52 research outputs found
Don’t Split Them Up! Landscape Design of Multifunctional Open Spaces Suitable for Coping with Flash Floods and River Floods
Pressures arising from agriculture, infrastructures and settlements have gradually reduced natural spaces of European watercourses limiting their self-regulation capacities, environmental and social potentials, resulting in widespread critical anthropic features. Dealing with flood phenomena adds artificiality, as several works for hydraulic protection are necessary. This was the case of Pistoia, a small city in the north of Tuscany, where the Ombrone stream, held in a straight-channeled course since the 18th century, sometimes breaks its embankments and floods the low plain from the southeast of Pistoia to downstream. Complying with the EU Floods Directive (2007/60/EC), the regional authority for flood risks planned some basins in the high plain upstream of Pistoia. A study we developed before this research assumed to shift the design approach from functional separation to full integration of hydraulic works in an area planned as an urban park for several years, but still in waiting. We now carried out a second study that adopts the concept of deep structure as the main design reference to “see” the park in the landscape features. This article concerns the research by the design process just developed to investigate a sustainable layout of the place new hydraulic asset as a basic landscape identity of the future park. Not to split spaces up with regard to their main functions was the general aim the process was focused on to combine an effective hydraulic protection with a full environmental and social enhancement of the urban park
Public Food Procurement: A Systematic Literature Review
Public food procurement (PFP) is a policy instrument that has been used to “link” different objectives at once. We undertake a first systematic review of the scientific literature that deals with PFP in order to 1.) assess the progress of the scientific literature concerning PFP in different areas of the world, 2.) look for differences among them and try to identify the topics on which these studies focuses the most. Accordingly, our research questions deal with the definition of the main conceptual dimensions developed by the academic literature on PFP as well as with the geographical and temporal differences among the dimensions identified. The first evidence is the increase in the number of papers per year during the last decade. Furthermore, the literature on PFP is centred on the concepts of localisation and structured demand and its impacts on food chain actors, on citizen-consumers and on sustainability at large. As a main research result, we provide a conceptual framework of the PFP literature largely based on the concept of linkage that has been first proposed in law and regulation studies
The WaveDAQ integrated Trigger and Data Acquisition System for the MEG II experiment
The WaveDAQ is a newly-designed digitization Trigger and Data AcQuisition
system (TDAQ) allowing Multi-gigasample waveform recording on a large amount of
channels (up to 16384) by using the DRS4 analog switched capacitor array as
downconverting ASIC. A high bandwidth, programmable input stage has been
coupled with a bias generator to allow SiPM operation without need of any other
external apparatus. The trigger generation is tightly coupled within the system
to limit the required depth of the analog memory, allowing faster digitization
speeds. This system has been designed for the MEG experiment upgrade but also
proved to be highly scalable and already found other applications.Comment: This manuscript is for conference record of the 21st IEEE Real Time
conference onl
Comparison and combination of a hemodynamics/biomarkers-based model with simplified PESI score for prognostic stratification of acute pulmonary embolism: findings from a real world study
Background: Prognostic stratification is of utmost importance for management of acute Pulmonary Embolism (PE) in clinical practice. Many prognostic models have been proposed, but which is the best prognosticator in real life remains unclear. The aim of our study was to compare and combine the predictive values of the hemodynamics/biomarkers based prognostic model proposed by European Society of Cardiology (ESC) in 2008 and simplified PESI score (sPESI).Methods: Data records of 452 patients discharged for acute PE from Internal Medicine wards of Tuscany (Italy) were analysed. The ESC model and sPESI were retrospectively calculated and compared by using Areas under Receiver Operating Characteristics (ROC) Curves (AUCs) and finally the combination of the two models was tested in hemodinamically stable patients. All cause and PE-related in-hospital mortality and fatal or major bleedings were the analyzed endpointsResults: All cause in-hospital mortality was 25% (16.6% PE related) in high risk, 8.7% (4.7%) in intermediate risk and 3.8% (1.2%) in low risk patients according to ESC model. All cause in-hospital mortality was 10.95% (5.75% PE related) in patients with sPESI score ≥1 and 0% (0%) in sPESI score 0. Predictive performance of sPESI was not significantly different compared with 2008 ESC model both for all cause (AUC sPESI 0.711, 95% CI: 0.661-0.758 versus ESC 0.619, 95% CI: 0.567-0.670, difference between AUCs 0.0916, p=0.084) and for PE-related mortality (AUC sPESI 0.764, 95% CI: 0.717-0.808 versus ESC 0.650, 95% CI: 0.598-0.700, difference between AUCs 0.114, p=0.11). Fatal or major bleedings occurred in 4.30% of high risk, 1.60% of intermediate risk and 2.50% of low risk patients according to 2008 ESC model, whereas these occurred in 1.80% of high risk and 1.45% of low risk patients according to sPESI, respectively. Predictive performance for fatal or major bleeding between two models was not significantly different (AUC sPESI 0.658, 95% CI: 0.606-0.707 versus ESC 0.512, 95% CI: 0.459-0.565, difference between AUCs 0.145, p=0.34). In hemodynamically stable patients, the combined endpoint in-hospital PE-related mortality and/or fatal or major bleeding (adverse events) occurred in 0% of patients with low risk ESC model and sPESI score 0, whilst it occurred in 5.5% of patients with low-risk ESC model but sPESI ≥1. In intermediate risk patients according to ESC model, adverse events occurred in 3.6% of patients with sPESI score 0 and 6.65% of patients with sPESI score ≥1.Conclusions: In real world, predictive performance of sPESI and the hemodynamic/biomarkers-based ESC model as prognosticator of in-hospital mortality and bleedings is similar. Combination of sPESI 0 with low risk ESC model may identify patients with very low risk of adverse events and candidate for early hospital discharge or home treatment.
Molecular Markers, Paraneoplastic Syndrome, and Inferior Vena Cava Involvement as Risk Factors for Renal Tumor Recurrence
Efficacy of thromboprophylaxis during pregnancy in women with a previous cerebral vein thrombosis
- …