BIOMECHANICAL ANALYSIS OF ELEMENTARY BALLET JUMPS: INTEGRATION OF FORCE PLATE DATA AND EMG RECORDS

The purpose of this research was to analyze the electromyographic (EMG) activity, ground reaction force and muscular behavior (concentric,isometric or eccentric) of the lower limb during elementary ballet jumps: "saute" in first position; "saute" in fifth position; "saute en cou de pie". Three trials of each jump were performed by a experienced female Ballet dancer. Results pointed out the existence of a pre-activation effect before landing in almost all cases. They also showed the negative correlation of EMG on the agonistantagonist pair tibialis anterior and medial gastrocnemius and a positive correlation of the EMG activity of adductors and rectus femoris, between medial gastrocnemius and soleus, and between rectus femoris and the vertical ground reaction force. However, most of the parameters measured show great sensitivity to the technical execution making it impossible to generalize these findings

Double shunt technique for hybrid palliation of hypoplastic left heart syndrome: a case report

We report a technique to palliate hypoplastic left heart syndrome, with no PDA stenting, but with double polytetrafluoroethylene shunt from pulmonary artery to ascending and descending aorta by combined thoracotomies. A 30-day-old female was operated with this technique. Five months after first operation, the child was submitted to Norwood/Glenn operation. Good hemodinamic recovery and initial clinical evolution was observed. The child was extubated in 8th post operatory day and reentubated in the next day due to pulmonary infection. Despite antibiotic treatment, the child died after systemic infectious complications

Identification of hereditary cancer in the general population: development and validation of a screening questionnaire for obtaining the family history of cancer

One of the challenges for Latin American countries is to include in their healthcare systems technologies that can be applied to hereditary cancer detection and management. The aim of the study is to create and validate a questionnaire to identify individuals with possible risk for hereditary cancer predisposition syndromes (HCPS), using different strategies in a Cancer Prevention Service in Brazil. The primary screening questionnaire (PSQ) was developed to identify families at-risk for HCPS. The PSQ was validated using discrimination measures, and the reproducibility was estimated through kappa coefficient. Patients with at least one affirmative answer had the pedigree drawn using three alternative interview approaches: in-person, by telephone, or letter. Validation of these approaches was done. Kappa and intraclass correlation coefficients were used to analyze data’s reproducibility considering the presence of clinical criteria for HCPS. The PSQ was applied to a convenience sample of 20,000 women of which 3121 (15.6%) answered at least one affirmative question and 1938 had their pedigrees drawn. The PSQ showed sensitivity and specificity scores of 94.4% and 75%, respectively, and a kappa of 0.64. The strategies for pedigree drawing had reproducibility coefficients of 0.976 and 0.850 for the telephone and letter approaches, respectively. Pedigree analysis allowed us to identify 465 individuals (24.0%) fulfilling at least one clinical criterion for HCPS. The PSQ fulfills its function, allowing the identification of HCPS at-risk families. The use of alternative screening methods may reduce the number of excluded at-risk individuals/families who live in locations where oncogenetic services are not established.Research supported by Barretos Cancer Hospital. EIP has a grant from FAPESP (FAPESP, SP, Brazil, #2013/24633-2). N Campacci is supported by a PhD fellowship from FAPESP (FAPESP, SP, Brazil, #2015/02444-9).info:eu-repo/semantics/publishedVersio

Sustainable intensification using irrigation and N fertilization for pasture production in Tocantins, Brazil.

To verify the influence of irrigation in a pasture of Panicum maximum cv. Massai was carried out a field research testing rainfed and two irrigation depths (SO and 100% of evapotranspiration) and 300 kg ha-1 year-1 of N-urea, during one year at the periods Jun-Sep, Oct-Nov, Dec-Mar and Apr-May, in Tocantins state, Brazil

Sustainable intensification using irrigation and N fertilization for pasture production in Tocantins, Brazil.

