Estudio de las Escuelas Universitarias de Ingeniería Técnica

Estudio de la problemática de las Escuelas Universitarias de Ingenieria Técnica para enmarcarlo dentro del contexto de posibles renovaciones educativas, contando con las opiniones de los estamentos docente y discente. Muestra compuesta por 1792 alumnos matriculados en las Escuelas de Ingenieria Técnica de Cataluña, curso 1976-77. Varios profesores de diversas Escuelas de Ingeniería Técnica de Cataluña. En la primera parte se presenta una introducción que situa el contexto socio-económico en que se hallan insertas estas escuelas. A continuación se ofrece una visión del marco histórico de este tipo de enseñanza en Cataluña. Y la muestra es la evolución del alumnado desde el período 1960-78. Se presentan las estructuras de las enseñanzas técnicas en enseñanzas universitarias y Europa con el punto de vista de la OCDE y CEE como aportación al estudio comparado y observación de soluciones dadas. Se pasa una encuesta a alumnos de estas enseñanzas, aportando datos sobre variables inddpendientes (edad, sexo, etc.) y su correlación con el grado de satisfacción, las áreas de influencia de estas escuelas y el punto de vista de su profesorado sobre la problemática estudiada. La evolución del alumnado oficial a partir de 1960 es creciente hasta llegar a su máximo en 1961-62, e iniciándose un descenso que seguirá hasta el curso 1972-73. A partir de 73-74 puede hablarse de una revitalización de estas escuelas. La CEE y la OCDE tienen una clasificación que responde, en el primer caso, a las enseñanzas técnicas en función de los objetivos profesionales; la OCDE, por su parte, realiza una clasificación para la Enseñanza Superior corta que responde a la existente en los diversos países occidentales. El estudio del alumnado: predominantemente masculino, menores de 23 años, de nivel socio-económico medio o medio-bajo. La mayoría trabaja y la mitad contesta que estudian en este tipo de centros por necesidad económica más que por vocación. Los alumnos no están satisfechos. Las correlaciones entre grado de satisfacción y sexo y nivel socio-profesional del padre no han dado resultados. Profesorado: no existe selección. Posibilidades de promoción mínimas. Imposibilidad de realizar investigaciones. Aislamiento. Insatisfacción. El principal objetivo a resolver será el buscar el equilibrio entre una formación de un nivel que posibilite a los profesionales de estas carreras ejercer en campos tecnológicos elevados, y una formación práctica que permita incorporarse en el campo de la producción.CataluñaBiblioteca de Educación del Ministerio de Educación, Cultura y Deporte; Calle San Agustín, 5 - 3 Planta; 28014 Madrid; Tel. +34917748000; Fax +34917748026; [email protected]

Transmitting the industrial city / Trasmettere la città industriale

Introduzione alla Main Session "Trasmettere città industriale", nel XXIII UIA World Congress of Architecture Torino 2008. La pianificazione, il processo, l’architettura. La trasmissione della conoscenza come funzione etica e principio di valorizzazione; La tutela del patrimonio industriale nel contesto internazionale; I cambiamenti della città. Nuovi approcci alla valorizzazione del patrimonio industriale; Memoria industriale, identità urbana e la progettazione del patrimonio post-industriale; La "rete della conoscenza" per l'educazione e la diffusione della cultura del patrimonio industriale; Una valutazione di 25 anni di de-industrializzazione e riuso, con attenzione alla parte nord della città di Torino La descrizione di casi internazionali e delle migliori prassi; Il cambiamento della città tra tradizione e innovazione; I vincoli di conservazione del patrimonio e reale pressione del mercato immobiliare. Introduction to Main Session “Transmitting Industrial City”, in XXIII UIA World Congress of Architecture Torino 2008. The planning, process, architecture. Transmitting knowledge as a ethics function and a principle of valorization; Industrial heritage protection in the international context; The changes of the city. New approaches to the enhancement of industrial heritage Industrial memory, urban identity and design of the post-industrial heritage The “knowledge network“ for the education and the dissemination of industrial heritage culture An assessment of 25 years of de-industrialization and re-use, focusing on the northern part of the city of Turin; The description of international cases and best practices; The city change between tradition and innovation; Heritage conservation constraints and real estate market pressure

