NEOTROPICAL XENARTHRANS: a data set of occurrence of xenarthran species in the Neotropics

Xenarthrans – anteaters, sloths, and armadillos – have essential functions for ecosystem maintenance, such as insect control and nutrient cycling, playing key roles as ecosystem engineers. Because of habitat loss and fragmentation, hunting pressure, and conflicts with 24 domestic dogs, these species have been threatened locally, regionally, or even across their full distribution ranges. The Neotropics harbor 21 species of armadillos, ten anteaters, and six sloths. Our dataset includes the families Chlamyphoridae (13), Dasypodidae (7), Myrmecophagidae (3), Bradypodidae (4), and Megalonychidae (2). We have no occurrence data on Dasypus pilosus (Dasypodidae). Regarding Cyclopedidae, until recently, only one species was recognized, but new genetic studies have revealed that the group is represented by seven species. In this data-paper, we compiled a total of 42,528 records of 31 species, represented by occurrence and quantitative data, totaling 24,847 unique georeferenced records. The geographic range is from the south of the USA, Mexico, and Caribbean countries at the northern portion of the Neotropics, to its austral distribution in Argentina, Paraguay, Chile, and Uruguay. Regarding anteaters, Myrmecophaga tridactyla has the most records (n=5,941), and Cyclopes sp. has the fewest (n=240). The armadillo species with the most data is Dasypus novemcinctus (n=11,588), and the least recorded for Calyptophractus retusus (n=33). With regards to sloth species, Bradypus variegatus has the most records (n=962), and Bradypus pygmaeus has the fewest (n=12). Our main objective with Neotropical Xenarthrans is to make occurrence and quantitative data available to facilitate more ecological research, particularly if we integrate the xenarthran data with other datasets of Neotropical Series which will become available very soon (i.e. Neotropical Carnivores, Neotropical Invasive Mammals, and Neotropical Hunters and Dogs). Therefore, studies on trophic cascades, hunting pressure, habitat loss, fragmentation effects, species invasion, and climate change effects will be possible with the Neotropical Xenarthrans dataset

Silent, unknown and neglected, the HTLV requires massive investment in research

Submitted by Ana Maria Fiscina Sampaio ([email protected]) on 2019-02-25T12:15:19Z No. of bitstreams: 1 Entrevista.pdf: 142335 bytes, checksum: 7a2b71f7fbd6443986275c6cd1c83973 (MD5)Approved for entry into archive by Ana Maria Fiscina Sampaio ([email protected]) on 2019-02-25T12:30:41Z (GMT) No. of bitstreams: 1 Entrevista.pdf: 142335 bytes, checksum: 7a2b71f7fbd6443986275c6cd1c83973 (MD5)Made available in DSpace on 2019-02-25T12:30:41Z (GMT). No. of bitstreams: 1 Entrevista.pdf: 142335 bytes, checksum: 7a2b71f7fbd6443986275c6cd1c83973 (MD5) Previous issue date: 2019Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Em estimativa, o Brasil tem 2.5 milhões de pessoas infectadas pelo Vírus Linfortrópico da Célula-T Humana (HTLV). Para o pesquisador da Fiocruz Bahia, Bernardo Galvão, apesar dos riscos, a doença ainda é considerada pouco conhecida no Brasil até mesmo pelos profissionais de saúde. No Nordeste, foi observada alta prevalência nas cidades de Salvador, São Luís e Belém. Segundo dados da Secretaria de Saúde do Estado da Bahia (SESAB), houve um crescimento de 443% de casos no estado, entre 2013 e 2017, com destaque para Salvador, com 1084%. Coordenador do Centro de HTLV na Escola Bahiana de Medicina e Saúde Pública (EBMSP), Bernardo Galvão, em entrevista para a Sociedade Brasileira de Medicina Tropical (SBMT), destaca que, mesmo após quase 40 anos de pesquisa em HTLV, o tema não está em destaque nas discussões oficiais. Por isso, o pesquisador defendeu que a necessidade de inclusão de discussões nas agendas do Organização Mundial da Saúde (OMS) e no Ministério da Saúde

Associations among HTLV-I, HTLV-II, and HIV in injecting drug users in Salvador, Brazil.

