28 research outputs found
Recours à des enregistrements vidéos de simulations d’échanges pharmacien-patient au sein d’une pharmacie didactique pour sensibiliser les étudiants à l’importance decette relation et les aider à réfléchir à des situations-problèmes
Expression and role of Placental Growth Factor (PLGF) in the inflammatory context resulting from nerve injury, the Wallerian Degeneration.
Role of Placental Growth Factor (PLGF) in the inflammatory context resulting from nerve injury, the Wallerian Degeneration
Le processus inflammatoire dans la dégénérescence Wallérienne: Rôle du Facteur de croissance placentaire (PLGF).
Placental growth factor: a tissue modelling factor with therapeutic potentials in neurology?
Placental growth factor (PlGF) is an angiogenic factor that belongs to the vascular endothelial growth factor (VEGF) family. Besides its well known capacity to potentiate the angiogenic action of VEGF, PlGF also participates in inflammatory processes by attracting and activating monocytes; it plays therefore more specifically a role in pathological conditions. PIGF and its two receptors, VEGFR-1 and neuropilins (NRPs), are expressed in the brain and increase after experimental stroke, but their precise functions in the nervous system remain underexplored. In this review article, we summarize present knowledge on the role of PlGF in various nervous system disease processes. Given the available data, P1GF has neuroprotective and neurotrophic properties that make it an actor of considerable interest in the pathophysiology and potentially in the therapy of degenerative and traumatic brain or spinal cord diseases