236 research outputs found

    Downer Women 1851 - 2001 : celebrating the 150th anniversary Milwaukee Normal Institute and High School

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    https://lux.lawrence.edu/mdc_writtenhistories/1004/thumbnail.jp

    Phonological Parameters of Indigenous and ASL Country Name-Signs

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    This investigation was guided by the following research questions: What are the American Sign Language (ASL) and indigenous signs for each country in the world? What phonological features do they exhibit? Are these features consistent with previous research on ASL? The research presented in this article is the result of a project that provides a comprehensive online compilation of country-name signs. A website was created to display both written descriptions and videos of the signs, and 180 countries with 314 total variations were identified, documented, recorded, coded and analyzed. A thorough literature review was conducted and an analysis of phonological parameters based on Battison (1978) was performed using pivot tables in Microsoft Excel. Findings include: (a) the distinction between the 1 and g/q handshape in previous literature; (b) 100% of the applicable signs analyzed satisfied the symmetry condition; and (c) indigenous signs adopted into ASL are frequently altered to contain two iterations instead of just one beat. An in-depth discussion of the implications of language contact, globalization, technology and practical application for interpreters is included

    The Consolidation: Effects of the Consolidation of Milwaukee-Downer and Lawrence Colleges and Affects on Milwaukee-Downer Alumnae, Volume 2, Number 2

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    Effects of the Consolidation and Affects on Milwaukee-Downer Alumnae uses interviews and story telling to extend the perspective of alumnae through time. It updates the Downer history with Effects of the Consolidation on five sectors of Alumnae, each given a chapter, as listed in the Index.https://lux.lawrence.edu/mdc_writtenhistories/1003/thumbnail.jp

    The Urban League of Oklahoma City, Oklahoma /

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    Selective Expression of Immune-Associated Surface Antigens by Keratinocytes in Irritant Contact Dermatitis

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    The expression of three immunoregulatory surface antigens by epidermal keratinocytes was studied in irritant contact dermatitis (lCD), in order to assess whether keratinocytes have a modulatory role in the pathogenesis of this disorder. Biopsies were taken from 48-h patch test reactions to six structurally unrelated irritants, and frozen sections immunolabeled with monoclonal antibodies to the major histocompatibility complex class II antigen, HLA-DR, intercellular adhesion molecule-i (ICAM-1), and the 88-Kd glycoprotein CD36 (OKM5), as well as to the CD3 (T cells) and CD11a (lymphocyte function associated antigen-1, LFA-1) antigens. We found that there was very limited expression of HLA- DR by keratinocytes, with no correlation between the extent of HLA-DR positivity and the degree of T cell infiltration into the epidermis and dermis, suggesting that interferon gamma may not be a significant mediator of lCD at 48h. In contrast, keratinocytes showed extensive upregulation of ICAM-1, with an excellent spatial association between ICAM-1 expression and LFA-1 positive leucocytes in the epidermis. This indicates that keratinocyte JCAM-1 induction is not restricted to diseases in which antigen presentation is pivotal, but that it has a generalized role in cutaneous inflammatory reactions, promoting the infiltration of leucocytes into the epidermis. Immunolabeling with OKM5 revealed that CD36 is present to a variable degree on keratinocytes in normal skin. Differential changes in the pattern of keratinocyte expression occurred between irritants, in a manner that suggested that the CD36 antigen does not act as an adhesion molecule in lCD, but rather that its expression is related to the proliferative state of the epidermis. The results of this study demonstrate that immune-associated antigens are selectively expressed on the surface of keratinocytes in 48-h ICD biopsies, implying that these cells play an important regulatory role in the development of the inflammatory response to irritant chemicals

    South America

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