Submitted by Ana Maria Fiscina Sampaio ([email protected]) on 2014-08-12T14:20:44Z No. of bitstreams: 1 Andrade TM Association among....pdf: 1583651 bytes, checksum: e4da5a55241466a882e65e523ea0bc22 (MD5)Made available in DSpace on 2014-08-12T14:20:44Z (GMT). No. of bitstreams: 1 Andrade TM Association among....pdf: 1583651 bytes, checksum: e4da5a55241466a882e65e523ea0bc22 (MD5) Previous issue date: 1998Centro de Estudos e Terapia do Abuso de Drogas - CETAD. Salvador, BA, BrasilUniversidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador, BA, Brasi

HIV-1 polymorphism: a challenge for vaccine development - a review

Submitted by Ana Maria Fiscina Sampaio ([email protected]) on 2013-01-24T20:55:04Z No. of bitstreams: 1 Morgado, M.G. HIV-1 polimorphism....pdf: 552704 bytes, checksum: f7af88a25c28d7b4d90dfdcbe09d56dd (MD5)Made available in DSpace on 2013-01-24T20:55:04Z (GMT). No. of bitstreams: 1 Morgado, M.G. HIV-1 polimorphism....pdf: 552704 bytes, checksum: f7af88a25c28d7b4d90dfdcbe09d56dd (MD5) Previous issue date: 2002Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador, BA, BrasilThe perspective for the development of anti-HIV/AIDS vaccines became a target sought by several research groups and pharmaceutical companies. However, the complex virus biology in addition to a striking genetic variability and the limited understanding of the immunological correlates of protection have made this an enormous scientific challenge not overcome so far. In this review we presented an updating of HIV-1 subtypes and recombinant viruses circulating in South American countries, focusing mainly on Brazil, as one of the challenges for HIV vaccine development. Moreover, we discussed the importance of stimulating developing countries to participate in the process of vaccine evaluation, not only testing vaccines according to already defined protocols, but also working together with them, in order to take into consideration their local information on virus diversity and host genetic background relevant for the vaccine development and testing, as well as including local virus based reagents to evaluate the immunogenicity of the candidate vaccines

Immune Complex Deposition in the Choroid Plexus of Patients with Acquired Immunodeficiency Syndrome

Submitted by Ana Maria Fiscina Sampaio ([email protected]) on 2016-07-08T18:14:29Z No. of bitstreams: 1 Falangola MF Immune complex....pdf: 401943 bytes, checksum: 6ca566ebe1f3967dfb946e0c68e2db69 (MD5)Approved for entry into archive by Ana Maria Fiscina Sampaio ([email protected]) on 2016-07-08T18:39:19Z (GMT) No. of bitstreams: 1 Falangola MF Immune complex....pdf: 401943 bytes, checksum: 6ca566ebe1f3967dfb946e0c68e2db69 (MD5)Made available in DSpace on 2016-07-08T18:39:19Z (GMT). No. of bitstreams: 1 Falangola MF Immune complex....pdf: 401943 bytes, checksum: 6ca566ebe1f3967dfb946e0c68e2db69 (MD5) Previous issue date: 1994Made available in DSpace on 2016-07-22T13:10:49Z (GMT). No. of bitstreams: 3 Falangola MF Immune complex.pdf.txt: 17730 bytes, checksum: d0ef63caf44bac15f4ca352e64678441 (MD5) Falangola MF Immune complex.pdf: 401943 bytes, checksum: 6ca566ebe1f3967dfb946e0c68e2db69 (MD5) license.txt: 2991 bytes, checksum: 5a560609d32a3863062d77ff32785d58 (MD5) Previous issue date: 1994Fundação Gonçalo Moniz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilFundação Gonçalo Moniz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilUniversity of Miami School of Medicine. Department of Pathology. Miami, Floridaplexus of approximately 75% of patients with acquired immunodeficiency syndrome (AIDS) who had either normal brains or human immunodeficiency virus encephalitis. Since circulating immune complexes are common in AIDS patients, and since local choroid plexus pathology usually was absent, their likely origin is from the bloodstream. Choroid plexus deposits of immune complexes have been implicated in altering the function of this structure or in enhancing its vulnerability to infection. Therefore, immune complex deposition in the choroid plexus of AIDS patients may be responsible for some of the common alterations in the cerebrospinal fluid and for the frequency of opportunistic infections in this region

