Additional file 1: of Impairment of early fracture healing by skeletal muscle trauma is restored by FK506

Representative image presenting selection of region for immunohistochemistry analysis. Quantitative analysis of CD4, CD8, and CD68 was conducted off of the whole bone section (A) by selecting the region of the callus (B). In all instances the callus region was traced in the area between the bone ends on the anterior aspect of the tibia without selection of mineralized bone or skeletal muscle fibers. C) The selected representative image corresponds to the image in Fig. 6 for reference. (PDF 3305 kb

Search strategy.

<p>Search strategy.</p

Meta-analysis of the risk of developing at least one major pneumonia sequela in children under five years by hospitalisation status and pathogenic cause, 1970–2011.

<p>Meta-analysis of the risk of developing at least one major pneumonia sequela in children under five years by hospitalisation status and pathogenic cause, 1970–2011.</p

Characteristics of included studies, 1970–2011.

<p>Characteristics of included studies, 1970–2011.</p

Pneumonia case definitions.

<p>Pneumonia case definitions.</p

Major pneumonia sequelae risk, by site and pathogen, 1970–2011.

<p>95%CI = 95% confidence interval.</p

Sequelae domains and case definitions.

<p>GBD = Global Burden of Disease Project.</p><p>ICD10 = International Classification of Diseases, 10th edition.</p><p>FVC  =  Forced vital capacity (FVC).</p><p>FEV1  =  Forced expiratory volume in 1 second.</p

Regression analyses of the effect of explanatory variables on major pneumonia sequelae risk in children under five years, 1970–2011.

<p>*Adjusted for pathogenic cause of pneumonia, hospitalisation status, loss to followup.</p

Thiamine diphosphate and chromium in cases, controls and Tarawa participants, 2015.

<p>Thiamine diphosphate and chromium in cases, controls and Tarawa participants, 2015.</p

Monthly cases of confirmed and unconfirmed thiamine deficiency disease by month and year of symptom onset on Kuria, Kiribati, during the period from 1 October 2012 to 13 February 2015.

<p>Monthly cases of confirmed and unconfirmed thiamine deficiency disease by month and year of symptom onset on Kuria, Kiribati, during the period from 1 October 2012 to 13 February 2015.</p