Evaluation of therapeutic drug protocol used for control of pain after dental extractions / Avaliação do protocolo terapêutico medicamentoso utilizado para o controle da dor após exodontias

Pain control after surgery is one of the factors concern of surgical specialties. Aim of this study is to evaluate and compare the efficacy of nimesulide 100 mg and dipyrone monohydrate 500 mg used after extractions performed by a maxillofacial surgery UFPI services in order to support the drug choice appropriately, prioritizing the analgesic effect needed to patients undergoing interventions. Forty patients underwent extractions in the clinic of the UFPI, in the Health Center Poty Velho and Emergency Hospital of Promorar. Patients were divided into groups: undergoing intervention with and without ostectomy. Dipyrone monohydrate 500 mg or nimesulide 100 mg produced by compounding pharmacy, were prescribed for patients randomly, featuring a blind study. The intensity of pain after the extraction was assessed by patients using a visual analogue scale, in a postoperative period of 72 hours at 24 hour intervals. There was no statistical variation between the analgesics studied during the 3 days postoperatively evaluated, considering the presence or absence of ostectomy as a modifier of the search. Analgesia effect of nimesulide was similar to dipyrone according to the present study

Analysis of self-etch adhesives behavior in class I composite restorations with different treatment of enamel margins and light-activation sources/ Análise do comportamento de adesivos autocondicionantes em restaurações de resina composta classe I com diferentes tratamentos das margens de esmalte e fontes de ativação de luz

Objective: To evaluate the microtensile bond strength (MTBS), knoop microhardness (KHN) and gap formation of class I restorations restored with self-etching adhesives and resin composites light-activated by either halogen or LED light curing units. Materials and Methods: Class I cavities were prepared in one hundred and forty-four human third molars. Three self-etching adhesives (Clearfil S3 Bond - S3, Clearfil Protect Bond – ProtectB and One-Up Bond F Plus - OneUp) were applied to the cavities, which had the enamel margins either etched with 35% phosphoric acid or left unecthed. The cavities were incrementally restored with TPH3 restorative composite, which was light-activated using Light Emitted by Diode (Hadii-Cal) or Halogen Lamp (Optilux 501). Epoxy resin replicas were obtained from the restored teeth, which were then submitted to thermal cycling. Afterwards, new replicas were obtained and the gaps at the resin composite/enamel margin interface were analyzed by Scanning Electronic Microscopy. Half sample was randomly tested for microtensile bond strength test (n=6) while the other half had the composite tested for KHN (n=6). Results: The etched enamel contributed to avoid gap formation only when OneUp adhesive system was used. No significant difference in MTBS values was found among groups. For KHN analysis, all restorations light-activated with LED showed higher KHN values than those light-activated with halogen lamps. In addition, the resin composites used to restore cavities with acid etched enamel margins showed higher KHN means than those used in cavities having unteched enamel margins. Conclusion: The resin composite bonded to cavities with S3 showed the lowest KHN values at the intermediate and bottom. ProtectB showed no significant differences for the different surface depths

Effects of residual contamination on mechanical properties and real-time conversion of etch-and-rinse adhesive / Efeitos da contaminação residual nas propriedades mecânicas e na cinética de conversão de adesivos convencionais

Introduction: An ideal hybrid layer should have water and solvents completely replaced by resin monomers, thus creating an interdiffusion zone with collagen and resin, and guaranteeing resistance and adequate mechanical properties to resist the challenges incurred in restoration. Objective: To evaluate the influence of residual contamination by different concentrations of water, ethanol and chlorexidine on mechanical properties and conversion of two etch-and-rinse adhesives. Method: Bar specimens of a model adhesive (M1) and a commercial Scotchbond MP adhesive (SBMP) were prepared and submitted to flexural strength (FS), elastic modulus (E), conversion degree (DC) and the kinetics of cure (K) evaluation. The real-time polymerization (RP) was monitored for 120 seconds. The data were statistically analyzed by two-way ANOVA and Tukey ?s test (?=0.05). Results: All solutions showed a decrease in FS and E values. For M1 adhesive, this decrease could be noted with increase of all dilutions tested. A decrease in DC values also was noted as dilutions increased, independent of solution tested. For SBMP adhesive, the mechanical properties were affected more by water and chlorexidine solutions and, it was noted an increase in DC with the increase of solution, especially for ethanol. For K test, adding water to adhesives, a progressive decrease could be noted on graphics. Conclusions: So a reduction in mechanical properties of adhesive solutions could be noted when extreme amounts of residual solutions. Nevertheless, at lowest concentrations, ethanol and chlorexidine seems not interfere on K and RP of adhesives. 

Effect of high-fluoride dentifrice on root dentine and bacterial composition in a multispecies biofilm model

The present study evaluated the effect of high-fluoride dentifrice on dentine demineralization and bacterial composition in a multispecies biofilm model in vitro. A seven-organism bacterial consortium was grown on bovine dentine discs in a high-throughput active attachment model. The biofilms were submitted twice per day to the following dentifrices treatments: 5,000 ppm F, 1,100 ppm F, with placebo as a negative control. After 5 days of biofilm growth, dentine samples were assessed by transversal microradiography, the biofilm was collected for bacterial counts and the pH of the media was determined. Lower integrated mineral loss values were observed when 5,000 ppm F-treatment was used compared to the other treatments. Overall microbiological counts decreased with increasing F-concentration as well the pH of the media throughout the experiment. The 5,000 ppm F-treatment caused a shift in microbial composition and reduced dentine demineralization in the in-vitro experimental model