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Excavating in the WanderstraĂen der Kultur. Piranesiâs Candalebra and the material Reception of Antiquity
Usually we do not think of Warburg as an archaeologist. He rather appears, carefully dressed, as the scholar in his studio, surrounded by the images he cut out for his collages. But his favourite metaphor to describe his lifeâs work was that of the excavator: to retrace, as he put it in one version, the vagaries of Nachleben as the unearthing of villages and towns of which only isolated road blocks and fading road numbers survived. In another version of the archaeological metaphor he described his study of the survival of pathos formulas as âpreliminary excavation reports about the first stages of the migration routes along which ancient gesture travelled from Athens to Rome, Florence and Nurembergâ.
These metaphors suggest something that until now has remained somewhat neglected in both reception and Nachleben studies: that not only images survive, but objects as well, and that they survive not just as the carriers of images, but as material objects as well. And whereas reception studies of images is by now a well-established and flourishing discipline, especially in the UK, the material reception of Antiquity is still an emerging field. Biographies of objects over long periods are now occasionally written, but the biographical model is a bit of a mixed blessing: it helps structure the narrative, but tends to favour a conception of an object as a unique individual, rather than a member of a class or type. Also, the metaphor of the life of an object gives the narrative a certain shape and drive that obscures all sorts of methodological issues
Introduction
This session is devoted to a reconsideration of the way disciplines are defined, and their boundaries established, with regard to early modern architecture in Italy and the ways its history is written. So why did Maarten Delbeke and I as session chairs decide to tackle this issue by inviting scholars who are specialists on Vitruvius, Jesuit architecture, or architectural thought at the court of Cosimo I? What, you may very well ask, is the relation between a paper on Jesuit historiography of ..
Conceptions de lâornement en quĂȘte de discours scientifique
Les trois livres Ă©tudiĂ©s ici offrent un nouvel Ă©clairage sur lâhistoire complexe de lâornement en Occident. LâĂ©tude de Clare Guest sur la comprĂ©hension de lâornement Ă la Renaissance est une tentative ambitieuse et trĂšs savante de retracer la prĂ©histoire des concepts avant lâĂ©mergence de lâesthĂ©tique kantienne. Guest remonte aux dĂ©buts de la pensĂ©e occidentale sur lâornement, dans lâAncien Testament, dans les pensĂ©es grecques platonicienne, aristotĂ©licienne et sophistique, et dans la scolastique, pour retrouver une conception de lâornement et de la beautĂ© qui ne soit pas dĂ©terminĂ©e Ă partir dâun concept relatif de la beautĂ©, et qui rĂ©sonne tout de mĂȘme avec lâidĂ©e grecque selon laquelle lâornement serait lâĂ©clat de la vĂ©ritĂ© et de la beautĂ©. Le livre de RĂ©mi Labrusse se penche quant Ă lui sur lâhistoire de lâornement aprĂšs le moment kantien. Il sâagit dâune Ă©tude tout aussi dense et trĂšs sophistiquĂ©e des tentatives du xixe siĂšcle pour repenser lâornement, sa conception et son histoire, face aux dĂ©fis posĂ©s par lâĂ©mergence dâune prise de conscience de la nature globale de lâart et de lâornementation humaine et des changements radicaux que la rĂ©volution industrielle imprime Ă la production artistique. Câest un nouveau dĂ©part fondamental. TournĂ© vers le xxe siĂšcle, le volume Histories of Ornament. From Global to Local, dirigĂ© par GĂŒlru Necipoglu et Alina Payne, remet en question le paradigme moderniste, ou plutĂŽt son rejet de lâornement, Ă partir de la rĂ©surgence de lâornementation de surface dans lâĆuvre dâarchitectes contemporains tels que Herzog & De Meuron ou Farshid Moussavi. Ces trois livres se distinguent par une remise en cause fondamentale des idĂ©es reçues sur lâornement conçu comme complĂ©ment de lâobjet quâil orne, et donc superflu, et montrent de diffĂ©rentes maniĂšres que la question de lâornement est au cĆur de lâart et de la culture matĂ©rielle humains.The three books under review here all throw important new light