Transmitting the industrial city / Trasmettere la città industriale

Introduzione alla Main Session "Trasmettere città industriale", nel XXIII UIA World Congress of Architecture Torino 2008. La pianificazione, il processo, l'architettura. La trasmissione della conoscenza come funzione etica e principio di valorizzazione; La tutela del patrimonio industriale nel contesto internazionale; I cambiamenti della città. Nuovi approcci alla valorizzazione del patrimonio industriale; Memoria industriale, identità urbana e la progettazione del patrimonio post-industriale; La "rete della conoscenza" per l'educazione e la diffusione della cultura del patrimonio industriale; Una valutazione di 25 anni di de-industrializzazione e riuso, con attenzione alla parte nord della città di Torino La descrizione di casi internazionali e delle migliori prassi; Il cambiamento della città tra tradizione e innovazione; I vincoli di conservazione del patrimonio e reale pressione del mercato immobiliare. Introduction to Main Session "Transmitting Industrial City", in XXIII UIA World Congress of Architecture Torino 2008. The planning, process, architecture. Transmitting knowledge as a ethics function and a principle of valorization; Industrial heritage protection in the international context; The changes of the city. New approaches to the enhancement of industrial heritage Industrial memory, urban identity and design of the post-industrial heritage The "knowledge network" for the education and the dissemination of industrial heritage culture An assessment of 25 years of de-industrialization and re-use, focusing on the northern part of the city of Turin; The description of international cases and best practices; The city change between tradition and innovation; Heritage conservation constraints and real estate market pressur

X chromosome inactivation does not necessarily determine the severity of the phenotype in Rett syndrome patients

Rett syndrome (RTT) is a severe neurological disorder usually caused by mutations in the MECP2 gene. Since the MECP2 gene is located on the X chromosome, X chromosome inactivation (XCI) could play a role in the wide range of phenotypic variation of RTT patients; however, classical methylation-based protocols to evaluate XCI could not determine whether the preferentially inactivated X chromosome carried the mutant or the wild-type allele. Therefore, we developed an allele-specific methylation-based assay to evaluate methylation at the loci of several recurrent MECP2 mutations. We analyzed the XCI patterns in the blood of 174 RTT patients, but we did not find a clear correlation between XCI and the clinical presentation. We also compared XCI in blood and brain cortex samples of two patients and found differences between XCI patterns in these tissues. However, RTT mainly being a neurological disease complicates the establishment of a correlation between the XCI in blood and the clinical presentation of the patients. Furthermore, we analyzed MECP2 transcript levels and found differences from the expected levels according to XCI. Many factors other than XCI could affect the RTT phenotype, which in combination could influence the clinical presentation of RTT patients to a greater extent than slight variations in the XCI pattern

Phenotype and genotype in Nicolaides-Baraitser syndrome

Nicolaides-Baraitser syndrome (NCBRS) is an intellectual disability (ID)/multiple congenital anomalies syndrome caused by non-truncating mutations in the ATPase region of SMARCA2, which codes for one of the two alternative catalytic subunits of the BAF chromatin remodeling complex. We analyzed 61 molecularly confirmed cases, including all previously reported patients (n = 47) and 14 additional unpublished individuals. NCBRS is clinically and genetically homogeneous. The cardinal features (ID, short stature, microcephaly, typical face, sparse hair, brachydactyly, prominent interphalangeal joints, behavioral problems and seizures), are almost universally present. There is variability however, as ID can range from severe to mild, and sparse hair may be present only in certain age groups. There may be a correlation between the severity of the ID and presence of seizures, absent speech, short stature and microcephaly. SMARCA2 mutations causing NCBRS are likely to act through a dominant-negative effect. There may be some genotype-phenotype correlations (mutations at domain VI with severe ID and seizures; mutations affecting residues Pro883, Leu946, and Ala1201 with mild phenotypes) but numbers are still too small to draw definitive conclusions

Phenotype and genotype in Nicolaides-Baraitser syndrome

Nicolaides-Baraitser syndrome (NCBRS) is an intellectual disability (ID)/multiple congenital anomalies syndrome caused by non-truncating mutations in the ATPase region of SMARCA2, which codes for one of the two alternative catalytic subunits of the BAF chromatin remodeling complex. We analyzed 61 molecularly confirmed cases, including all previously reported patients (n = 47) and 14 additional unpublished individuals. NCBRS is clinically and genetically homogeneous. The cardinal features (ID, short stature, microcephaly, typical face, sparse hair, brachydactyly, prominent interphalangeal joints, behavioral problems and seizures), are almost universally present. There is variability however, as ID can range from severe to mild, and sparse hair may be present only in certain age groups. There may be a correlation between the severity of the ID and presence of seizures, absent speech, short stature and microcephaly. SMARCA2 mutations causing NCBRS are likely to act through a dominant-negative effect. There may be some genotype-phenotype correlations (mutations at domain VI with severe ID and seizures; mutations affecting residues Pro883, Leu946, and Ala1201 with mild phenotypes) but numbers are still too small to draw definitive conclusions