1,214 research outputs found

    Ward Identities and High-energy Scattering Amplitudes in String Theory

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    High-energy limit of stringy Ward identities derived from the decoupling of two types of zero-norm states in the old covariant first quantized (OCFQ) spectrum of open bosonic string are used to check the consistency of saddle point calculations of high energy scattering amplitudes of Gross and Mende and Gross and Manes. Some inconsistencies of their saddle point calculations are found even for the string-tree scattering amplitudes of the excited string states. We discuss and calculate the missing terms of the calculation by those authors to recover the stringy Ward identities. In addition, based on the tree-level stringy Ward identities, we give the proof of a general formula, which was proposed previously, of all high energy four-point string-tree amplitudes of arbitrary particles in the string spectrum. In this formula all such scattering amplitudes are expressed in terms of those of tachyons as conjectured by Gross. The formula is extremely simple which manifestly demonstrates the universal high energy behavior of the interactions among all string states.Comment: 1 typo, to appear in Nucl. Phys.

    Zero-norm states and stringy symmetries

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    We identify spacetime symmetry charges of 26D open bosonic string theory from an infinite number of zero-norm states (ZNS) with arbitrary high spin in the old covariant first quantized string spectrum. We give various evidences to support this identification. These include massive sigma-model calculation, Witten string field theory calculation, 2D string theory calculation and, most importantly, three methods of high-energy stringy scattering amplitude calculations. The last calculations explicitly prove Gross's conjectures in 1988 on high energy symmetry of string theory.Comment: 6 pages. Talks presented by Jen-Chi Lee at XXVIII Spanish Relativity Meeting (ERE2005),"A Century of Relativity Physics",Oviedo,Spain,6-10 Sep 2005 and "4th Meeting on constrained Dynamics and Quantum Gravity",Cala Gonone,Sardinia,Italy,12-16 Sep 2005. To appear in the Journal of Physics: Conference Serie

    Web-based vocational English: development, practice and problems

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    In response to the IT in education initiative by Hong Kong\u27s Vocational Training Council, a project on web-based vocational English course was carried out at the Language Centre of Hong Kong Institute of Vocational Education (Tsing Yi) in September 1999. This project aimed to find out how to enhance language learning through integrating web-based and classroom-based activities. A survey was administered to investigate students\u27 response to this type of learning experience. In this paper, the development of the web-based activities and the integration process would be described and the survey results would be discussed

    Inhibitory Effects of Resveratrol on PDGF-BB-Induced Retinal Pigment Epithelial Cell Migration via PDGFRβ, PI3K/Akt and MAPK Pathways

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    Purpose: In diseases such as proliferative vitreoretinopathy (PVR), proliferative diabetic retinopathy, and age-related macular degeneration, retinal pigment epithelial (RPE) cells proliferate and migrate. Moreover, platelet-derived growth factor (PDGF) has been shown to enhance proliferation and migration of RPE cells in PVR. Even resveratrol can suppress the migration and adhesion of many cell types, its effects on RPE cell migration and adhesion remain unknown. In this study, we investigated the inhibitory effects of resveratrol on RPE cell migration induced by PDGF-BB, an isoform of PDGF, and adhesion to fibronectin, a major ECM component of PVR tissue. Methods: The migration of RPE cells was assessed by an electric cell-substrate impedance sensing migration assay and a Transwell migration assay. A cell viability assay was used to determine the viability of resveratrol treated-cells. The cell adhesion to fibronectin was examined by an adhesion assay. The interactions of resveratrol with PDGF-BB were analyzed by a dot binding assay. The PDGF-BB-induced signaling pathways were determined by western blotting and scratch wound healing assay. Results: Resveratrol inhibited PDGF-BB-induced RPE cell migration in a dose-dependent manner, but showed no effects on ARPE19 cell adhesion to fibronectin. The cell viability assay showed no cytotoxicity of resveratrol on RPE cells and the dot binding assay revealed no direct interactions of resveratrol with PDGF-BB. Inhibitory effects of resveratrol on PDGF-BB-induced platelet-derived growth factor receptor β (PDGFRβ) and tyrosine phosphorylation and the underlying pathways of PI3K/Akt, ERK and p38 activation were found; however, resveratrol and PDGF-BB showed no effects on PDGFRα and JNK activation. Scratch wound healing assay demonstrated resveratrol and the specific inhibitors of PDGFR, PI3K, MEK or p38 suppressed PDGF-BB-induced cell migration. Conclusions: These results indicate that resveratrol is an effective inhibitor of PDGF-BB-induced RPE cell migration via PDGFRβ, PI3K/Akt and MAPK pathways, but has no effects on the RPE cell adhesion to fibronectin

