Central Europe Town Laboratories. Cities, memory and critical identities citizenship in international education.

In this article, we discuss the potential of cities and architectural environments as important spaces in conducting international education. Introducing La-Municipal boratoria of Central Europe, our proprietary methodological concept giving shape to the pedagogical activities we undertake in the context of education international, and more specifically as part of study programs abroad allows for American students staying at universities in Poland and Central Europe.We begin the description of this concept by considering the dimensions of the city that make it cities are currently playing a key role in international education as well as in practicalour pedagogy model. Then we explain in detail how it works they include Municipal Laboratories, citing specific examples taken from them from our work with student

Central Europe Town Laboratories. Cities, memory and critical identities citizenship in international education.

In this article, we discuss the potential of cities and architectural environments as important spaces in conducting international education. Introducing La-Municipal boratoria of Central Europe, our proprietary methodological concept giving shape to the pedagogical activities we undertake in the context of education international, and more specifically as part of study programs abroad allows for American students staying at universities in Poland and Central Europe.We begin the description of this concept by considering the dimensions of the city that make it cities are currently playing a key role in international education as well as in practicalour pedagogy model. Then we explain in detail how it works they include Municipal Laboratories, citing specific examples taken from them from our work with student

Local hyperthyroidism promotes pancreatic acinar cell proliferation during acute pancreatitis

Proliferation of pancreatic acinar cells is a critical process in the pathophysiology of pancreatic diseases, because limited or defective proliferation is associated with organ dysfunction and patient morbidity. In this context, elucidating the signalling pathways that trigger and sustain acinar proliferation is pivotal to develop therapeutic interventions promoting the regenerative process of the organ.In this study we used genetic and pharmacological approaches to manipulate both local and systemic levels of thyroid hormones to elucidate their role in acinar proliferation following caerulein‐mediated acute pancreatitis in mice. In addition, molecular mechanisms mediating the effects of thyroid hormones were identified by genetic and pharmacological inactivation of selected signalling pathways.In this study we demonstrated that levels of the thyroid hormone 3,3’,5‐triodo‐L‐thyronine (T3) transiently increased in the pancreas during acute pancreatitis. Moreover, by using genetic and pharmacological approaches to manipulate both local and systemic levels of thyroid hormones, we showed that T3 was required to promote proliferation of pancreatic acinar cells, without affecting the extent of tissue damage or inflammatory infiltration.Finally, upon genetic and pharmacological inactivation of selected signalling pathways, we demonstrated that T3 exerted its mitogenic effect on acinar cells via a tightly controlled action on different molecular effectors, including histone deacetylase, AKT, and TGFβ signalling.In conclusion, our data suggest that local availability of T3 in the pancreas is required to promote acinar cell proliferation and provide the rationale to exploit thyroid hormone signalling to enhance pancreatic regeneration

‘A Portrait of Lower Silesia’: Researching identity through collodion photography and memory narratives

In this article, I discuss a performance arts–based visual methodology based on the use of the archaic wet collodion photography. The collaboration between Street Collodion Art photography collective and myself, as a researcher, had two aims: to generate a large scale photographic and narrative portrait of Lower Silesia in Poland, and to explore identities in the region where nearly all of its inhabitants represent recent migrant populations. Data generated through this project include collodion portraits, their interpretations and narratives collected through unstructured interviews. Initial data analysis has generated identity narratives linked to work, place and belonging and ethnicity/nationality. In addition, in 2016 and 2017, three exhibitions of the portraits and a selection of edited stories took place in Lubin, Legnica and Wrocław attended by local inhabitants, including project participants. The examination of the arts-based methodology finds that the ritual character of the wet collodion photographic encounter has acted as a form of artistic intervention which, in generating memory narratives, enabled an articulation of social identities in the climate dominated by nationalist discourses. Such symbolic work emerging out of the project reveals a critical potential in the collaboration between the arts and social research. Furthermore, the project has shown that despite different traditions of practice, a collaboration between the artists and social researchers can yield rich data and access participants in ways that conventional methodologies cannot

Mitochondrial respiratory states and rate

As the knowledge base and importance of mitochondrial physiology to human health expands, the necessity for harmonizing the terminologyconcerning mitochondrial respiratory states and rates has become increasingly apparent. Thechemiosmotic theoryestablishes the mechanism of energy transformationandcoupling in oxidative phosphorylation. Theunifying concept of the protonmotive force providestheframeworkfordeveloping a consistent theoretical foundation ofmitochondrial physiology and bioenergetics.We followguidelines of the International Union of Pure and Applied Chemistry(IUPAC)onterminology inphysical chemistry, extended by considerationsofopen systems and thermodynamicsof irreversible processes.Theconcept-driven constructive terminology incorporates the meaning of each quantity and alignsconcepts and symbols withthe nomenclature of classicalbioenergetics. We endeavour to provide a balanced view ofmitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes.Uniform standards for evaluation of respiratory states and rates will ultimatelycontribute to reproducibility between laboratories and thussupport the development of databases of mitochondrial respiratory function in species, tissues, and cells.Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery

Mitochondrial physiology

As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery

Mitochondrial physiology

As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery

On the Peripheries of Memory: Tracing the History of the Old Jewish Cemetery in Wrocław’s Urban Imaginary1

The Old Jewish Cemetery in Wrocław offers a unique perspective on the changing tectonics of memory construction in a Central European city. In this article, we trace the little known history of the cemetery and the ways in which its position in the urban imaginary changed in the context of large‐scale geopolitical transformations. Through the cemetery’s history, we can follow the fate of one of the most prominent Jewish communities in pre‐World War II Germany, starting with its emergence following the emancipation of German Jews in the last quarter of the nineteenth century to its demise under Nazi rule. After the city’s transfer to Poland following the Potsdam Conference (1945), the cemetery became an increasingly isolated relic of the Jewish past of the city until its grassroots‐led revitalization commencing during the 1980s Solidarity era. After this important period of civic‐led renaissance tied to the city’s Jewish heritage, today, the cemetery has been pushed again to the periphery, an outcome of a process we refer to as the policy of memory containment

On the Peripheries of Memory: Tracing the History of the Old Jewish Cemetery in Wrocław’s Urban Imaginary1

The Old Jewish Cemetery in Wrocław offers a unique perspective on the changing tectonics of memory construction in a Central European city. In this article, we trace the little known history of the cemetery and the ways in which its position in the urban imaginary changed in the context of large‐scale geopolitical transformations. Through the cemetery’s history, we can follow the fate of one of the most prominent Jewish communities in pre‐World War II Germany, starting with its emergence following the emancipation of German Jews in the last quarter of the nineteenth century to its demise under Nazi rule. After the city’s transfer to Poland following the Potsdam Conference (1945), the cemetery became an increasingly isolated relic of the Jewish past of the city until its grassroots‐led revitalization commencing during the 1980s Solidarity era. After this important period of civic‐led renaissance tied to the city’s Jewish heritage, today, the cemetery has been pushed again to the periphery, an outcome of a process we refer to as the policy of memory containment

Central Europe Town Laboratories. Cities, memory and critical identities citizenship in international education.

In this article, we discuss the potential of cities and architectural environments as important spaces in conducting international education. Introducing La-Municipal boratoria of Central Europe, our proprietary methodological concept giving shape to the pedagogical activities we undertake in the context of education international, and more specifically as part of study programs abroad allows for American students staying at universities in Poland and Central Europe.We begin the description of this concept by considering the dimensions of the city that make it cities are currently playing a key role in international education as well as in practicalour pedagogy model. Then we explain in detail how it works they include Municipal Laboratories, citing specific examples taken from them from our work with student