THE IMPLICATIONS OF GROSS FIXED CAPITAL AND UNEMPLOYMENT RATE GENERAL GOVERNMENT DEFICIT. EMPIRICAL STUDY AT THE EUROPEAN LEVEL

In this paper we evaluate the influence of the modification of public investment level and unemployment rate on the general government deficit at the European Union level. We create a regression model that shows that a sustained and increased investment policy and the reduction of unemployment rate have a favorable effect on the objective of minimizing the budget deficit. In the last years European Union’s countries had to face a difficult problem concerning fiscal policy. They have to make public investments to stimulate economic growth and in the same time they have to meet the convergence criteria’s of public deficit. On the other hand, EU has to deal with a higher rate of unemployment. Through our model we try to see how European Union countries should implement their political strategies on unemployment and investment with the main objective of reducing the general government deficit.general government deficit, gross fixed capital, unemployment rate, correlation, regression

The effect of discretionary accruals on firm growth. Empirical evidence for SMEs from emerging Europe

The aim of the paper is to assess the effect of discretionary accruals on firm growth while controlling for firm characteristics and macroeconomic environment. Employing a large sample of 1.105 young and high-growth firms (gazelles) from 15 emerging European countries over the period 2006–2014, it has been found that the discretionary accruals negatively influence firm growth. The empirical results suggest that discretionary accruals are used as earnings management tools and this practice is more used over the high-growth period (2006–2009), with negative effects on future performance. Furthermore, the results of the quantile regression employed in the whole period suggest that the earnings management practices have a negative effect on firm growth. The results prove to be robust for different estimation approaches and different sub-samples of gazelles. The findings provide empirical evidence for the need for more detailed information provided by firms on the origin of the accruals, as well as for the use in the performance analysis of some indicators that eliminate the influence of accruals, such as cash flow based ratios

Comparative evaluation of three testing methods for detection of mediated resistance MBL in pseudomonas aeruginosa isolates

Metallo – β – lactamase (MBL) producing Pseudomonas aeruginosa have been reported to be important cause of nosocomial infections. The appearance of MBL genes and their spread among bacterial pathogens is a matter of concern with regard to the future of antimicrobial therapy. The present study was undertaken to determine which method is better to use in laboratory for detecting MBL producing P. aeruginosa. A total of 182isolates of P. aeruginosa from human and animals, 125 from human and 57 from animals, (burns, pus, urine, blood cultures, etc.), collected between 2013 and 2015 were subjected to susceptibility testing against various antibiotics by disc diffusion test according to Clinical and Laboratory Standards Institute (CLSI) guidelines 2015. Imipenem resistant isolates were selected for the detection of MBL production by E-test strips for screening MBL, double disc method (IPM and IPM+EDTA) and EDTA solution application on microcaps IPM. The positive results have been based on inhibition zone around imipenem discs impregnated with EDTA as compared to those without EDTA confirmed MBL production and for E-test strips the strains were positive those that have developed around area with EDTA solution. The double disc method (IPM and IPM+EDTA is most effective way to use in laboratory to determine early producer P. aeruginosa MBL, having 2 advantage: first is the low cost for materials (MH agar and microcaps) and the technique is very easy to be applied

The Prevalence of Esbl-Producing Strains of E.coli, Isolated from Calves with Colibacilosis - Preliminary Remarks

The animals producing food have become an increasing reservoir of extended spectrum beta-lactamase producing Enterobacteriaceae. The calves and cows are exposed to a greater quantity of antibiotics, but the data concerning the prevalence of ESBL-producing Enterobacteriaceae are not enough, in comparison with other species of animals used for human consumption, such as birds (Hordijk et al., 2013).The aim of this study was to determine the prevalence of ESBL-producing E. coli involved in some episodes of colibacilosis in calves. Faeces samples were collected from 33 calves with the age ranging between 1-2 weeks and that presented clinical signs of colibacilosis. The samples were collected in a sterile medium for the taxonomic isolation and identification of the etiological agent involved, the ESBL screening being conducted subsequently using the ESBL Agar Oxoid Brilliance chromogenic medium. The phenotypic confirmation of the ESBL-producing strains was conducted in accordance with the CLSI (2014) standard through the combined disc method. Following the tests conducted, out of the 33 strains of isolated E. coli, 9 (27, 27%) were phenotypically confirmed as being ESBL strains.The studies that were previously conducted on the dairy farms have pointed out that the young calves rapidly acquire bacterial strains resistant to antibiotics that are often ESBL strains (Hordijk et al., 2013). The prevalence obtained by us, as well as an insufficient quantity of information concerning the antimicrobial resistance on this segment of species of animals used for the human consumption, support conducting a more thorough study, as well as the identification of ESBL resistance genes, but also of the plasmids that encode the transmission of these genes

Characterisation of Extended β-Lactamases and Plasmid Mediated Quinolones Resistancein Escherichia Coli from Shelter Dogs

The aim of this study was to determine the prevalence of β-lactamase (TEM, SHV, OXA), extended-spectrum β-lactamase (ESBL) and genes encoding plasmid mediated resistance to quinolones (PMQR) in extended spectrum cephalosporin (ESC)-resistant Escherichia coli isolated from dog faeces from two shelters in the North-East of Romania. Eighty-eight faecal samples from healthy dogs were analysed by cultivation on Brilliance ESBL medium (Oxoid, UK), followed by phenotipic ESBL screening using combination disc test (CDT). Identification of the E. coli strains was performed by uidA/uspA gene PCR. Susceptibility testing was performed on Mueller-Hinton Agar, with β-lactam and non-β-lactam agents. Identification of β-lactamase genes (blaCTX-M, blaTEM, blaSHV, blaOXA) and PMQR genes (qnrA, qnrB and qnrS) was performed by PCR as previously described. Twenty eight ESC-resistant E. coli (31.81%) were obtained and (n=21/28, 75%) of these were confirmed as ESBLs and showed resistance to cefpodoxime (n=21/28, 75%), amoxicillin/clavulanic acid (n=19/21; 90.48%), and enrofloxacin (n=8/21; 38.09%). Predominant ESBL types were CTX-M-1 (n=15/17, 88.24%) and CTX-M-9 (n=2/17, 11.76%) enzymes. TEM and SHV enzymes were identified in 17.86% and 14.29% of the ESC-resistant isolates, whilst some isolates (n=4) carried only blaTEM and blaSHV. The prevalence of PMQR genes was 28.57% of the 28 ESC resistant isolates, consisting of qnrS (62.5%) and qnrB (37.5%). These findings indicate a high prevalence of ESBLs and PMQR associated resistance E. coli in the normal faecal microbiota of dogs from shelters, which carries the risk for dissemination of these resistance genes to other animals, human or the environment