on the complex history of ornament in the West. Clare Guestâs study of the understanding of ornament in the Renaissance is an ambitious and highly learned attempt to recover the pre-history of concepts before the emergence of Kantian aesthetics. Guest goes back to the beginning of Western thought on ornament, in the Old Testament, in Greek Platonic, Aristotelian and Sophistic thought, and in Scholasticism, to retrieve a conception of ornament and beauty that is not predicated on a relational concept of beauty, and still resonates with the Greek idea that ornament is the splendor of truth and beauty. RĂ©mi Labrusseâs book looks at the history of ornament after the Kantian moment. It is an equally dense, highly sophisticated study of 19th-century attempts to rethink ornament, its design and history, in the face of the challenges posed by the emergence of an awareness of the global nature of human art and ornament-making, and the radical changes on artistic production imposed by the Industrial Revolution. It is a fundamental new departure. Moving to the 20th century, the volume Histories of Ornament. From Global to Local, edited by GĂŒlru Necipoglu and Alina Payne, questions the Modernist paradigm, or rather, rejection of ornament, inspired by the resurgence of surface ornament in the work of contemporary architects such as Herzog & De Meuron or Farshid Moussavi. All three books are distinguished by a fundamental questioning of received opinions about ornament as something added to the object it adorns, and therefore expendable, and show in different ways that the question of ornament lies at the heart of human art and material culture.Die drei hier untersuchten BĂŒcher werfen ein neues Licht auf die komplexe Geschichte des Ornaments in der westlichen Kultur. Clare Guests Studie ĂŒber das VerstĂ€ndnis des Ornaments in der Renaissance ist ein ehrgeiziger und gelehrter Versuch, die Vorgeschichte der Konzepte aus der Zeit vor Kants Ăsthetik nachzuzeichnen. Guest geht bis zu den AnfĂ€ngen des westlichen Ornamentgedankens zurĂŒck, wie er im Alten Testament, in den griechischen Quellen des platonischen, aristotelischen und sophistischen Denkens sowie in der Scholastik vorkommt. Hier verortet sie eine Auffassung von Ornament und Schönheit, die nicht von einem relativen Schönheitsbegriff bestimmt wird, aber dennoch mit der griechischen Idee einhergeht, dass das Ornament der Ausdruck von Wahrheit und Schönheit ist. Das Buch von RĂ©mi Labrusse befasst sich mit der Geschichte des Ornaments nach dem Kantschen Moment. Es handelt sich um eine ebenso dichte und ausgefeilte Studie ĂŒber die Versuche des 19. Jahrhunderts, das Ornament, seine Gestaltung und Geschichte angesichts der damaligen Herausforderungen neu zu ĂŒberdenken. Dies galt besonders im Blick auf das Aufkommen eines neuen Bewusstseins fĂŒr die globale Natur der Kunst und Ornamentierung und auf die radikalen VerĂ€nderungen, die die industrielle Revolution fĂŒr die kĂŒnstlerische Produktion mit sich brachte. Hierin findet man eine grundlegende Neuerung. Der von GĂŒlru Necipoglu und Alina Payne herausgegebene Band Histories of Ornament. From Global to Local beschĂ€ftigt sich hauptsĂ€chlich mit dem 20. Jahrhundert und stellt das Paradigma der Moderne, oder eher ihre Ablehnung des Ornaments in Frage, indem sich die Autoren dem Wiederaufleben der OberflĂ€chenornamentik im Werk zeitgenössischer Architekten wie Herzog & De Meuron oder Farshid Moussavi zuwenden. Diese drei BĂŒcher zeichnen sich dadurch aus, dass sie die vorgefasste Meinung ĂŒber das Ornament als bloĂe schmĂŒckende ErgĂ€nzung eines Gegenstands und damit als ĂŒberflĂŒssige Erscheinung grundlegend hinterfragen. Sie zeigen auf unterschiedliche Weise, dass die Frage des Ornaments vielmehr im Zentrum der menschlichen Kunst und materiellen Kultur steht.I tre libri qui studiati mettono sotto una luce nuova la complessa storia dellâornamento in Occidente. Lo studio di Clare Guest sulla comprensione dellâornamento nel Rinascimento Ăš un tentativo ambizioso ed erudito di rintracciare la preistoria dei concetti prima dellâemergere dellâestetica kantiana. Guest risale alle origini del pensiero occidentale sullâornamento, allâAntico Testamento, al pensiero Greco platonico, aristotelico e sofista, e alla scolastica, per ritrovare una