Clinical, anthropometric, metabolic variables and nocturnal respiratory registration data in PM and M obese women according to the presence of OSA.

<p>FH: family history; BMI: body mass index; BP: blood pressure; IFG: impaired fasting glucose; IGT: impaired glucose tolerance; ISI: insulin sensitivity index; ΔI₃₀/ΔG_30: insulinogenic index; CRP: C- reactive protein; ESS: Epworth Sleepiness Scale; AHI: Apnea-Hypopnea Index; ODI: Oxygen Desaturation Index; SaO₂: nocturnal oxygen saturation. Data are expressed as mean ± SD except for CRP which is expressed as median (interquartile range).</p>a<p>p<0.05,</p>b<p>p<0.01,</p>c<p>p<0.0001 OSA vs no OSA women;</p>§<p>p<0.05,</p>§§<p>p<0.001 no OSA premenopausal vs no OSA menopausal women;</p>#<p>p<0.01 premenopausal OSA vs menopausal OSA women.</p

Correlation coefficients of nocturnal respiratory registration data with obesity indexes, insulin sensitivity and fasting glucose in 98 obese women.

<p>BMI: body mass index; WHR: waist/height ratio; NHR: neck/height ratio; FM/FFM: fat mass/fat free mass ratio; FPG: fasting glucose; 2 h PG: 2 h glucose; ISI: insulin sensitivity index; AHI: Apnea-Hypopnea Index; ODI: Oxygen Desaturation Index; mean SaO₂: mean nocturnal oxygen saturation; min SaO₂: minimal nocturnal oxygen saturation.</p

Study variables assessed at high altitude in baseline condition, after 15 minutes of slow breathing exercise and after 5 and 30 minutes of recovery.

<p>Data are separately shown for Study A and B.</p>*<p>-p<0.05, **-p<0.01, ***, p<0.001 vs. baseline; † - p<0.05, †† - p<0.01, †††, p<0.001 vs. slow breathing.</p><p>Sp_O2, blood oxygen saturation; p_tO2– transcutaneous oxygen partial pressure; pt_CO2– transcutaneous CO₂ partial pressure; Et_CO2– end tidal CO₂ pressure in the exhaled air; SBP – systolic blood pressure; DBP – diastolic blood pressure; PP – pulse pressure; HR – heart rate; sPAP – systolic pulmonary artery pressure; RF – respiratory frequency; Vt – tidal volume; VE – minute ventilation; VA – alveolar volume; Dl_CO - pulmonary CO diffusion; TFC – thoracic fluid content.</p

Schematic representation of the sequence of data collection in studies A and B.

<p>Sp_O2, blood oxygen saturation; Pt_O2, transcutaneous oxygen partial pressure; Pt_CO2, transcutaneous CO₂ partial pressure; HR, heart rate; BP, blood pressure; RF, respiratory frequency; PAP, pulmonary artery pressure; Vt, tidal volume; VE, minute ventilation; Dl_CO, pulmonary CO diffusion; VA = alveolar volume; TFC, thoracic fluid content; Pet_CO2, end tidal CO₂ pressure in the exhaled air.</p