cal B}(h \to \tau \mu) \sim$ 1% and the stringent limits on the rare processes $\mu \to e \gamma$ and $\tau \to (\mu$ or $e) \gamma$ from low energy experiments.Comment: 23 pages, 3 figures. Added some of referenc

Value Creation in E-Business: The Case Study of Trend Micro

In this paper, we examine the impact of actor-network field on value creation by integrating the concepts of actor-network and organizational field. In electronic business and commerce, researchers have emphasized the various sources of value creation, yet little attention has been paid to examine the issue from a cognitive or “field” perspective. Using Trend Micro as a case study, the paper demonstrates how a firm can construct a field in the community of Internet to create value and profits. Our approach and analysis are dynamic, rather than static. We show how Trend Micro is able to drive its associated actors, customers and business members to develop an evolutionary, dynamic actor-network field that serves to decrease uncertainty and increase trust. This, in turn, creates a lock-in effect and thus leads to enormous value creation

Torsion of right middle lobe after a right upper lobectomy

Lobar torsion after lung resection is a quite rare complication. A 50-year-old woman presented typical features on chest radiographs and CT(computed tomography) scan of lobar torsion after a right upper lobectomy. After emergency lobectomy of right middle lobe, the patient recovered well and discharged 10 days after the second operation

Use of Fomepizole in Pediatric Methanol Exposure: The First Case Report in Taiwan and a Literature Review

Methanol poisoning is rare in the pediatric population, but a delay in diagnosis and intervention may cause severe morbidity and mortality. The current therapy for methanol poisoning is ethanol or fomepizole, which acts as a competitive inhibitor of hepatic alcohol dehydrogenase to inhibit the production of toxic metabolites derived from the oxidation of methanol. However, clinical experience in pediatric methanol poisoning is limited, and the safety profiles of the antidotes have not been established in children, especially in Asian populations. This is the first case to describe the use of fomepizole in a child with methanol exposure in Taiwan

Electronic and structural fingerprints of charge density wave excitations in extreme ultraviolet transient absorption spectroscopy

Femtosecond core-level transient absorption spectroscopy is utilized to investigate photoinduced dynamics of the charge density wave in 1T-TiSe2 at the Ti M2,3 edge (30-50 eV). Photoexcited carriers and phonons are found to primarily induce spectral red-shifts of core-level excitations, and a carrier relaxation time and phonon heating time of approximately 360 fs and 1.0 ps are extracted, respectively. Pronounced oscillations in delay-dependent absorption spectra are assigned to coherent excitations of the optical $A_{1g}$ phonon (6.0 THz) and the $A_{1g}^*$ charge density wave amplitude mode (3.3 THz). By comparing the measured spectra with time-dependent density functional theory simulations, we determine the directions of the momentary atomic displacements of both coherent modes and estimate their amplitudes. This work presents a first look on charge density wave excitations with table-top core-level transient absorption spectroscopy, enabling simultaneous access to electronic and lattice excitation and relaxation

Resveratrol retards progression of diabetic nephropathy through modulations of oxidative stress, proinflammatory cytokines, and AMP-activated protein kinase

<p>Abstract</p> <p>Background</p> <p>Diabetic nephropathy (DN) has been recognized as the leading cause of end-stage renal disease. Resveratrol (RSV), a polyphenolic compound, has been indicated to possess an insulin-like property in diabetes. In the present study, we aimed to investigate the renoprotective effects of RSV and delineate its underlying mechanism in early-stage DN.</p> <p>Methods</p> <p>The protective effects of RSV on DN were evaluated in streptozotocin (STZ)-induced diabetic rats.</p> <p>Results</p> <p>The plasma glucose, creatinine, and blood urea nitrogen were significantly elevated in STZ-induced diabetic rats. RSV treatment markedly ameliorated hyperglycemia and renal dysfunction in STZ-induced diabetic rats. The diabetes-induced superoxide anion and protein carbonyl levels were also significantly attenuated in RSV-treated diabetic kidney. The AMPK protein phosphorylation and expression levels were remarkably reduced in diabetic renal tissues. In contrast, RSV treatment significantly rescued the AMPK protein expression and phosphorylation compared to non-treated diabetic group. Additionally, hyperglycemia markedly enhanced renal production of proinflammatory cytokine IL-1β. RSV reduced IL-1β but increased TNF-α and IL-6 levels in the diabetic kidneys.</p> <p>Conclusions</p> <p>Our findings suggest that RSV protects against oxidative stress, exhibits concurrent proinflammation and anti-inflammation, and up-regulates AMPK expression and activation, which may contribute to its beneficial effects on the early stage of DN.</p