concezione dellâornamento e della bellezza che non sia relativa e che sia comunque in armonia con lâidea greca secondo la quale lâornamento rappresenta il bagliore della veritĂ e della bellezza. Il libro di RĂ©mi Labrusse si concentra sulla storia dellâornamento dopo il momento kantiano. Si tratta di uno studio denso e molto sofisticato dei tentativi del xix secolo di ripensare lâornamento, la sua concezione e la sua storia, davanti alle sfide poste dallâemergere di una presa di coscienza della natura globale dellâarte e dellâornamento umano e dei cambiamenti radicali che la rivoluzione industriale ha impresso sulla produzione artistica. Ă un nuovo inizio fondamentale. Dedicato invece al xx secolo, il volume Histories of Ornament. From Global to Local, diretto da GĂŒlru Necipoglu e Alina Payne, rimette in questione il paradigma modernista, o piuttosto il suo rifiuto dellâornamento, a partire dal ritorno dellâornamentazione di superfice nellâopera di architetti contemporanei come Herzog & De Meuron o Farshid Moussavi. Questi tre libri si distinguono per una fondamentale messa in causa dei luoghi comuni sullâornamento concepito come complemento dellâoggetto che adorna, e dunque superfluo, e mostrano in modi differenti che la questione dellâornamento Ăš al centro dellâarte e della cultura materiale umana.Los tres libros estudiados aquĂ dan nueva luz sobre la compleja historia del ornamento en Occidente. El estudio de Clare Guest sobre la comprensiĂłn del ornamento durante el Renacimiento es una tentativa ambiciosa y bastante erudita de trazar la historia de conceptos antes de la emergencia de la estĂ©tica kantiana. Guest se remonta a los inicios del pensamiento occidental sobre el ornamento, al Antiguo Testamento, el pensamiento griego platĂłnico, aristotĂ©lico y sofĂstico, y a la escolĂĄstica, para encontrar una concepciĂłn del ornamento y de la belleza que no sea determinada a partir de un concepto relativo a la belleza, y que resuene al mismo tiempo con la idea griega segĂșn la cual el ornamento serĂa el brillo de la verdad y de la belleza. El libro de RĂ©mi Labrusse se centra por su parte en la historia del ornamento despuĂ©s del momento kantiano. Se trata de un estudio igual de denso y de sofisticado sobre las tentativas del siglo xix por pensar el ornamento, su concepciĂłn y su historia, frente a los desafĂos planteados por la emergencia de una toma de consciencia sobre la naturaleza global del arte y de la ornamentaciĂłn humana y de los cambios radicales que la revoluciĂłn industrial imprime a la producciĂłn artĂstica. Es un nuevo inicio fundamental. Inclinado hacia el siglo xx, el volumen Histories of Ornament. From Global to Local, dirigido por GĂŒlru Necipoglu y Alina Payne, cuestiona el paradigma modernista, o mĂĄs bien su rechazo al ornamento, a partir del resurgimiento de la ornamentaciĂłn de superficies en la obra de arquitectos contemporĂĄneos como Herzog & De Meuron o Farshid Moussavi. Estos tres libros se distinguen por una crĂtica fundamental a lugares comunes sobre el ornamento concebido como complemento del objeto que este adorna, y por lo tanto como superfluo, y muestran diferentes maneras en las que las problemĂĄticas del ornamento se encuentran en el corazĂłn del arte y de la cultura material humana
Situations "médusantes", figuration, pétrification et peur des images
International audienceDans ses notes des annĂ©es 1800, le poĂšte allemand Novalis nota, Ă propos du laocoon : « Ne peut-on pas concevoir, dans ce drame de Laocoon, un moment supĂ©rieur, un bref instant de culmination qui embrasserait tout Ă un plus haut degrĂ© comme, peut-ĂȘtre, celui oĂč la suprĂȘme douleur se transforme en ivresse, la rĂ©sistance en abandon, et la suprĂȘme vie en pierre ?
1990-2010 : vingt ans dâhistoriographie nĂ©erlandaise
Caroline van Eck | Enjeux disciplinaires et politiques de la recherche Depuis la Seconde Guerre mondiale, deux Ă©vĂ©nements intellectuels majeurs ont marquĂ© lâĂ©volution de lâhistoire de lâart en tant que discipline acadĂ©mique dans le monde occidental : dâune part, lâĂ©migration vers la Grande-Bretagne et les Ătats-Unis dâhistoriens de lâart allemands et autrichiens tels que Edward Wind, Nikolaus Pevsner, Ernst Gombrich, Rudolf Wittkower et Erwin Panofsky et, dâautre part, lâĂ©mergence dans les a..
