1,426 research outputs found
Adiabatic motion of a neutral spinning particle in an inhomogeneous magnetic field
The motion of a neutral particle with a magnetic moment in an inhomogeneous magnetic field is considered. This situation, occurring, for example, in a Stern-Gerlach experiment, is investigated from classical and semiclassical points of view. It is assumed that the magnetic field is strong or slowly varying in space, i.e., that adiabatic conditions hold. To the classical model, a systematic Lie-transform perturbation technique is applied up to second order in the adiabatic-expansion parameter. The averaged classical Hamiltonian contains not only terms representing fictitious electric and magnetic fields but also an additional velocity-dependent potential. The Hamiltonian of the quantum-mechanical system is diagonalized by means of a systematic WKB analysis for coupled wave equations up to second order in the adiabaticity parameter, which is coupled to Planckās constant. An exact term-by-term correspondence with the averaged classical Hamiltonian is established, thus confirming the relevance of the additional velocity-dependent second-order contribution
DNA structural deformations in the interaction of the controller protein C.AhdI with its operator sequence
Controller proteins such as C.AhdI regulate the expression of bacterial restrictionāmodification genes, and ensure that methylation of the host DNA precedes restriction by delaying transcription of the endonuclease. The operator DNA sequence to which C.AhdI binds consists of two adjacent binding sites, OL and OR. Binding of C.AhdI to OL and to OLā+āOR has been investigated by circular permutation DNA-bending assays and by circular dichroism (CD) spectroscopy. CD indicates considerable distortion to the DNA when bound by C.AhdI. Binding to one or two sites to form dimeric and tetrameric complexes increases the CD signal at 278ānm by 40 and 80% respectively, showing identical local distortion at both sites. In contrast, DNA-bending assays gave similar bend angles for both dimeric and tetrameric complexes (47 and 38Ā°, respectively). The relative orientation of C.AhdI dimers in the tetrameric complex and the structural role of the conserved Py-A-T sequences found at the centre of C-protein-binding sites are discussed
DNA structural deformations in the interaction of the controller protein C.AhdI with its operator sequence
Controller proteins such as C.AhdI regulate the expression of bacterial restrictionāmodification genes, and ensure that methylation of the host DNA precedes restriction by delaying transcription of the endonuclease. The operator DNA sequence to which C.AhdI binds consists of two adjacent binding sites, OL and OR. Binding of C.AhdI to OL and to OLā+āOR has been investigated by circular permutation DNA-bending assays and by circular dichroism (CD) spectroscopy. CD indicates considerable distortion to the DNA when bound by C.AhdI. Binding to one or two sites to form dimeric and tetrameric complexes increases the CD signal at 278ānm by 40 and 80% respectively, showing identical local distortion at both sites. In contrast, DNA-bending assays gave similar bend angles for both dimeric and tetrameric complexes (47 and 38Ā°, respectively). The relative orientation of C.AhdI dimers in the tetrameric complex and the structural role of the conserved Py-A-T sequences found at the centre of C-protein-binding sites are discussed
High Resilience and Fast Acclimation Processes Allow the Antarctic Moss Bryum argenteum to Increase Its Carbon Gain in Warmer Growing Conditions
SIMPLE SUMMARY: Temperatures are increasing globally, but polar regions (including Antarctica) are warming much faster than the rest of the globe. Increased temperatures in Antarctica can impact the distribution and performance of plants, the majority of which on this continent are mosses. This study aims to investigate whether Bryum argenteum var. muticum, a moss species found in Antarctica, is capable of acclimation (adjustment of its physiology, specifically photosynthesis and respiration) to increased temperatures. We used short-term warming experiments that mimicked heatwaves and compared them to seasonal rates of photosynthesis and respiration in order to better understand how resilient this important moss species is to climate change. We found that this moss can acclimate very quickly (within 7 days) by increasing its photosynthesis (carbon gain). This shows that B. argenteum is highly resilient, and it may potentially benefit from short- and long-term climatic changes. ABSTRACT: Climate warming in Antarctica involves major shifts in plant distribution and productivity. This study aims to unravel the plasticity and acclimation potential of Bryum argenteum var. muticum, a cosmopolitan moss species found in Antarctica. By comparing short-term, closed-top chamber warming experiments which mimic heatwaves, with in situ seasonal physiological rates from Cape Hallett, Northern Victoria