Epidémiologie et prise en charge de l’insuffisance cardiaque dans un centre marocain

Il s'agit d'une étude observationnelle prospective colligée dans le service des soins intensifs et rythmologie de l'Hôpital militaire d'instruction Mohammed V de Rabat, entre décembre 2008 et décembre 2014, portant sur 424 patients hospitalisés pour insuffisance cardiaque. L'âge moyen était de 60,91±12,77 Les principaux facteurs de risque cardiovasculaires rencontrés étaient : l'hypertension artérielle (46%), le tabagisme (45%), et le diabète (43%). Cliniquement, 63% des patients ont été admis pour insuffisance cardiaque gauche. Le ventricule gauche était dilaté dans 58% des cas, avec une fraction d'éjection moyenne estimée à 36,33±13,5%. L'étiologie dominante était la cardiopathie ischémique (254 cas). En plus d'un traitement médical optimal, 14.4% de nos patients ont fait l'objet d'une resynchronisation cardiaque avec ou sans système de défibrillation. L'évolution intra-hospitalière sous traitement médical était marquée par 26 décès.la durée moyenne d'hospitalisation était de 12,1±6,6 jours.Pan African Medical Journal 2016; 2

0422: Atrial fibrillation (AF): the cardioversion in the era of ablation

IntroductionIf the management of atrial fibrillation in its thromboembolic component knows more adherences to recommendations, it should be noted that the rhythmic component is experiencing a trend towards acceptance of the AF at the expense of a restoration strategy sinus rhythm.PurposeTo evaluate the effectiveness of the drug cardioversion or electrical cardioversion in patients hospitalized in the cardiology department of HMIMV Rabat.Materials and MethodsThis is a prospective study conducted over a period of one year, including 45 patients with non-valvular AF, candidates for chemical or electrical cardioversion. All our patients have undergone transthoracic echocardiography, sometimes supplemented with a transesophageal echocardiography and an assessment of thyroidResultsThe average age of our patients was 52.7 years with a sex ratio 2/1. 25% of our patients had hypertensive heart disease, 8% ischemic heart disease, 4% dilated cardiomyopathy and the rest had a healthy heart. The average diameter of the left atrium was 41cm with an average surface to 19cm2. 60% of our patients have undergone cardioversion by external shock, and 40% of theme by injection of amiodarone or flecainide. The rate of restoration of sinus rhythm was 78%, with a recurrence rate at one month 19%. The predictive factors of recurrence were an ancient atrial fibrillation, a large left atrium and a score CHA2DS2-VASC ≥ 1.ConclusionThis study, showing an acceptable level of restoration and maintenance of sinus rhythm, confirms the interest of promoting a strategy of rhythm control, subject to patient selection on predictors of success

093 Look on the hold of heart failure management in Morocco, about 294 patient

Objectivethe objective was to identify the epidemiological, clinical and the outcome of heart failure (HF) in a Moroccan hospital.MethodA retrospective study using a serie of 294 patients hospitalized in our service from January 2005 to December 2008.ResultsThe HF occupies 14% of hospitalizations. The mean length of stay was 14±3.1 days. The mean age was 58±11.5 years. Men were mostly represented with a ratio H / F=3.5. The main cardiovascular risk factor was smoking (55%) followed by hypertension (40%) and diabetes (35%). Dyspnea was the main symptom reported in 91% of the cases. The clinical presentation was that of left (65%), right (22%) and global(23%) HF. Among electric signs, we found Atrial fibrillation (30%), a Q-wave (58%) and left ventricular hypertrophy (28%). the chest x-ray showed a cardiomegaly (89%) and signs of pulmonary overload (86%). Biology showed electrolyte abnormalities in half of the cases, renal failure (35%) and anemia (28%). In echocardiography, the mean left ventricular ejection fraction (LVEF) was 34.5±5.4%. LVEF was > 45% for 26% of patients. 134 patients underwent a coronary angiography which objectified coronary damage in 84% of the cases. The main causes were ischemic heart disease (42%), valvular heart disease(24%) and hypertension (13%). most used drugs were angiotensin converting enzym inhibitors and diuretics. 21% of patients underwent a mitral valve replacement with mechanical prosthesis. Among patients with coronary artery disease, 33% were revascularized by coronary bypass (21%) and coronary angioplasty (12%). Cardiac resynchronization was performed for 19 patients using implantable automatic defibrillator for 3 of them.Hospital mortality was 10%.ConclusionThe main features of this population is the relatively young age, male predominance, ischemic heart disease as a leading cause and low rate of HF with preserved systolic function

Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes

Online Correction for: https://doi.org/10.1038/s41586-020-2493-4 | Erratum for https://bura.brunel.ac.uk/handle/2438/21299In the version of this article initially published, two members of the ENCODE Project Consortium were missing from the author list. Rizi Ai (Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA, USA) and Shantao Li (Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA) are now included in the author list. These errors have been corrected in the online version of the article : 'Expanded encyclopaedias of DNA elements in the human and mouse genomes'.https://www.nature.com/articles/s41586-021-04226-3https://www.nature.com/articles/s41586-021-04226-

2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death the Task Force for the Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death of the European Society of Cardiology (ESC) Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC)

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