Increasing awareness of human T-lymphotropic virus type-1 infection: a serious, invisible, and neglected health problem in Brazil

Submitted by Ana Maria Fiscina Sampaio ([email protected]) on 2019-11-14T13:38:40Z No. of bitstreams: 1 Sohler, P. Increasing....pdf: 857491 bytes, checksum: fb4694ff14ff1978aad722a65539cdb7 (MD5)Approved for entry into archive by Ana Maria Fiscina Sampaio ([email protected]) on 2019-11-14T13:54:10Z (GMT) No. of bitstreams: 1 Sohler, P. Increasing....pdf: 857491 bytes, checksum: fb4694ff14ff1978aad722a65539cdb7 (MD5)Made available in DSpace on 2019-11-14T13:54:10Z (GMT). No. of bitstreams: 1 Sohler, P. Increasing....pdf: 857491 bytes, checksum: fb4694ff14ff1978aad722a65539cdb7 (MD5) Previous issue date: 2019Universidade Federal do Estado do Rio de Janeiro. Escola de Medicina e Cirurgia. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Programa de Pós-Graduação em Doenças Infecciosas e Parasitárias. Rio de Janeiro, RJ, Brasil.Escola Bahiana de Medicina. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Escola Bahiana de Medicina. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Human T-lymphotropic virus type 1 (HTLV-1) was the first retrovirus to be isolated in humans. At least 5–10 million individuals harbor the virus worldwide1. In Brazil, between 800,000 and 2.5 million individuals are infected with HTLV-11,2. The geographic distribution of infection is heterogenous in this country and more pronounced in the North and Northeast, mainly affecting low-income populations2,3. One of the few studies that attempted to estimate the prevalence of infection in a general population was conducted in the city of Salvador, reported to be approximately 1.8%3. Most studies involving Brazilian populations have been performed in specific groups, such as blood donors or pregnant women, and the prevalence in the overall population remains unknown4

Imunossupressão em indivíduos infectados pelo HTLV: possíveis mecanismos imunológicos

