Estado clínico, adherencia al TARGA y calidad de vida en pacientes con infección por el VIH tratados con antirretrovirales

Introduction: Quality of life is one of the most frequently used subjective measures in chronic health problems. The aim of this study is to analyze the association between clinical and therapeutic parameters, and 11 quality of life domains in HIV-infected patients. Methods: A cross-sectional survey of 320 patients on antiretroviral treatment was conducted in four Andalusian hospitals (Spain). A semi-structured questionnaire was administered by health care professionals. Health-related quality of life was assessed with the MOS-HIV questionnaire, an instrument designed specifically for HIV-infected patients. Results: Almost three-quarters of the population were men (73.4%); 35.6% had developed aids, and 88.1% were considered adherent to treatment. Patients with greater viral load presented lower quality of life scores for all the domains, except cognitive functioning. Patients who had developed aids showed poorer quality of life for 10 of the 11 domains. Patients with adequate adherence to antiretroviral treatment showed better quality of life for 10 domains. No statistically significant differences in the domain scores except for quality of life were found between patients with a treatment regimen including protease inhibitors and those without. Conclusion: The patient's clinical status and adherence affect not only survival, but also quality of lif

Impacto del apoyo social y la morbilidad psíquica en la calidad de vida en pacientes tratados con antirretrovirales

Journal articleThe impact of the social support and the psychic morbidity on the quality of life of patients with antiretroviral therapy. The aim of this study is to analyse the existing relation between the psychic morbidity and social support and the quality of life. Besides this, the paper analyses the buffer rol that social support plays on the psychic morbidity in these patients. We studied 320 HIV+ patients in truatment with antiretrovirals, who attended the infectious disease services of four hospitals of the Autonomous Andalusian Community. Being associated a better quality of life to an absence of psychic morbidity and to the presence of social support, it is observed the relevant buffer role that the social support like shock absorber of the psychic morbidity in this one type of patients. These results show the importance that the psycho-social factors have during the course of chronic diseases.Trabajo subvencionado por la Consejería de Salud de la Junta de AndalucÌa. Exp. número 01/254 y parcialmente por la Red Temática en Epidemiología y Salud Pública (C03/09).YesEl objeto de este estudio es analizar la relaciÛn existente entre la morbilidad psÌquica y el apoyo social con la calidad de vida. Por otro, el papel que realiza el apoyo social como amortiguador de la morbilidad psÌquica en estos pacientes. Se estudiaron a 320 pacientes VIH positivos en tratamiento con antirretrovirales, que acudieron a las consultas externas del servicio de infecciosos de cuatro hospitales de la comunidad autÛnoma andaluza. AsÌ, una mejor calidad de vida se asociÛ a una ausencia de morbilidad psÌquica y a la presencia de apoyo social, a la vez que se observa el papel fundamental que juega el apoyo social como amortiguador de la morbilidad psÌquica en este tipo de pacientes. Estos resultados ponen de relieve la importancia que los factores psicosociales tienen durante el transcurso de enfermedades de car·cter crÛnico