Métastases mammaires d’un adénocarcinome gastrique associées à une grossesse de 32 semaines d’aménorrhée: à propos d’un cas rare

Les métastases mammaires ne représentent que 0,4 à 2% des tumeurs malignes du sein. L’origine gastrique est exceptionnellement rapportée. Encore plus rare est l’association des métastases mammaires et ovariennes provenant de l’estomac. De par leur rareté et la non spécificité des signes cliniques et radiologiques, les métastases mammaires peuvent être confondues avec un cancer primitif et être à l’origine d’un traitement mutilant non approprié. Nous rapportons le cas d’un adénocarcinome gastrique métastatique au niveau mammaire et ovarien chez une patiente jeune de 32 ans et enceinte de 32 Semaines d’aménorrhée, qui est à notre connaissance le premier cas rapporté au cours de la grossesse. A travers notre cas, nous soulignons les caractéristiques épidémiologiques, diagnostiques, thérapeutiques et pronostiques de cette entité très rare, dont la connaissance est nécessaire afin d’éviter les erreurs diagnostic et les prise en charge non adaptée qui peut suivre.Key words: Métastase mammaire, cancer gastrique, diagnostic, grossess

Uterine Inversion; A case report

The puerperal uterine inversion is a rare and severe complication occurring in the third stage of labour. The mechanisms are not completely known. However, extrinsic factors such as oxytocic arrests after a prolonged labour, umbilical cord traction or abdominal expression are pointed. Other intrinsic factors such as primiparity, uterine hypotonia, various placental localizations, fundic myoma or short umbilical cord were also reported. The diagnosis of the uterine inversion is mainly supported by clinical symptoms. It is based on three elements: haemorrhage, shock and a strong pelvic pain. The immediate treatment of the uterine inversion is required. It is based on a medical reanimation associated with firstly a manual reduction then surgical treatment using various techniques. We report an observation of a 25 years old grand multiparous patient with a subacute uterine inversion after delivery at home

Endometrial Stromal Nodule: Report of a Case

Endometrial stromal nodule (ESN) is the least common of the endometrial stromal tumors. They are rare neoplasms which are diagnosed in most instances by light microscopy. Although such nodules are benign, hysterectomy has been considered the treatment of choice to determine the margins of the tumor required for diagnosis and to differentiate it from invasive stromal sarcoma Whose prognosis is totally different. We report a case of a 45 years old woman, with presurgical diagnosis of adnexal mass or uterine tumor. She underwent a total abdominal hysterectomy. Pathologic examination revealed an endometrial stromal nodule. Through this observation, we insist on the fact that the ESNs are rare and benign entities which must be differentiated from the other invasive malignant stromal tumors; this can change the final prognosis

Correspondance: A Rare Case of a Giant Pelvic Retroperitoneal Epidermoid Cyst

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Recurrence of Uterine Rupture in a Pseudo-Unicornuate Uterus at 17 Weeks of Amenorrhea: Case Report and Literature Review

Pregnancy in a rudimentary horn is a very rare condition. It is responsible for several complications. Prognosis is reserved because the natural evolution generally leads to a cataclysmic uterine rupture at the beginning of the second trimester. Classically, the treatment after foetal extraction consists of ablation of the rudimentary horn and associated fallopian tube. We report the obstetric outcome of a patient with history of rudimentary uterine horn rupture, the treatment of which was ablation of the rudimentary horn

Active regulatory T-cells contribute to broadened T-cell repertoire diversity in ivIg-treated SLE patients

Octapharma

Broadened T-cell Repertoire Diversity in ivIg-treated SLE Patients is Also Related to the Individual Status of Regulatory T-cells

Intravenous IgG (ivIg) is a therapeutic alternative for lupus erythematosus, the mechanism of which remains to be fully understood. Here we investigated whether ivIg affects two established sub-phenotypes of SLE, namely relative oligoclonality of circulating T-cells and reduced activity of CD4 + Foxp3+ regulatory T-cells (Tregs) reflected by lower CD25 surface density.Octapharma research funding; Fundação para a Ciência e a Tecnologia postdoctoral fellowships: (SFRH/BPD/20806/2004, SFRH/BPD/34648/2007); FCT Programa Pessoa travel grant