38 research outputs found
Monopoles, confinement and deconfinement of (2+1)D compact lattice QED in external fields
The compact Abelian model in three space--time dimensions is studied in the
presence of external electromagnetic fields at finite temperatures. We show
that the deconfinement phase transition is independent on the strength of the
external fields. This result is in agreement with our observation that the
external fields create small--size magnetic dipoles from the vacuum which do
not influence the confining properties of the model. Contrary to the
deconfinement phase, the internal field in the direction of the applied
external field is attenuated in the confinement phase, this screening becomes
stronger with decreasing temperature.Comment: 22 pages, 24 EPS figures, LaTeX uses epsfig.st
“Plug and play” modular façade construction system for building renovation to achieve nearly Zero Energy Building (nZEB)
Following energy performance improvement policies, there is a need for the massive renovation of the European building stock. The prevalence of multi-rise buildings with concrete structure and poor thermal performance offers a significant opportunity for renovation packages that facilitate the improvement of the building fabric, with its insulation, air-tightness and integration of building services and solar technologies. The RenoZEB project develops a "plug and play" modular facade construction system answering to this need. This prefabricated plug and play modular system has been tested by reproducing the holistic methodology and new technologies in the market by means of real and virtual demonstrators. The applicability and effectiveness of the methodology has been tested by means of a full-scale mock-up system has been constructed and installed in the KUBIK by Tecnalia test facility. The design, construction, manufacture & installation cycle has been tested. Its applicability for a real construction project for a multi-rise residential building in Spain is presented.This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 768718
Economic impact of improving patient safety using Sugammadex for routine reversal of neuromuscular blockade in Spain
Background: Neuromuscular blocking (NMB) agents are often administered to facilitate tracheal intubation and prevent patient movement during surgical procedures requiring the use of general anesthetics. Incomplete reversal of NMB, can lead to residual NMB, which can increase the risk of post-operative pulmonary complications. Sugammadex is indicated to reverse neuromuscular blockade induced by rocuronium or vecuronium in adults. The aim of this study is to estimate the clinical and economic impact of introducing sugammadex to routine reversal of neuromuscular blockade (NMB) with rocuronium in Spain.
Methods: A decision analytic model was constructed reflecting a set of procedures using rocuronium that resulted in moderate or deep NMB at the end of the procedure. Two scenarios were considered for 537, 931 procedures using NMB agents in Spain in 2015: a scenario without sugammadex versus a scenario with sugammadex. Comparators included neostigmine (plus glycopyrrolate) and no reversal agent. The total costs for the healthcare system were estimated from the net of costs of reversal agents and overall cost offsets via reduction in postoperative pneumonias and atelectasis for which incidence rates were based on a Spanish real-world evidence (RWE) study. The model time horizon was assumed to be one year. Costs were expressed in 2019 euros (€) and estimated from the perspective of a healthcare system. One-way sensitivity analysis was carried out by varying each parameter included in the model within a range of +/- 50%.
Results: The estimated budget impact of the introduction of sugammadex to the routine reversal of neuromuscular blockade in Spanish hospitals was a net saving of €57.1 million annually. An increase in drug acquisition costs was offset by savings in post-operative pulmonary events, including 4806 post-operative pneumonias and 13, 996 cases of atelectasis. The total cost of complications avoided was €70.4 million. All parameters included in the model were tested in sensitivity analysis and were favorable to the scenario with sugammadex.
Conclusions: This economic analysis shows that sugammadex can potentially lead to cost savings for the reversal of rocuronium-induced moderate or profound NMB compared to no reversal and reversal with neostigmine in the Spanish health care setting. The economic model was based on data obtained from Spain and from assumptions from clinical practice and may not be valid for other countries
The monopole mass in the three-dimensional Georgi-Glashow model
We study the three-dimensional Georgi-Glashow model to demonstrate how
magnetic monopoles can be studied fully non-perturbatively in lattice Monte
Carlo simulations, without any assumptions about the smoothness of the field
configurations. We examine the apparent contradiction between the conjectured
analytic connection of the `broken' and `symmetric' phases, and the
interpretation of the mass (i.e., the free energy) of the fully quantised 't
Hooft-Polyakov monopole as an order parameter to distinguish the phases. We use
Monte Carlo simulations to measure the monopole free energy and its first
derivative with respect to the scalar mass. On small volumes we compare this to
semi-classical predictions for the monopole. On large volumes we show that the
free energy is screened to zero, signalling the formation of a confining
monopole condensate. This screening does not allow the monopole mass to be
interpreted as an order parameter, resolving the paradox.Comment: 12 pages, 7 figures, uses revtex. Minor changes made to the text to
match with the published version at
http://link.aps.org/abstract/PRD/v65/e12500
Establishing the health and wellbeing needs of mining host community in Brazil, Chile and Peru: a mixed-method approach to identify priority areas for action to help communities meet their SDG3 targets
Background
The global mining industry is an important partner in advancing the 2030 Agenda for Sustainable Development. In 2018, Anglo American plc published their Sustainable Mining Plan, containing a goal for improving health and wellbeing aligned with the Sustainable Development Goal 3 (SDG3) targets. Having formed an independent multidisciplinary research consortium, we designed and implemented a mixed-methods approach to attain a deeper understanding of SDG3 priorities within the local context of communities hosting Anglo American mining operations located in Latin America.
