Baseline characteristics of recruited individuals stratified by diagnosis at baseline.

<p>Baseline characteristics of recruited individuals stratified by diagnosis at baseline.</p

Number of RRMS patients who initiated a DMD since 2 years before baseline, treatment exposure time, number of relapses, number of patients experiencing a relapse and annualized relapse rate (ARR).

<p>Only DMDs used in at least 10 SMSC patients and with at least 1 year of mean follow-up are shown.</p

Distribution of age at baseline of all SMSC patients coloured by gender.

<p>Distribution of age at baseline of all SMSC patients coloured by gender.</p

Boxplots of age at first symptom in CIS, RRMS-SPMS (combined) and PPMS patients, together with age at onset of progression in SPMS patients.

<p>Boxplots of age at first symptom in CIS, RRMS-SPMS (combined) and PPMS patients, together with age at onset of progression in SPMS patients.</p

Number and percentage of patients under MS specific DMDs at baseline.

<p>Number and percentage of patients under MS specific DMDs at baseline.</p

Boxplots of change in EDSS between baseline and most recent visit stratified by disease course at most recent visit and presence of relapses between baseline and most recent visit.

<p>Only patients with at least two study visits are included.</p

Number of recruited SMSC patients between June 2012 and July 2015.

<p>Number of recruited SMSC patients between June 2012 and July 2015.</p

Distribution of EDSS at baseline of all SMSC patients coloured by disease course.

<p>Distribution of EDSS at baseline of all SMSC patients coloured by disease course.</p