INDENTATION COEFFICIENT AND INDENTATION BEHAVIOR OF BAMBOO

Bamboo hardness test standards are not available. The study aimed to develop a new method of testing bamboo indentation hardness. With the V-shaped prismatic head, bamboo rings with different lengths were tested. The V-shaped indentation coefficient (IC) was defined. The results showed that the IC had a good correlation with compression strength. The V-shaped IC increased with the increase in the longitudinal height of the bamboo pole, and the variance analysis showed significant differences in different axial directions of the same bamboo ring. In addition, the correlation between density and IC is good. The V-shaped IC can be applied in bamboo gr

MFR-Net: Multi-faceted Responsive Listening Head Generation via Denoising Diffusion Model

Face-to-face communication is a common scenario including roles of speakers and listeners. Most existing research methods focus on producing speaker videos, while the generation of listener heads remains largely overlooked. Responsive listening head generation is an important task that aims to model face-to-face communication scenarios by generating a listener head video given a speaker video and a listener head image. An ideal generated responsive listening video should respond to the speaker with attitude or viewpoint expressing while maintaining diversity in interaction patterns and accuracy in listener identity information. To achieve this goal, we propose the \textbf{M}ulti-\textbf{F}aceted \textbf{R}esponsive Listening Head Generation Network (MFR-Net). Specifically, MFR-Net employs the probabilistic denoising diffusion model to predict diverse head pose and expression features. In order to perform multi-faceted response to the speaker video, while maintaining accurate listener identity preservation, we design the Feature Aggregation Module to boost listener identity features and fuse them with other speaker-related features. Finally, a renderer finetuned with identity consistency loss produces the final listening head videos. Our extensive experiments demonstrate that MFR-Net not only achieves multi-faceted responses in diversity and speaker identity information but also in attitude and viewpoint expression.Comment: Accepted by ACM MM 202

OSM-Net: One-to-Many One-shot Talking Head Generation with Spontaneous Head Motions

One-shot talking head generation has no explicit head movement reference, thus it is difficult to generate talking heads with head motions. Some existing works only edit the mouth area and generate still talking heads, leading to unreal talking head performance. Other works construct one-to-one mapping between audio signal and head motion sequences, introducing ambiguity correspondences into the mapping since people can behave differently in head motions when speaking the same content. This unreasonable mapping form fails to model the diversity and produces either nearly static or even exaggerated head motions, which are unnatural and strange. Therefore, the one-shot talking head generation task is actually a one-to-many ill-posed problem and people present diverse head motions when speaking. Based on the above observation, we propose OSM-Net, a \textit{one-to-many} one-shot talking head generation network with natural head motions. OSM-Net constructs a motion space that contains rich and various clip-level head motion features. Each basis of the space represents a feature of meaningful head motion in a clip rather than just a frame, thus providing more coherent and natural motion changes in talking heads. The driving audio is mapped into the motion space, around which various motion features can be sampled within a reasonable range to achieve the one-to-many mapping. Besides, the landmark constraint and time window feature input improve the accurate expression feature extraction and video generation. Extensive experiments show that OSM-Net generates more natural realistic head motions under reasonable one-to-many mapping paradigm compared with other methods.Comment: Paper Under Revie

OPT: One-shot Pose-Controllable Talking Head Generation

One-shot talking head generation produces lip-sync talking heads based on arbitrary audio and one source face. To guarantee the naturalness and realness, recent methods propose to achieve free pose control instead of simply editing mouth areas. However, existing methods do not preserve accurate identity of source face when generating head motions. To solve the identity mismatch problem and achieve high-quality free pose control, we present One-shot Pose-controllable Talking head generation network (OPT). Specifically, the Audio Feature Disentanglement Module separates content features from audios, eliminating the influence of speaker-specific information contained in arbitrary driving audios. Later, the mouth expression feature is extracted from the content feature and source face, during which the landmark loss is designed to enhance the accuracy of facial structure and identity preserving quality. Finally, to achieve free pose control, controllable head pose features from reference videos are fed into the Video Generator along with the expression feature and source face to generate new talking heads. Extensive quantitative and qualitative experimental results verify that OPT generates high-quality pose-controllable talking heads with no identity mismatch problem, outperforming previous SOTA methods.Comment: Accepted by ICASSP202

FONT: Flow-guided One-shot Talking Head Generation with Natural Head Motions

One-shot talking head generation has received growing attention in recent years, with various creative and practical applications. An ideal natural and vivid generated talking head video should contain natural head pose changes. However, it is challenging to map head pose sequences from driving audio since there exists a natural gap between audio-visual modalities. In this work, we propose a Flow-guided One-shot model that achieves NaTural head motions(FONT) over generated talking heads. Specifically, the head pose prediction module is designed to generate head pose sequences from the source face and driving audio. We add the random sampling operation and the structural similarity constraint to model the diversity in the one-to-many mapping between audio-visual modality, thus predicting natural head poses. Then we develop a keypoint predictor that produces unsupervised keypoints from the source face, driving audio and pose sequences to describe the facial structure information. Finally, a flow-guided occlusion-aware generator is employed to produce photo-realistic talking head videos from the estimated keypoints and source face. Extensive experimental results prove that FONT generates talking heads with natural head poses and synchronized mouth shapes, outperforming other compared methods.Comment: Accepted by ICME202

Effect of Kang Fu Yan capsule on phenol mucilage-induced intrauterine adhesion injury in female rats