Methods
In 2019, within the host communities of three mining operations in Chile, three in Brazil, and one in Peru, we conducted a qualitative study which included stakeholder workshops and key informant interviews. We also quantitatively appraised existing health data. Findings emerging from the qualitative and quantitative assessments were compared to identify health and wellbeing priority areas for action relevant to each community.
Results
Across the three countries, 120 people took part in workshops and 35 in interviews. In these workshops and interviews, non-communicable diseases (SDG3.4), harmful alcohol consumption (SDG3.5), and pollution, particularly air pollution (SDG3.9), were consistently identified as areas for priority action. There were similarities in the reporting of individual, interpersonal, community, societal, and structural factors underlying these priority areas across the different communities. The availability of quantitative data was generally good at the state level, becoming increasing sparse as we focused on smaller geographies. The priorities identified in the quantitative assessments generally aligned with those highlighted in the qualitative data.
Conclusions
We highlight the importance of engaging with local populations to understand and address health needs. To address the priorities identified, intervention packages tailored to the specific needs of host communities, that tackle associated upstream societal level factors, are required. To facilitate this, appropriate monitoring systems and epidemiological investigations should be implemented to better understand the local context and quantify health issues. In the host communities, it is essential for the mining sector to be a key health partner in promoting integrated programmes that contribute to achieving the priority objectives and targets aligned with the SDG3 agenda
Olber's Paradox for Superluminal Neutrinos: Constraining Extreme Neutrino Speeds at TeV-ZeV Energies with the Diffuse Neutrino Background
The only invariant speed in special relativity is c; therefore, if some
neutrinos travel at even tiny speeds above c, normal special relativity is
incomplete and any superluminal speed may be possible. I derive a limit on
superluminal neutrino speeds v >> c at high energies by noting that such speeds
would increase the size of the neutrino horizon. The increased volume of the
Universe visible leads to a brighter astrophysical neutrino background. The
nondetection of "guaranteed" neutrino backgrounds from star-forming galaxies
and ultrahigh energy cosmic rays (UHECRs) constrains v/c at TeV--ZeV energies.
I find that v/c <= 820 at 60 TeV from the nondetection of neutrinos from
star-forming galaxies. The nondetection of neutrinos from UHECRs constrains v/c
to be less than 2500 at 0.1 EeV in a pessimistic model and less than 4.6 at 4
EeV in an optimistic model. The UHECR neutrino background nondetection is
strongly inconsistent with a naive quadratic extrapolation of the OPERA results
to EeV energies. The limits apply subject to some caveats, particularly that
the expected pionic neutrino backgrounds exist and that neutrinos travel faster
than c when they pass the detector. They could be improved substantially as the
expected neutrino backgrounds are better understood and with new experimental
neutrino background limits. I also point out that extremely subluminal speeds
would result in a much smaller neutrino background intensity than expected.Comment: 13 pages, 2 figures, fixed titl
Quark Matter in a Strong Magnetic Background
In this chapter, we discuss several aspects of the theory of strong
interactions in presence of a strong magnetic background. In particular, we
summarize our results on the effect of the magnetic background on chiral
symmetry restoration and deconfinement at finite temperature. Moreover, we
compute the magnetic susceptibility of the chiral condensate and the quark
polarization at zero temperature. Our theoretical framework is given by chiral
models: the Nambu-Jona-Lasinio (NJL), the Polyakov improved NJL (or PNJL) and
the Quark-Meson (QM) models. We also compare our results with the ones obtained
by other groups.Comment: 34 pages, survey. To appear in Lect. Notes Phys. "Strongly
interacting matter in magnetic fields" (Springer), edited by D. Kharzeev, K.
Landsteiner, A. Schmitt, H.-U. Ye