Submitted by Ana Maria Fiscina Sampaio ([email protected]) on 2014-07-28T14:07:00Z No. of bitstreams: 1 Grassi MFR Imunossupressao....pdf: 127935 bytes, checksum: e49037ce7af300f309204d8a42047e53 (MD5)Made available in DSpace on 2014-07-28T14:07:00Z (GMT). No. of bitstreams: 1 Grassi MFR Imunossupressao....pdf: 127935 bytes, checksum: e49037ce7af300f309204d8a42047e53 (MD5) Previous issue date: 2009Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador, BA, Brasil / Escola Bahiana de Medicina e Saúde Pública. Salvador, BA, BrasilO vírus linfotrópico de células T humanas do tipo 1 (HTLV-I) é o agente etiológico da leucemia/linfoma de células T do adulto (ATL) e da paraparesia espástica tropical/mielopatia associada ao HTLV (HAM/TSP), e está associado a diversas patologias inflamatórias como uveítes, artrites, polimiosites. Além disso, uma maior morbidade e mortalidade de doenças infecciosas, como estrongiloidíase disseminada e tuberculose, é observada em indivíduos co-infectados, sugerindo um grau de imunossupressão. Uma das características imunológicas da infecção pelo HTLV é a proliferação espontânea, in vitro, das células mononucleares do sangue periférico (PBMC), além de elevada produção de citocinas inflamatórias como IFN-γ, TNF-α de IL-10 e IL-2 e maior expressão de moléculas de ativação em linfócitos T. Nesta revisão serão discutidos o papel da ativação celular e da proliferação espontânea sobre a resposta celular contra antígenos de memória.Human T lymphotropic virus type 1 (HTLV-I) is the etiologic agent of adult T-cell leukemia lymphoma (ATLL) and HTLVI associated myelopathy/ tropical spastic paraparesis (HAM/TSP), and is associated with several inflammatory diseases such as uveitis, arthritis, polymyositis. Moreover, increased morbidity and mortality of infectious diseases such as disseminated strongyloidiasis and tuberculosis is observed in co-infected individuals, suggesting a degree of immunosuppression. One of the immunological halmarker of HTLV infection is the spontaneous proliferation of peripheral blood mononuclear cells (PBMC), in vitro, in addition to a high production of inflammatory cytokines such as IFN-γ, TNF-α, IL-10 and IL- 2 and high expression of activation molecules on T lymphocytes. This review will discuss the role of both cellular activation and spontaneous proliferation in cellular immune response against recall antigens

Implementation of the "Projeto Nascer Maternidades" in a reference maternity of the city of Feira de Santana, Satate of Bahia, Brazil

Castro Filho, Bernardo Galvão; Grassi, Maria Fernanda Rios “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”.Submitted by Ana Maria Fiscina Sampaio ([email protected]) on 2017-06-19T14:17:59Z No. of bitstreams: 1 Santos NP Aplicacao do protocolo....pdf: 111135 bytes, checksum: 2d440b1a5b3fb0cf404cbe3f1dc00692 (MD5)Approved for entry into archive by Ana Maria Fiscina Sampaio ([email protected]) on 2017-06-19T16:22:22Z (GMT) No. of bitstreams: 1 Santos NP Aplicacao do protocolo....pdf: 111135 bytes, checksum: 2d440b1a5b3fb0cf404cbe3f1dc00692 (MD5)Made available in DSpace on 2017-06-19T16:22:22Z (GMT). No. of bitstreams: 1 Santos NP Aplicacao do protocolo....pdf: 111135 bytes, checksum: 2d440b1a5b3fb0cf404cbe3f1dc00692 (MD5) Previous issue date: 2009Escola Bahiana de Medicina e Saúde Pública. Salvador, BA, BrasilEscola Bahiana de Medicina e Saúde Pública. Salvador, BA, BrasilEscola Bahiana de Medicina e Saúde Pública. Salvador, BA, BrasilObjetivos: analisar a aplicação do protocolo do "Projeto Nascer Maternidades", estratégia do Ministério da Saúde para a adoção de medidas profiláticas e/ou terapêuticas no momento do parto, para gestantes com sorologias para sífilis/Aids desconhecidas no primeiro ano de implantação em uma maternidade de referência em Feira de Santana, Bahia, Brasil. Métodos: foram analisadas sorologias para HIV e sífilis solicitadas no pré-natal e na maternidade e a adoção de medidas profiláticas e/ou terapêuticas. Os dados foram coletados em uma amostra randomizada de 337 prontuários de gestantes admitidas para assistência obstétrica no período de julho de 2003 a julho de 2004. Resultados: no pré-natal, 8,4% das gestantes realizaram sorologia para HIV e 8% para sífilis. Na maternidade, o teste rápido para HIV foi realizado para 17,7% das gestantes e o VDRL para 97,8%. A profilaxia das gestantes infectadas pelo HIV foi aplicada no momento do parto. Quanto à sífilis, não houve tratamento para 80% das mulheres com VDRL reagente. Os recém-nascidos foram tratados. Conclusões: as determinações do "Projeto Nascer-Maternidades" não foram seguidas no primeiro ano de implantação na maternidade estudada