    Accretion-induced Collapse of Dark Matter-admixed Rotating White Dwarfs: Dynamics and Gravitational-wave Signals

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    We present two-dimensional hydrodynamic simulations of the accretion-induced collapse (AIC) of rotating white dwarfs admixed with an extended component of dark matter (DM) comprising of sub-GeV degenerate fermionic DM particles. We find that the DM component would follow the collapse of the normal matter (NM) component to become a bound DM core. Thus, we demonstrate how a DM-admixed neutron star could form through DM-admixed AIC (DMAIC) for the first time, with the dynamics of DM taken into account. The gravitational-wave (GW) signature from the DMAIC shows distinctive features. In the diffusive DM limit, the DM admixture indirectly suppresses the post-bounce spectral peak of the NM GWs. In the compact DM limit, the collapse dynamics of the DM in a Milky Way event generate GWs that are strong enough to be detectable by Advanced LIGO as continuous low-frequency (<1000< 1000 Hz) signals after the NM core bounce. Our study not only is the first-ever computation of GW from a collapsing DM object but also provides the key features to identify DM in AIC events through future GW detections.Comment: 14 pages, 13 figure

    Surface Analysis of Graphene and Graphite

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    Graphene and graphite are two widely studied carbon materials. Due to their particular properties and structure, graphene and graphite have been used in a variety of fields such as electronic devices and sensors. The surface properties of graphene and graphite as well as their derivatives are strongly connected to the performances of devices and sensors. Thus, it is necessary to choose appropriate surface analysis techniques for characterization, which are not only useful in the understanding of the surface composition and structure but also in the design and development of these types of materials. X-ray photoelectron spectroscopy (XPS) and time-of-flight secondary ion mass spectrometry (ToF-SIMS) have been two of the key surface analysis techniques that are widely used to characterize these surfaces. In this chapter, an overview of the applications of XPS and ToF-SIMS in the study of the surfaces of graphene and graphite is present. We hope that the information provided will simulate more exciting and inspiring research on graphene and graphite and promote practical applications of these carbon materials in the future

    High-energy zero-norm states and symmetries of string theory

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    High-energy limit of zero-norm states (HZNS) in the old covariant first quantized (OCFQ) spectrum of the 26D open bosonic string, together with the assumption of a smooth behavior of string theory in this limit, are used to derive infinitely many linear relations among the leading high-energy, fixed angle behavior of four point functions of different string states. As a result, ratios among all high-energy scattering amplitudes of four arbitrary string states can be calculated algebraically and the leading order amplitudes can be expressed in terms of that of four tachyons as conjectured by Gross in 1988. A dual calculation can also be performed and equivalent results are obtained by taking the high-energy limit of Virasoro constraints. Finally, as a consistent sample calculation, we compute all high-energy scattering amplitudes of three tachyons and one massive state at the leading order by saddle-point approximation to justify our results.Comment: 10 pages, no figure, modifications of text and reference

    Crystallization of Adenylylsulfate Reductase from Desulfovibrio gigas: A Strategy Based on Controlled Protein Oligomerization

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    Adenylylsulfate reductase (adenosine 5′-phosphosulfate reductase, APS reductase or APSR, E.C.1.8.99.2) catalyzes the conversion of APS to sulfite in dissimilatory sulfate reduction. APSR was isolated and purified directly from massive anaerobically grown Desulfovibrio gigas, a strict anaerobe, for structure and function investigation. Oligomerization of APSR to form dimers–α_2β_2, tetramers–α_4β_4, hexamers–α_6β_6, and larger oligomers was observed during purification of the protein. Dynamic light scattering and ultracentrifugation revealed that the addition of adenosine monophosphate (AMP) or adenosine 5′-phosphosulfate (APS) disrupts the oligomerization, indicating that AMP or APS binding to the APSR dissociates the inactive hexamers into functional dimers. Treatment of APSR with β-mercaptoethanol decreased the enzyme size from a hexamer to a dimer, probably by disrupting the disulfide Cys156—Cys162 toward the C-terminus of the β-subunit. Alignment of the APSR sequences from D. gigas and A. fulgidus revealed the largest differences in this region of the β-subunit, with the D. gigas APSR containing 16 additional amino acids with the Cys156—Cys162 disulfide. Studies in a pH gradient showed that the diameter of the APSR decreased progressively with acidic pH. To crystallize the APSR for structure determination, we optimized conditions to generate a homogeneous and stable form of APSR by combining dynamic light scattering, ultracentrifugation, and electron paramagnetic resonance methods to analyze the various oligomeric states of the enzyme in varied environments
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