624 research outputs found
The ultracool dwarf DENIS-P J104814.7-395606. Chromospheres and coronae at the low-mass end of the main-sequence
We have obtained an XMM-Newton observation and a broad-band spectrum from the
ultraviolet to the near infrared with X-Shooter for one of the nearest M9
dwarfs, DENIS-P J1048-3956 (4pc). We integrate these data by a compilation of
activity parameters for ultracool dwarfs from the literature with the aim to
advance our understanding of these objects by comparing them to early-M type
dwarf stars and the Sun.
Our deep XMM-Newton observation has led to the first X-ray detection of
DENIS-P J1048-3956 (log Lx = 25.1) as well as the first measurement of its V
band brightness (V = 17.35mag). Flux-flux relations between X-ray and
chromospheric activity indicators are here for the first time extended into the
regime of the ultracool dwarfs. The approximate agreement of DENIS-P J1048-3956
and other ultracool dwarfs with flux-flux relations for early-M dwarfs suggests
that the same heating mechanisms work in the atmospheres of ultracool dwarfs,
albeit weaker as judged from their lower fluxes. The observed Balmer decrements
of DENIS-P J1048-3956 are compatible with optically thick plasma in LTE at low,
nearly photospheric temperature or optically thin LTE plasma at 20000K.
Describing the decrements with CaseB recombination requires different emitting
regions for Halpha and the higher Balmer lines. The high observed Halpha/Hbeta
flux ratio is also poorly fitted by the optically thin models. We derive a
similarly high value for the Halpha/Hbeta ratio of vB10 and LHS2065 and
conclude that this may be a characteristic of ultracool dwarfs. We add DENIS-P
J1048-3956 to the list of ultracool dwarfs detected in both the radio and the
X-ray band. The Benz-Guedel relation between radio and X-ray luminosity of
late-type stars is well-known to be violated by ultracool dwarfs. We speculate
on the presence of two types of ultracool dwarfs with distinct radio and X-ray
behavior.Comment: accepted for publication in Astronomy & Astrophysic
Assessing Code Authorship: The Case of the Linux Kernel
Code authorship is a key information in large-scale open source systems.
Among others, it allows maintainers to assess division of work and identify key
collaborators. Interestingly, open-source communities lack guidelines on how to
manage authorship. This could be mitigated by setting to build an empirical
body of knowledge on how authorship-related measures evolve in successful
open-source communities. Towards that direction, we perform a case study on the
Linux kernel. Our results show that: (a) only a small portion of developers (26
%) makes significant contributions to the code base; (b) the distribution of
the number of files per author is highly skewed --- a small group of top
authors (3 %) is responsible for hundreds of files, while most authors (75 %)
are responsible for at most 11 files; (c) most authors (62 %) have a specialist
profile; (d) authors with a high number of co-authorship connections tend to
collaborate with others with less connections.Comment: Accepted at 13th International Conference on Open Source Systems
(OSS). 12 page
Bioengineered constructs combined with exercise enhance stem cell-mediated treatment of volumetric muscle loss
Valproic acid inhibits interferon-γ production by NK cells and increases susceptibility to <i>Listeria monocytogenes</i> infection
Electronic health records and patient registries in medical oncology departments in Spain
We aimed to evaluate the current situation of electronic health records (EHRs) and patient registries in the oncology departments of hospitals in Spain. This was a cross-sectional study conducted from December 2018 to September 2019. The survey was designed ad hoc by the Outcomes Evaluation and Clinical Practice Section of the Spanish Society of Medical Oncology (SEOM) and was distributed to all head of medical oncology department members of SEOM. We invited 148 heads of oncology departments, and 81 (54.7%) questionnaires were completed, with representation from all 17 Spanish autonomous communities. Seventy-seven (95%) of the respondents had EHRs implemented at their hospitals; of them, over 80% considered EHRs to have a positive impact on work organization and clinical practice, and 73% considered that EHRs improve the quality of patient care. In contrast, 27 (35.1%) of these respondents felt that EHRs worsened the physician-patient relationship and conveyed an additional workload (n = 29; 37.6%). Several drawbacks in the implementation of EHRs were identified, including the limited inclusion of information on both outpatients and inpatients, information recorded in free text data fields, and the availability of specific informed consent. Forty-six (56.7%) respondents had patient registries where they recorded information from all patients seen in the department. Our study indicates that EHRs are almost universally implemented in the hospitals surveyed and are considered to have a positive impact on work organization and clinical practice. However, EHRs currently have several drawbacks that limit their use for investigational purposes. Not applicable The online version contains supplementary material available at 10.1007/s12094-021-02614-9
The nearest young moving groups
The latest results in the research of forming planetary systems have led
several authors to compile a sample of candidates for searching for planets in
the vicinity of the sun. Young stellar associations are indeed excellent
laboratories for this study, but some of them are not close enough to allow the
detection of planets through adaptive optics techniques. However, the existence
of very close young moving groups can solve this problem. Here we have compiled
the members of the nearest young moving groups, as well as a list of new
candidates from our catalogue of late-type stars possible members of young
stellar kinematic groups, studying their membership through spectroscopic and
photometric criteria.Comment: Latex file with 16 pages, 4 figures. Available at
http://www.ucm.es/info/Astrof/invest/actividad/skg/skg_sag.html Accepted for
publication in: The Astrophysical Journal (ApJ
Grain Boundaries in Graphene on SiC(000) Substrate
Grain boundaries in epitaxial graphene on the SiC(000) substrate are
studied using scanning tunneling microscopy and spectroscopy. All investigated
small-angle grain boundaries show pronounced out-of-plane buckling induced by
the strain fields of constituent dislocations. The ensemble of observations
allows to determine the critical misorientation angle of buckling transition
. Periodic structures are found among the flat
large-angle grain boundaries. In particular, the observed highly ordered grain boundary is assigned to the previously
proposed lowest formation energy structural motif composed of a continuous
chain of edge-sharing alternating pentagons and heptagons. This periodic grain
boundary defect is predicted to exhibit strong valley filtering of charge
carriers thus promising the practical realization of all-electric valleytronic
devices
Bioengineered constructs combined with exercise enhance stem cell-mediated treatment of volumetric muscle loss
Volumetric muscle loss (VML) is associated with loss of skeletal muscle function, and current treatments show limited efficacy. Here we show that bioconstructs suffused with genetically-labelled muscle stem cells (MuSCs) and other muscle resident cells (MRCs) are effective to treat VML injuries in mice. Imaging of bioconstructs implanted in damaged muscles indicates MuSCs survival and growth, and ex vivo analyses show force restoration of treated muscles. Histological analysis highlights myofibre formation, neovascularisation, but insufficient innervation. Both innervation and in vivo force production are enhanced when implantation of bioconstructs is followed by an exercise regimen. Significant improvements are also observed when bioconstructs are used to treat chronic VML injury models. Finally, we demonstrate that bioconstructs made with human MuSCs and MRCs can generate functional muscle tissue in our VML model. These data suggest that stem cell-based therapies aimed to engineer tissue in vivo may be effective to treat acute and chronic VML
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