Health-related quality of life and symptom burden in patients on haemodialysis
BACKGROUND: Patients on haemodialysis generally experience poor health-related quality of life (HRQoL) and a broad range of physical and mental symptoms, but it is unknown whether this differs between younger and older patients. We aimed to describe the trajectories of HRQoL and symptom burden of patients < 70 and â„ 70 years old, and to assess the impact of symptom burden on HRQoL.METHODS: In incident Dutch haemodialysis patients, HRQoL and symptoms were measured with the 12-item Short Form Health Survey and Dialysis Symptom Index. We used linear mixed models for examining the trajectories of HRQoL and symptom burden during the first year of dialysis, and linear regression for the impact of symptom burden on HRQoL.RESULTS: In 774 patients, the trajectories of physical HRQoL, mental HRQoL, and symptom burden were stable during the first year of dialysis. Compared with patients aged < 70 years, patients â„ 70 years reported similar physical HRQoL (mean difference -0.61, 95% CI -1.86; 0.63), better mental HRQoL (1.77, 95% CI 0.54; 3.01), and lower symptom burden (-2.38, 95% CI -5.08; 0.32). With increasing symptom burden, physical HRQoL declined more in older than in younger patients (ÎČ -0.287 versus -0.189, respectively, p-value for interaction = 0.007). For mental HRQoL, this decrease was similar in both age groups (ÎČ -0.295 versus -0.288, P = 0.847).CONCLUSIONS: Older haemodialysis patients generally experience a better mental HRQoL and a (non-statistically significant) lower symptom burden, compared to younger patients. Their physical HRQoL declines more rapidly with increasing symptom burden.</p
The Science Performance of JWST as Characterized in Commissioning
This paper characterizes the actual science performance of the James Webb
Space Telescope (JWST), as determined from the six month commissioning period.
We summarize the performance of the spacecraft, telescope, science instruments,
and ground system, with an emphasis on differences from pre-launch
expectations. Commissioning has made clear that JWST is fully capable of
achieving the discoveries for which it was built. Moreover, almost across the
board, the science performance of JWST is better than expected; in most cases,
JWST will go deeper faster than expected. The telescope and instrument suite
have demonstrated the sensitivity, stability, image quality, and spectral range
that are necessary to transform our understanding of the cosmos through
observations spanning from near-earth asteroids to the most distant galaxies.Comment: 5th version as accepted to PASP; 31 pages, 18 figures;
https://iopscience.iop.org/article/10.1088/1538-3873/acb29
Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK.
BACKGROUND: A safe and efficacious vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), if deployed with high coverage, could contribute to the control of the COVID-19 pandemic. We evaluated the safety and efficacy of the ChAdOx1 nCoV-19 vaccine in a pooled interim analysis of four trials. METHODS: This analysis includes data from four ongoing blinded, randomised, controlled trials done across the UK, Brazil, and South Africa. Participants aged 18 years and older were randomly assigned (1:1) to ChAdOx1 nCoV-19 vaccine or control (meningococcal group A, C, W, and Y conjugate vaccine or saline). Participants in the ChAdOx1 nCoV-19 group received two doses containing 5âĂâ1010 viral particles (standard dose; SD/SD cohort); a subset in the UK trial received a half dose as their first dose (low dose) and a standard dose as their second dose (LD/SD cohort). The primary efficacy analysis included symptomatic COVID-19 in seronegative participants with a nucleic acid amplification test-positive swab more than 14 days after a second dose of vaccine. Participants were analysed according to treatment received, with data cutoff on Nov 4, 2020. Vaccine efficacy was calculated as 1â-ârelative risk derived from a robust Poisson regression model adjusted for age. Studies are registered at ISRCTN89951424 and ClinicalTrials.gov, NCT04324606, NCT04400838, and NCT04444674. FINDINGS: Between April 23 and Nov 4, 2020, 23â848 participants were enrolled and 11â636 participants (7548 in the UK, 4088 in Brazil) were included in the interim primary efficacy analysis. In participants who received two standard doses, vaccine