The Influence of an Orienting Task on the Memory Performance of Children with Reading Problems

This study investigated the hypothesis that differences in performance between reading disabled and normal children on a rote memory task could be eliminated if both groups were induced to process the material to be remembered in the same manner. The free recall of fourth-grade good and poor readers was tested following a free study period and the performance of an orienting task that required subjects to sort the material into taxonomic categories. There was a significant group by conditions interaction, with recall differences in the free study condition being eliminated following performance of the orienting task. The results have important implications for theoretical explanations of performance deficits in reading disabled children.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68893/2/10.1177_002221947901200608.pd

A programming interface and framework for developing recommendation algorithms on large-scale social networks

Friend recommendation algorithms in large-scale social networks such as Facebook or Twitter usually require the exploration of huge user graphs. In current solutions for parallelizing graph algorithms, the burden of dealing with distributed concerns falls on algorithm developers. In this paper, a simple yet powerful programming interface (API) to implement distributed graph traversal algorithms is presented. A case study on implementing a followee recommendation algorithm for Twitter using the API is described. This case study not only illustrates the simplicity offered by the API for developing algorithms, but also how different aspects of the distributed solutions can be treated and experimented without altering the algorithm code. Experiments evaluating the performance of different job scheduling strategies illustrate the flexibility or our approach.Fil: Corbellini, Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tandil. Instituto Superior de Ingenieria del Software; ArgentinaFil: Godoy, Daniela Lis. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tandil. Instituto Superior de Ingenieria del Software; ArgentinaFil: Mateos Diaz, Cristian Maximiliano. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tandil. Instituto Superior de Ingenieria del Software; ArgentinaFil: Zunino Suarez, Alejandro Octavio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tandil. Instituto Superior de Ingenieria del Software; ArgentinaFil: Schiaffino, Silvia Noemi. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tandil. Instituto Superior de Ingenieria del Software; Argentin

Human breast cancer cell metastasis to long bone and soft organs of nude mice : a quantitative assay

Bone is a common metastatic site in human breast cancer (HBC). Since bone metastasis occurs very rarely from current spontaneous or experimental metastasis models of HBC cells in nude mice, an arterial seeding model involving the direct injection of the cells into the left ventricle has been developed to better understand the mechanisms involved in this process. We present here a sensitive polymerase chain reaction (PCR) method to detect and quantitate bone and soft organ metastasis in nude mice which have been intracardially inoculated with Lac Z transduced HBC cells. Amplification of genomically incorporated Lac Z sequences in MDA-MB-231-BAG HBC cells enables us to specifically detect these cells in mouse organs and bones. We have also created a competitive template to use as an internal standard in the PCR reactions, allowing us to better quantitate levels of HBC metastasis. The results of this PCR detection method correlate well with cell culture detection from alternate long bones from the same mice, and are more sensitive than gross Lac Z staining with X-gal or routine histology. Comparable qualitative results were obtained with PCR and culture in a titration experiment in which mice were inoculated with increasing numbers of cells, but PCR is more quantifiable, less time consuming, and less expensive. This assay can be employed to study the molecular and cellular aspects of bone metastasis, and could easily be used in conjunction with RT-PCR-based analyses of gene products which may be involved with HBC metastasis