Transscleral Optical Phase Imaging of the Human Retina.

In-vivo observation of the human retina at the cellular level is crucial to detect the first signs of retinal diseases and properly treat them. Despite the phenomenal advances in adaptive optics (AO) systems, clinical imaging of many retinal cells is still elusive due to the low signal-to-noise ratio induced by transpupillary illumination. We present a transscleral optical phase imaging (TOPI) method, which relies on high-angle oblique illumination of the retina, combined with AO, to enhance cell contrast. Examination of eleven healthy volunteer eyes, without pupil dilation, shows the ability of this method to produce in-vivo images of retinal cells, from the retinal pigment epithelium to the nerve fibre layer. This method also allows the generation of high-resolution label-free ex-vivo phase images of flat-mounted retinas. The 4.4°x 4.4° field-of-view in-vivo images are recorded in less than 10 seconds, opening new avenues in the exploration of healthy and diseased retinas

Democracy by Design: Perspectives for Digitally Assisted, Participatory Upgrades of Society

The technological revolution, particularly the availability of more data and more powerful computational tools, has led to the emergence of a new scientific field called “Computational Diplomacy”. Our work tries to define its scope and focuses on a popular subarea of it, namely “Digital Democracy”. In recent years, there has been a surge of interest in using digital technologies to promote more participatory forms of democracy. While there are numerous potential benefits to using digital tools to enhance democracy, significant challenges must be addressed. It is essential to ensure that digital technologies are used in an accessible, equitable, and fair manner rather than reinforcing existing power imbalances. This paper investigates how digital tools can be used to help design more democratic societies by investigating three key research areas: (1) the role of digital technologies for facilitating civic engagement in collective decision-making; (2) the use of digital tools to improve transparency and accountability in governance; and (3) the potential for digital technologies to enable the formation of more inclusive and representative democracies. We argue that more research on how digital technologies can be used to support democracy upgrade is needed. Along these lines, we lay out a research agenda for the future

Review on recent groundbreaking experiments on quantum communication with orthogonal states

In recent years Quantum Key Distribution (QKD) has emerged as the most paradigmatic example of Quantum technology allowing the realization of intrinsically secure communication links over hundreds of kilometres. Beyond its commercial interest QKD also has high conceptual relevance in the study of quantum information theory and the foundations of quantum mechanics. In particular, the discussion on the minimal resources needed in order to obtain absolutely secure quantum communication is yet to be concluded. Here we present an overview on our last experimental results concerning two novel quantum cryptographic schemes which do not require some of the most widely accepted conditions for realizing QKD. The first is Goldenberg-Vaidman protocol, in which even if only orthogonal states (that in general can be cloned without altering the state) are used, any eavesdropping attempt is detectable. The second is N09 protocol which, being based on the quantum counterfactual effect, does not even require any actual photon transmission in the quantum channel between the parties for the communication