Prevalence of COPD adjusted for age and stratified by smoking status.

<p>Prevalence of COPD adjusted for age and stratified by smoking status.</p

Information on genotyped and imputed SNPs.

*<p>The WHII study was typed at two centres with different array readers, which were compared and shown to be concordant.</p

Disease event definitions, incident and prevalent events by disease and medication use in the UCLEB consortium.

<p>Total incident CHD =  incident non-fatal MI or revascularization plus fatal CHD (ICD codes I20–I25, I516).</p><p>Total prevalent CHD  =  prevalent non-fatal MI or revascularization.</p><p>Total incident stroke  =  incident non-fatal stroke (ischaemic & haemorrhagic combined, but excluding TIA) plus fatal stroke (ICD codes I60×, I61×, I62, I629 I63×, I64× I65× I66×, I67, I672, I678, I679, I69×, G46×, G450, G451, G452, G453).</p><p>Total diabetes defined by a combination of self-report, medical history review, use of glucose lowering medication, or fasting glucose >7 mmol/L.</p>*<p>1958BC are currently undertaking case ascertainment.</p

Additional file 1: Table S1. of Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals

Discovery results for all models that passed replication thresholds for MEF analysis. Column header definitions provided at the end. Table S2. Discovery results for all models that passed replication thresholds for Biofilter analysis. Column header definitions provided at the end. (PDF 1649 kb

Association of rs16969968-rs1051730 with body mass index, weight and height, stratified by smoking status.

<p>All analyses were adjusted for age. Effect estimate represents per minor allele percentage change for BMI and weight (log transformed for analysis), and per minor allele change in cm for height.</p><p>Association of rs16969968-rs1051730 with body mass index, weight and height, stratified by smoking status.</p