15 research outputs found
Results of clinical laboratory tests and placental pathology for preterm birth cases.
*<p>Data presented as median [interquartile range] and analyzed by Kruskal-Wallis ANOVA.</p>†<p>Data presented as n (%) and analyzed by Chi square.</p><p><u>Abbreviations:</u> EONS, early-onset neonatal sepsis; IAI, intra-amniotic infection; LDH, lactate dehydrogenase; WBC, white blood cell; HCA, histological chorioamnionitis; ANC, absolute neutrophil count; ABC, absolute band count; I:T ratio, ratio of immature-to-total neutrophils.</p
Similarity of 16S rRNA gene sequences of the 13 common species shared between AF and CB from the same pregnancy.
*<p>Expressed in percent identity with number of identical bases/total bases in alignment shown in parentheses.</p
Accession numbers of 16S rRNA genes detected in matching amniotic fluid and cord blood samples by PCR and clone analysis.
*<p>Two subspecies of Fusobacterium nucleatum were identified. JN546083, F. nucleatum sbsp animalis; JN584646, F. nucleatum sbsp polymorphum.</p
Demographical, clinical and outcome characteristics of preterm birth cases.
*<p>Data presented as median [interquartile range] and analyzed by Kruskal-Wallis ANOVA.</p>†<p>Data presented as n (%) and analyzed by Chi square.</p><p><u>Abbreviations:</u> EONS, early-onset neonatal sepsis; IAI, intra-amniotic infection; PPROM, preterm premature rupture of membranes.</p
Alphabetical list of bacterial species identified by culture and culture-independent methods.
*<p>identified only by culture.</p>**<p>identified only by culture-independent methods.</p>***<p>Kappa coefficient is calculated for species identified in the paired AF-CB samples.</p
Summary of total number of species detected in amniotic fluid and cord blood by culture-dependent and independent methods.
*<p>Data presented as n (%).</p>†<p>Data presented as n.</p
Bacterial species identified in matching amniotic fluid, cord and neonatal blood samples by culture and/or culture-independent methods.<sup>*</sup>.
*<p>Results are shown for Groups 1 and 2. No bacterial DNA was detected in any samples in Groups 3 and 4. The species identified in more than one compartment are shown in <b>bold</b>.</p
Biomarker peaks in the 10–12.5 kDa hypervariable region (<i>Q-profile</i>).
<p>A: Five SELDI peaks (Q1–Q5 denoted by green arrows) in the 10–12.5 kDa mass region appeared in a subgroup of the SELDI tracings analyzed (Patients 1 and 2 are examples). The third tracing (Patient 3) shows the lack of biomarkers in a woman that delivered at term. R denotes a reference protein peak present in all fluid samples which corresponds to a fragment of beta-2 microglobulin. B: experimental masses (average and 95% confidence interval (95%CI) for the five biomarker components of the <i>Q-profile</i>.</p
Results of amniotic fluid analysis
†<p>Data presented as median [interquartile range] and analyzed by Kruskal-Wallis ANOVA.</p>‡<p>Data presented as n (%) and analyzed by Chi square.</p
Classification of the amniotic fluid proteome dys-regulated in samples expressing the <i>Q-profile</i> using the PANTHER biological process classification system.
<p>Classification of the amniotic fluid proteome dys-regulated in samples expressing the <i>Q-profile</i> using the PANTHER biological process classification system.</p