Purpose: To investigate the effect of Kang fu yan capsule (KFYC) on phenol mucilage-induced intrauterine adhesion (IUA) in a rat model, and the underlying mechanisms. Methods: An IUA model was established by injecting 0.06 mL of 25 % phenol mucilage into the uterus of female Sprague-Dawley rats. The IUA model rats (n=59) were randomly divided into 5 groups: IUA group, fuke qianjin tablet group (FKQJT, 0.22 mg/kg), and 3 KFYC groups given different doses of the drug i.e. 0.13, 0.39and 1.17 mg/kg. A group of 10 healthy female rats served as control. After 19 days treatment, blood samples were collected for determination of IL-2 and IL-10 by ELISA, while uterine tissues were subjected to histological examination using hematoxylin and eosin staining (H&E) and Masson staining. Expressions of Notch1, recombination signal binding protein-JK (RBP-JK), a disintegrin and metalloprotease (ADAM)-12, ADAM-15, matrix metalloprotein-9 (MMP-9), and inhibitor of NF-κB (IĸB) in uterine tissues were determined using RT-qPCR and western blot analysis. Results: Compared to IUA group, histological results showed reduced inflammatory cell infiltration in rat uterine tissue of KFYC group. Moreover, KFYC significantly reversed uterine fibrosis (p < 0.05). Serum concentrations of IL-2 significantly decreased in KFYC groups (p < 0.05 or p < 0.01), and there was significant increases the serum concentrations of IL-10 in KFYC groups (p < 0.05 or < 0.01), when compared to IUA group. The mRNA and protein expressions of Notch1, RBP-JK, ADAM-12, ADAM-15, MMP-9 were also significantly down-regulated (p < 0.05), while protein expression of IĸB was upregulated in KFYC group, when compared to IUA group. Conclusion: KFYC exerts an anti-IUA effect via amelioration of uterine inflammation and fibrosis, probably via a mechanism involving regulation of Notch1/ADAM pathway

Gut microbiome, T cell subsets, and cytokine analysis identify differential biomarkers in tuberculosis

IntroductionThe gut microbiota, T cell subsets, and cytokines participate in tuberculosis (TB) pathogenesis. To date, the mechanisms by which these factors interactively promote TB development at different time points remain largely unclear. In the context of this study, We looked into the microorganisms in the digestive tract, T cell types, and cytokines related to tuberculosis.MethodsAccording to QIIME2, we analyzed 16SrDNA sequencing of the gut microbiome on the Illumina MiSeq. Enzyme-linked immunosorbent assay was used to measure the concentrations of cytokines.ResultsWe showed the presence of 26 identifiable differential microbiomes in the gut and 44 metabolic pathways between healthy controls and the different time points in the development of TB in patients. Five bacterial genera (Bacteroides, Bifidobacterium, Faecalibacterium, Collinsella, and Clostridium) were most closely associated with CD4/CD8, whereas three bacterial taxa (Faecalibacterium, Collinsella, and Clostridium) were most closely associated with CD4. Three bacterial taxa (Faecalibacterium, Ruminococcus, and Dorea) were most closely associated with IL-4. Ruminococcus was most closely associated with IL-2 and IL-10.ConclusionDiverse microorganisms, subsets of T cells, and cytokines, exhibiting varying relative abundances and structural compositions, were observed in both healthy controls and patients throughout distinct phases of tuberculosis. Gaining insight into the function of the gut microbiome, T cell subsets, and cytokines may help modulate therapeutic strategies for TB

DIFFERENT EXPLORATION ACTIVITY AND DETECTION THRESHOLD TOWARDS ODOR SETS BETWEEN CONNEXIN 36 KNOCKOUT MICE AND WILD-TYPE MICE

The sense of smell allows an organism to be aware of the chemical information of the external world. In most land animals, the olfactory system enables the perception of both volatile chemicals, as well as pheromones--chemicals released by animals that regulate their social activities. Among several factors that mediate olfaction, connexin 36 (Cx36), a subunit of gap junctions, has been suggested to play a crucial role in the olfactory system. In the research presented herein, I performed habituation/dishabituation studies on both Cx36 knockout (Cx36 KO) and wild-type mice to determine their exploration patterns towards four odorants. The results indicate that Cx36 KO and wild-type mice behaved differently when they were given defined odorants. In general, Cx36 KO mice spent more time exploring odorants. Cx36 KO and wild-type mice also exhibited different detection threshold towards given odorants. Moreover, cross-habituation between benzaldehyde and octaldehyde was established in Cx36 KO mice at the concentration of 10-4%, which was different from that in wild-type mice. These results may suggest important functions of Cx36 gap junctions in odor detection and integration in mammals. Keywords: Connexin 36, gap junction, olfactory system, habituation/dishabituationM.S. in Biology, May 201

An Experimental Study on Strengthening Recycled Aggregates Considering Dry Mixing before Slurry Coating

The strengthening of recycled aggregates is a critical issue, as the low strength of recycled aggregates is the main reason that limits their widespread use. The slurry coating method can strengthen the recycled aggregates by repairing the aggregate surface, but it is hard to improve the internal strength due to the existence of pores and cracks. In this study, a new methodology considering dry mixing with fines to fill and bond the internal pores and cracks before slurry coating is proposed. Twelve strengthened samples considering different combinations of dry-mixing fines and coating solutions were prepared, and the basic physical and mechanical properties were compared, including the water-absorption rate, crushing value, and apparent density with unstrengthened aggregates. The results indicate that the proposed methodology can change the water-absorption rate significantly and improve the crushing resistance and apparent density of the recycled aggregates. A high correlation between the apparent density and the crushing value was also observed. Furthermore, the strengthening mechanism of dry mixing was also investigated by scanning electron microscopy. The micromorphology of the strengthened aggregates indicates that internal pores and cracks can be filled by dry mixing fines and then bonded together after hydration