Cattle raising is among the main Brazilian economic activities. Currently, there are 169 million hectares covered by tropical grasslands and 30% of this area is degraded. In the last 40 years, the area occupied by grasslands in Brazil increased only 17% while the meat production increased 114% and that fact was only possible due to national effort and investments on agricultural research, development and innovation. To verify the influence of irrigation in a pasture of Panicum maximum cv. Massai was carried out a field research testing rainfed and two irrigation depths (SO and 100% of evapotranspiration) and 300 kg ha-1 year-1 of N-urea, during one year at the periods Jun-Sep, Oct-Nov, Dec-Mar and Apr-May, in Tocantins state, Brazil. The parameters are one animal unit (AU) corresponding to 450 kg of liveweight, a daily dry matter intake of 11.25 kg. The accumulated dry matter (kg ha-1 day-1 ) obtained by the 100% depth was significantly higher than the others in almost all periods analyzed, and during Jun-Sep the treatment 50% depth showed no significant difference when compared to 100% depth suggesting seasonality probably related to low temperatures. The results revealed the potential to achieve a stocking rate of 6.44, 4.20 and 3.51 AU ha-1 year-1 with 100%, 50% depths and rainfed treatment, respectively. Despite promising results, further studies on physiology, phenology and economy must be done to confirm the feasibility of using irrigation for pasture production in Tocantins

GABRB1 Single Nucleotide Polymorphism Associated with Altered Brain Responses (but not Performance) during Measures of Impulsivity and Reward Sensitivity in Human Adolescents.

Variations in genes encoding several GABAA receptors have been associated with human drug and alcohol abuse. Among these, a number of human studies have suggested an association between GABRB1, the gene encoding GABAA receptor β1 subunits, with Alcohol dependence (AD), both on its own and comorbid with other substance dependence and psychiatric illnesses. In the present study, we hypothesized that the GABRB1 genetically-associated increased risk for developing alcoholism may be associated with impaired behavioral control and altered sensitivity to reward, as a consequence of altered brain function. Exploiting the IMAGEN database (Schumann et al., 2010), we explored in a human adolescent population whether possession of the minor (T) variant of the single nucleotide polymorphism (SNP) rs2044081 is associated with performance of tasks measuring aspects of impulsivity, and reward sensitivity that are implicated in drug and alcohol abuse. Allelic variation did not associate with altered performance in either a stop-signal task (SST), measuring one aspect of impulsivity, or a monetary incentive delay (MID) task assessing reward anticipation. However, increased functional magnetic resonance imaging (fMRI) blood-oxygen-level dependent (BOLD) response in the right hemisphere inferior frontal gyrus (IFG), left hemisphere caudate/insula and left hemisphere inferior temporal gyrus (ITG) during MID performance was higher in the minor (T) allelic group. In contrast, during SST performance, the BOLD response found in the right hemisphere supramarginal gyrus, right hemisphere lingual and left hemisphere inferior parietal gyrus indicated reduced responses in the minor genotype. We suggest that β1-containing GABAA receptors may play a role in excitability of brain regions important in controlling reward-related behavior, which may contribute to susceptibility to addictive behavior

Adaptation and validation of the Patient Expectations and Satisfaction with Prenatal Care instrument among Brazilian pregnant women

Objective: to adapt and validate the Patient Expectations and Satisfaction with Prenatal Care instrument for use in Brazil. It contains 41 items divided into two dimensions: expectations and satisfaction. The adapted version was submitted to analysis for stability, convergent construct validity, and internal consistency (Cronbach’s alpha) for distinct groups and dimensions. Method: 119 pregnant women receiving prenatal care were interviewed and 26 of these women answered the instrument twice (retest). Internal consistency was appropriate (Cronbach’s alpha ≥ 0.70); test-retest presented strong correlation (r=0.82; p<0.001) for the domain expectations and moderate correlation (r=0.66; p<0.001) for the satisfaction domain. The analysis confirmed that the instrument’s adapted version is valid in the studied group. Results: there is strong evidence for the validity and reliability of the instrument’s adaptation. Conclusion: the instrument needs to be tested in groups of pregnant women with different social characteristics.CAPESCAPE