The sciences in America, circa 1880

For many years American science in the late 19th century was regarded as an intellectual backwater. This view derived from the assumption that the health of American science at the time was equivalent to the condition of pure science, especially pure physics. However, a closer look reveals that there was considerable vitality in American scientific research, especially in the earth and life sciences. This vitality is explainable in part by the natural scientific resources of the American continent but also in part by the energy given science from religious impulses, social reformism, and practicality. Furthermore, contrary to recent assumptions, the federal government was a significant patron of American science. The portrait of American science circa 1880 advanced in this article suggests that the nation's scientific enterprise was characterized by pluralism of institutional support and motive and that such pluralism has historically been the normal mode

Onsite Wastewater Treatment: Implementation of a region-wide Integrated Risk Framework

Onsite wastewater treatment systems are becoming more widely accepted as long term wastewater treatment systems in areas not serviced by centralised sewerage systems. However, the current means of assessing site and soil conditions to provide adequate treatment and dispersal of domestic wastewater has been a major drawback in achieving specific performance outcomes. In Australia, it is the responsibility of local governments to assess and approve the use of onsite systems, and appreciable variations in standards and codes exist between different jurisdictions. The main aim of this research was to develop a scientific framework for assessing onsite systems, based on risk assessment and management principles thereby allowing more appropriate integration across local government boundaries. A case study illustrating the implementation of the risk framework is also presented

β-Catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state

AbstractDifferentiation is the process by which tissues/organs take on their final, physiologically functional form. This process is mediated in part by the silencing of embryonic genes and the activation of terminal, differentiation gene products. Mammalian kidney development is initiated when the Wolffian duct branches and invades the overlying metanephric mesenchyme. The newly formed epithelial bud, known as the ureteric bud, will continue to branch ultimately differentiating into the collecting duct system and ureter. Here, we show that Hoxb7-Cre mediated removal of β-catenin from the mouse Wolffian duct epithelium leads to the premature expression of gene products normally associated with the differentiated kidney collecting duct system including the water channel protein, Aquaporin-3 and the tight junction protein isoform, ZO-1α+. Mutant cells fail to maintain expression of some genes associated with embryonic development, including several mediators of branching morphogenesis, which subsequently leads to kidney aplasia or hypoplasia. Reciprocally, expression of a stabilized form of β-catenin appears to block differentiation of the collecting ducts. All of these defects occur in the absence of any effects on the adherens junctions. These data indicate a role for β-catenin in maintaining cells of the Wolffian ducts and the duct derived ureteric bud/collecting duct system in an undifferentiated or precursor state

Imaging the Dipole-Dipole Energy Exchange Between Ultracold Rubidium Rydberg Atoms

The long-range, anisotropic nature of the interaction among atoms in an ultracold dipolar gas leads to a rich array of possibilities for studying many-body physics. In this work, an ultracold gas of highly excited atoms is used to study energy transport due to the long-range dipole-dipole interaction. A technique is developed to measure both the internal energy states of the interacting Rydberg atoms and their positions in space. This technique is demonstrated by observing energy exchange between two spatially separated groups of Rydberg atoms excited to two different internal states. Simulations confirm the general features of the energy transport in this system and highlight subtleties associated with the homogeneity of the electric field used in this experiment

Time Dependence of Few-Body Forster Interactions Among Ultracold Rydberg Atoms

Rubidium Rydberg atoms in either |mj| sublevel of the 36p3/2 state can exchange energy via Stark-tuned Förster resonances, including two-, three-, and four-body dipole-dipole interactions. Three-body interactions of this type were first reported and categorized by Faoro et al. [Nat. Commun. 6, 8173 (2015)] and their Borromean nature was confirmed by Tretyakov et al. [Phys. Rev. Lett. 119, 173402 (2017)]. We report the time dependence of the N-body Förster resonance N×36p3/2,|mj|=1/2→36s1/2+37s1/2+(N−2)×36p3/2,|mj|=3/2, for N=2, 3, and 4, by measuring the fraction of initially excited atoms that end up in the 37s1/2 state as a function of time. The essential features of these interactions are captured in an analytical model that includes only the many-body matrix elements and neighboring atom distribution. A more sophisticated simulation reveals the importance of beyond-nearest-neighbor interactions and of always-resonant interactions

Dipole-Dipole Interaction Between Rubidium Rydberg Atoms

Ultracold Rydberg atoms in a static electric field can exchange energy via the dipole-dipole interaction. The Stark effect shifts the energy levels of the atoms which tunes the energy exchange into resonance at specific values of the electric field (F¨orster resonances). We excite rubidium atoms to Rydberg states by focusing either a 480 nm beam from a tunable dye laser or a pair of diode lasers into a magneto-optical trap. The trap lies at the center of a configuration of electrodes. We scan the electric field by controlling the voltage on the electrodes while measuring the fraction of atoms that interact. Dipole-dipole interaction spectra are presented for initially excited rubidium nd states for n = 31 to 46 and for four different pairs of initially excited rubidium ns states. We also present the dipole-dipole interaction spectra for individual rubidium 32d (j,mj ) fine structure levels that have been selectively excited. The data are compared to calculated spectra

CSO and CARMA Observations of L1157. II. Chemical Complexity in the Shocked Outflow

L1157, a molecular dark cloud with an embedded Class 0 protostar possessing a bipolar outflow, is an excellent source for studying shock chemistry, including grain-surface chemistry prior to shocks, and post-shock, gas-phase processing. The L1157-B1 and B2 positions experienced shocks at an estimated ~2000 and 4000 years ago, respectively. Prior to these shock events, temperatures were too low for most complex organic molecules to undergo thermal desorption. Thus, the shocks should have liberated these molecules from the ice grain-surfaces en masse, evidenced by prior observations of SiO and multiple grain mantle species commonly associated with shocks. Grain species, such as OCS, CH3OH, and HNCO, all peak at different positions relative to species that are preferably formed in higher velocity shocks or repeatedly-shocked material, such as SiO and HCN. Here, we present high spatial resolution (~3") maps of CH3OH, HNCO, HCN, and HCO+ in the southern portion of the outflow containing B1 and B2, as observed with CARMA. The HNCO maps are the first interferometric observations of this species in L1157. The maps show distinct differences in the chemistry within the various shocked regions in L1157B. This is further supported through constraints of the molecular abundances using the non-LTE code RADEX (Van der Tak et al. 2007). We find the east/west chemical differentiation in C2 may be explained by the contrast of the shock's interaction with either cold, pristine material or warm, previously-shocked gas, as seen in enhanced HCN abundances. In addition, the enhancement of the HNCO abundance toward the the older shock, B2, suggests the importance of high-temperature O-chemistry in shocked regions.Comment: Accepted for publication in the Astrophysical Journa

Metric-affine f(R) theories of gravity

General Relativity assumes that spacetime is fully described by the metric alone. An alternative is the so called Palatini formalism where the metric and the connections are taken as independent quantities. The metric-affine theory of gravity has attracted considerable attention recently, since it was shown that within this framework some cosmological models, based on some generalized gravitational actions, can account for the current accelerated expansion of the universe. However we think that metric-affine gravity deserves much more attention than that related to cosmological applications and so we consider here metric-affine gravity theories in which the gravitational action is a general function of the scalar curvature while the matter action is allowed to depend also on the connection which is not {\em a priori} symmetric. This general treatment will allow us to address several open issues such as: the relation between metric-affine $f(R)$ gravity and General Relativity (in vacuum as well as in the presence of matter), the implications of the dependence (or independence) of the matter action on the connections, the origin and role of torsion and the viability of the minimal-coupling principle.Comment: typos corrected, replaced to match published versio