Land, we provide insights into the general inherent resilience of this important Antarctic moss and into its adaptability to longer-term threats and stressors associated with climate change. Our findings show that B. argenteum can thermally acclimate to mitigate the effects of increased temperature under both seasonal changes and short-term pulse warming events. Following pulse warming, this species dramatically increased its carbon uptake, measured as net photosynthesis, while reductions in carbon losses, measured as dark respiration, were not observed. Rapid growth of new shoots may have confounded the effects on respiration. These results demonstrate the high physiological plasticity of this species, with acclimation occurring within only 7 days. We show that this Antarctic moss species appears to have a high level of resilience and that fast acclimation processes allow it to potentially benefit from both short-term and long-term climatic changes
Decay Rate of Triaxially-Deformed Proton Emitters
The decay rate of a triaxially-deformed proton emitter is calculated in a
particle-rotor model, which is based on a deformed Woods-Saxon potential and
includes a deformed spin-orbit interaction. The wave function of the
ground state of the deformed proton emitter Ho is obtained
in the adiabatic limit, and a Green's function technique is used to calculate
the decay rate and branching ratio to the first excited 2 state of the
daughter nucleus. Only for values of the triaxial angle
is good agreement obtained for both the total decay rate and the 2
branching ratio.Comment: 19 pages, 4 figure
Global Superdiffusion of Weak Chaos
A class of kicked rotors is introduced, exhibiting accelerator-mode islands
(AIs) and {\em global} superdiffusion for {\em arbitrarily weak} chaos. The
corresponding standard maps are shown to be exactly related to generalized web
maps taken modulo an ``oblique cylinder''. Then, in a case that the web-map
orbit structure is periodic in the phase plane, the AIs are essentially {\em
normal} web islands folded back into the cylinder. As a consequence, chaotic
orbits sticking around the AI boundary are accelerated {\em only} when they
traverse tiny {\em ``acceleration spots''}. This leads to chaotic flights
having a quasiregular {\em steplike} structure. The global weak-chaos
superdiffusion is thus basically different in nature from the strong-chaos one
in the usual standard and web maps.Comment: REVTEX, 4 Figures: fig1.jpg, fig2.ps, fig3.ps, fig4.p
Phase transition in the collisionless regime for wave-particle interaction
Gibbs statistical mechanics is derived for the Hamiltonian system coupling
self-consistently a wave to N particles. This identifies Landau damping with a
regime where a second order phase transition occurs. For nonequilibrium initial
data with warm particles, a critical initial wave intensity is found: above it,
thermodynamics predicts a finite wave amplitude in the limit of infinite N;
below it, the equilibrium amplitude vanishes. Simulations support these
predictions providing new insight on the long-time nonlinear fate of the wave
due to Landau damping in plasmas.Comment: 12 pages (RevTeX), 2 figures (PostScript
Epidemiology of Staphylococcus aureus infections in patients admitted to freestanding pediatric hospitals, 2009-2016
Diabetes Mellitus in HIV-Infected Patients Receiving Antiretroviral Therapy
Background. There is little in the literature on HIV and diabetes mellitus (DM) in sub-Saharan Africa.
Objective. To assess the characteristics of HIV and DM in patients receiving antiretroviral therapy (ART) in Botswana.
Methods. A retrospective case-control study was conducted at 4 sites. Each HIV-infected patient with DM (n=48) was matched with 2 HIV-infected controls (n=108) by age (Ā±2 years) and sex. Primary analysis was conditional logistic regression to estimate univariate odds and 95% confidence intervals (CIs) for each characteristic.
Results. There was no significant association between co-morbid diseases, tuberculosis, hypertension or cancer and risk of diabetes. DM patients were more likely to have higher pre-ART weight (odds ratio (OR) 1.09; 95% CI 1.04 - 1.14). HIV-infected adults \u3e70 kg were significantly more likely to have DM (OR 12.30; 95% CI 1.40 - 107.98). Participants receiving efavirenz (OR 4.58; 95% CI 1.44 - 14.57) or protease inhibitor therapy (OR 20.7; 95% CI 1.79 - 240.02) were more likely to have DM. Neither mean pre-ART CD4 cell count (OR 1.0; 95% CI 0.99 - 1.01) nor pre-ART viral load \u3e100 000 copies/ml (OR 0.71; 95% CI 0.21 - 2.43) were associated with a significant risk of diabetes.
Conclusions. These findings suggest a complex interrelation among traditional host factors and treatment-related metabolic changes in the pathogenesis of DM inpatients receiving ART. Notably, pre-ART weight, particularly if \u3e70 kg, is associated with the diagnosis of diabetes in HIV-infected patients in Botswana
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