Some Physical and Mechanical Properties of Daniellia Ogea Harms Green Timber Species

Throughout the antediluvian and up to date, humans keep understanding the nature of wood which has been used to meet some bunches of human’s demands such as in industry, in framing and in war. This paper presents some physical and mechanical properties of Daniellia ogea (Iya) green timber specie freshly felled from matured trees in forests around Ilorin Local Government, Kwara-State, Nigeria and cut into structural sizes within the Wood workshop of University of Ilorin premises according to BS EN 408: 2003. The moisture content and the density were the physical properties tested while the mechanical properties were the modulus of rupture and the local modulus of elasticity in bending strength, the apparent modulus of elasticity, the compressive strength perpendicular to grain then the compressive strength and tensile strength parallel to grain using the Universal Testing Machine of 300kN capacity of the food laboratory of the department of Agriculture of the University. Then the basic and grade stresses were determined and found to conform to the BS 5268 codes of practice. The results obtained post-tests for the moisture content and the density had respectively average values of 140.45% and 854.67 kg/m3. Keywords: Timber, Apparent modulus of elasticity, Stresses, Bending, Density, Moisture content

Chemotherapy-Induced Late Transgenerational Effects in Mice

To our knowledge, there is no report on long-term reproductive and developmental side effects in the offspring of mothers treated with a widely used chemotherapeutic drug such as doxorubicin (DXR), and neither is there information on transmission of any detrimental effects to several filial generations. Therefore, the purpose of the present paper was to examine the long-term effects of a single intraperitoneal injection of DXR on the reproductive and behavioral performance of adult female mice and their progeny. C57BL/6 female mice (generation zero; G0) were treated with either a single intraperitoneal injection of DXR (G0-DXR) or saline (G0-CON). Data were collected on multiple reproductive parameters and behavioral analysis for anxiety, despair and depression. In addition, the reproductive capacity and health of the subsequent six generations were evaluated. G0-DXR females developed despair-like behaviors; delivery complications; decreased primordial follicle pool; and early lost of reproductive capacity. Surprisingly, the DXR-induced effects in oocytes were transmitted transgenerationally; the most striking effects being observed in G4 and G6, constituting: increased rates of neonatal death; physical malformations; chromosomal abnormalities (particularly deletions on chromosome 10); and death of mothers due to delivery complications. None of these effects were seen in control females of the same generations. Long-term effects of DXR in female mice and their offspring can be attributed to genetic alterations or cell-killing events in oocytes or, presumably, to toxicosis in non-ovarian tissues. Results from the rodent model emphasize the need for retrospective and long-term prospective studies of survivors of cancer treatment and their offspring