efficacy was 62·1% (95% CI 41·0-75·7; 27 [0·6%] of 4440 in the ChAdOx1 nCoV-19 group vs71 [1·6%] of 4455 in the control group) and in participants who received a low dose followed by a standard dose, efficacy was 90·0% (67·4-97·0; three [0·2%] of 1367 vs 30 [2·2%] of 1374; pinteraction=0·010). Overall vaccine efficacy across both groups was 70·4% (95·8% CI 54·8-80·6; 30 [0·5%] of 5807 vs 101 [1·7%] of 5829). From 21 days after the first dose, there were ten cases hospitalised for COVID-19, all in the control arm; two were classified as severe COVID-19, including one death. There were 74â341 person-months of safety follow-up (median 3·4 months, IQR 1·3-4·8): 175 severe adverse events occurred in 168 participants, 84 events in the ChAdOx1 nCoV-19 group and 91 in the control group. Three events were classified as possibly related to a vaccine: one in the ChAdOx1 nCoV-19 group, one in the control group, and one in a participant who remains masked to group allocation. INTERPRETATION: ChAdOx1 nCoV-19 has an acceptable safety profile and has been found to be efficacious against symptomatic COVID-19 in this interim analysis of ongoing clinical trials. FUNDING: UK Research and Innovation, National Institutes for Health Research (NIHR), Coalition for Epidemic Preparedness Innovations, Bill & Melinda Gates Foundation, Lemann Foundation, Rede D'Or, Brava and Telles Foundation, NIHR Oxford Biomedical Research Centre, Thames Valley and South Midland's NIHR Clinical Research Network, and AstraZeneca
Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK
Background
A safe and efficacious vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), if deployed with high coverage, could contribute to the control of the COVID-19 pandemic. We evaluated the safety and efficacy of the ChAdOx1 nCoV-19 vaccine in a pooled interim analysis of four trials.
Methods
This analysis includes data from four ongoing blinded, randomised, controlled trials done across the UK, Brazil, and South Africa. Participants aged 18 years and older were randomly assigned (1:1) to ChAdOx1 nCoV-19 vaccine or control (meningococcal group A, C, W, and Y conjugate vaccine or saline). Participants in the ChAdOx1 nCoV-19 group received two doses containing 5âĂâ1010 viral particles (standard dose; SD/SD cohort); a subset in the UK trial received a half dose as their first dose (low dose) and a standard dose as their second dose (LD/SD cohort). The primary efficacy analysis included symptomatic COVID-19 in seronegative participants with a nucleic acid amplification test-positive swab more than 14 days after a second dose of vaccine. Participants were analysed according to treatment received, with data cutoff on Nov 4, 2020. Vaccine efficacy was calculated as 1â-ârelative risk derived from a robust Poisson regression model adjusted for age. Studies are registered at ISRCTN89951424 and ClinicalTrials.gov, NCT04324606, NCT04400838, and NCT04444674.
Findings
Between April 23 and Nov 4, 2020, 23â848 participants were enrolled and 11â636 participants (7548 in the UK, 4088 in Brazil) were included in the interim primary efficacy analysis. In participants who received two standard doses, vaccine efficacy was 62·1% (95% CI 41·0â75·7; 27 [0·6%] of 4440 in the ChAdOx1 nCoV-19 group vs71 [1·6%] of 4455 in the control group) and in participants who received a low dose followed by a standard dose, efficacy was 90·0% (67·4â97·0; three [0·2%] of 1367 vs 30 [2·2%] of 1374; pinteraction=0·010). Overall vaccine efficacy across both groups was 70·4% (95·8% CI 54·8â80·6; 30 [0·5%] of 5807 vs 101 [1·7%] of 5829). From 21 days after the first dose, there were ten cases hospitalised for COVID-19, all in the control arm; two were classified as severe COVID-19, including one death. There were 74â341 person-months of safety follow-up (median 3·4 months, IQR 1·3â4·8): 175 severe adverse events occurred in 168 participants, 84 events in the ChAdOx1 nCoV-19 group and 91 in the control group. Three events were classified as possibly related to a vaccine: one in the ChAdOx1 nCoV-19 group, one in the control group, and one in a participant who remains masked to group allocation.
Interpretation
ChAdOx1 nCoV-19 has an acceptable safety profile and has been found to be efficacious against symptomatic COVID-19 in this interim analysis of ongoing clinical trials
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